STRINGSTRING
PPP4R3B PPP4R3B PLCB2 PLCB2 ATF2 ATF2 PDHA1 PDHA1 PCK1 PCK1 AKT2 AKT2 PPP3CB PPP3CB CAMK2D CAMK2D GYS1 GYS1 PYGL PYGL PRKAB1 PRKAB1 PYGB PYGB SIK1 SIK1 PPP3CA PPP3CA PGAM2 PGAM2 SLC2A1 SLC2A1 CALM3 CALM3 GYS2 GYS2 LDHB LDHB EP300 EP300 PHKA1 PHKA1 PDE3B PDE3B ITPR2 ITPR2 PRKAA2 PRKAA2 PPARA PPARA ADCY2 ADCY2 PFKFB1 PFKFB1 PRKAG1 PRKAG1 CREB3L2 CREB3L2 PHKA2 PHKA2 TNIK TNIK PPARGC1A PPARGC1A PPP4C PPP4C PRMT1 PRMT1 CPT1C CPT1C GCK GCK PGAM1 PGAM1 PRKAG3 PRKAG3 ATF4 ATF4 PFKL PFKL CAMK2A CAMK2A ARSI ARSI PRKACA PRKACA PFKP PFKP PHKG1 PHKG1 CREB5 CREB5 PDHB PDHB PFKM PFKM CREB1 CREB1 GNAS GNAS CALML4 CALML4 SIRT1 SIRT1 CREB3L1 CREB3L1 CPT1A CPT1A CREBBP CREBBP PRKAG2 PRKAG2 ENSTTRP00000016529 ENSTTRP00000016529 NOSTRIN NOSTRIN G6PC2 G6PC2 FBP2 FBP2 FBP1 FBP1 ACACB ACACB ITPR3 ITPR3 SLC2A2 SLC2A2 CAMK2B CAMK2B PCK2 PCK2 GNAQ GNAQ PYGM PYGM ACACA ACACA PKM PKM PARP6 PARP6 PLCB1 PLCB1 CREB3L3 CREB3L3 PLCB3 PLCB3 PRKAB2 PRKAB2 PHKB PHKB G6PC3 G6PC3 SIK2 SIK2 PRKAA1 PRKAA1 CRTC2 CRTC2 CREB3L4 CREB3L4 CALML6 CALML6 PRKACB PRKACB AKT3 AKT3 G6PC G6PC CREB3 CREB3 CALM2 CALM2 CAMK2G CAMK2G FOXO1 FOXO1 PPP3CC PPP3CC PARP8 PARP8 PHKG2 PHKG2 ENSTTRP00000012598 ENSTTRP00000012598 CALM1 CALM1 PPP4R3A PPP4R3A LDHA LDHA LDHAL6A LDHAL6A GCG GCG FAP FAP PLCB4 PLCB4 CPT1B CPT1B AKT1 AKT1 ITPR1 ITPR1 ENSTTRP00000013721 ENSTTRP00000013721
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP4R3BSerine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1. (839 aa)
PLCB2Phosphoinositide phospholipase C. (1184 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1. (390 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily. (498 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (721 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (768 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1 isoform X2. (270 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
SIK1Serine/threonine-protein kinase SIK1 isoform X1. (718 aa)
PPP3CASerine/threonine-protein phosphatase. (560 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (249 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (486 aa)
CALM3Calmodulin 3. (148 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (702 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (327 aa)
EP300Histone acetyltransferase p300. (2422 aa)
PHKA1Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1240 aa)
PDE3BPhosphodiesterase. (1045 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (469 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1. (471 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X2. (356 aa)
CREB3L2LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
PHKA2Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1233 aa)
TNIKTRAF2 and NCK-interacting protein kinase. (1365 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (796 aa)
PPP4CProtein phosphatase 4 catalytic subunit. (307 aa)
PRMT1Protein arginine methyltransferase 1. (360 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform. (672 aa)
GCKPhosphotransferase. (496 aa)
PGAM1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (204 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (486 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
PFKLATP-dependent 6-phosphofructokinase, liver type. (743 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (539 aa)
ARSIArylsulfatase I. (571 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (778 aa)
PHKG1Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform X2; Belongs to the protein kinase superfamily. (390 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (358 aa)
PFKMATP-dependent 6-phosphofructokinase, muscle type isoform X1. (851 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
CALML4Calmodulin-like protein 4 isoform X2. (195 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (616 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
CPT1ALOW QUALITY PROTEIN: carnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family. (726 aa)
CREBBPCREB-binding protein isoform X6. (2402 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (568 aa)
ENSTTRP00000016529annotation not available (169 aa)
NOSTRINNostrin isoform X1. (506 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
FBP2Fructose-bisphosphatase 2. (339 aa)
FBP1Fructose-1,6-bisphosphatase 1; Belongs to the FBPase class 1 family. (276 aa)
ACACBacetyl-CoA carboxylase 2. (2474 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (489 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (560 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
ACACAacetyl-CoA carboxylase 1 isoform X1. (2414 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PARP6Poly [ADP-ribose] polymerase. (551 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (455 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (247 aa)
PHKBPhosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1090 aa)
G6PC3LOW QUALITY PROTEIN: glucose-6-phosphatase 3-like. (346 aa)
SIK2Serine/threonine-protein kinase SIK2 isoform X2. (898 aa)
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)
CRTC2CREB-regulated transcription coactivator 2 isoform X1. (672 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X3. (395 aa)
CALML6Calmodulin-like protein 6. (179 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (365 aa)
CALM2Calmodulin 2. (148 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5. (535 aa)
FOXO1Forkhead box protein O1. (538 aa)
PPP3CCSerine/threonine-protein phosphatase. (535 aa)
PARP8Poly [ADP-ribose] polymerase. (822 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform isoform X2; Belongs to the protein kinase superfamily. (405 aa)
ENSTTRP00000012598annotation not available (238 aa)
CALM1Calmodulin; Belongs to the calmodulin family. (149 aa)
PPP4R3ASerine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X3. (820 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (331 aa)
LDHAL6ALactate dehydrogenase A like 6A. (304 aa)
GCGGlucagon isoform X2. (183 aa)
FAPProlyl endopeptidase FAP isoform X2; Belongs to the peptidase S9B family. (759 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X2; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
AKT1AKT serine/threonine kinase 1. (480 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
ENSTTRP00000013721annotation not available (118 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (22%) [HD]