STRINGSTRING
PTGS2 PTGS2 NPPA NPPA AKT3 AKT3 PRKACB PRKACB ADCY6 ADCY6 ENSTTRP00000010030 ENSTTRP00000010030 TSHB TSHB SYCP1 SYCP1 ADORA1 ADORA1 LOC101315796 LOC101315796 INSR INSR ENSTTRP00000008430 ENSTTRP00000008430 ADCY4 ADCY4 ADRB2 ADRB2 GNAI2 GNAI2 NPY NPY PTGS1 PTGS1 FABP4 FABP4 ENSTTRP00000006580 ENSTTRP00000006580 PMP2 PMP2 PIK3CB PIK3CB GNAI1 GNAI1 ENSTTRP00000005523 ENSTTRP00000005523 ADRB1 ADRB1 ADCY2 ADCY2 PRKG2 PRKG2 PDE3B PDE3B PRKG1 PRKG1 PIK3CD PIK3CD NPY1R NPY1R ADCY9 ADCY9 GNAI3 GNAI3 AKT2 AKT2 TSHR TSHR ADCY5 ADCY5 ABHD5 ABHD5 MGLL MGLL PIK3R1 PIK3R1 GNAS GNAS PLIN1 PLIN1 ENSTTRP00000014640 ENSTTRP00000014640 ADCY3 ADCY3 PTRHD1 PTRHD1 NPR1 NPR1 PRKACA PRKACA PTGER3 PTGER3 AKT1 AKT1 PIK3CA PIK3CA LIPE LIPE ADCY8 ADCY8 ADCY7 ADCY7 PLAAT3 PLAAT3 ADCY1 ADCY1 PIK3R3 PIK3R3 PNPLA2 PNPLA2 CGA CGA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTGS2Prostaglandin G/H synthase 2. (603 aa)
NPPAAtrial natriuretic peptide. (177 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
ADCY6Adenylate cyclase 6. (1167 aa)
ENSTTRP00000010030annotation not available (338 aa)
TSHBThyroid stimulating hormone beta subunit. (140 aa)
SYCP1Synaptonemal complex protein 1. (945 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (212 aa)
LOC101315796LOW QUALITY PROTEIN: fatty acid-binding protein 12. (89 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
ENSTTRP00000008430annotation not available (252 aa)
ADCY4Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
GNAI2G protein subunit alpha i2. (351 aa)
NPYPro-neuropeptide Y isoform X2. (97 aa)
PTGS1Prostaglandin G/H synthase 1. (600 aa)
FABP4Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
ENSTTRP00000006580annotation not available (132 aa)
PMP2Myelin P2 protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
ENSTTRP00000005523annotation not available (722 aa)
ADRB1Beta-1 adrenergic receptor. (467 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PDE3BPhosphodiesterase. (1045 aa)
PRKG1cGMP-dependent protein kinase 1; Belongs to the protein kinase superfamily. (686 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1049 aa)
NPY1RNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
GNAI3G protein subunit alpha i3. (354 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
ABHD51-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X1. (349 aa)
MGLLMonoglyceride lipase isoform X1. (308 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (732 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
PLIN1Perilipin 1. (517 aa)
ENSTTRP00000014640annotation not available (143 aa)
ADCY3Adenylate cyclase type 3. (1141 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
NPR1Natriuretic peptide receptor 1. (1055 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype isoform X2. (448 aa)
AKT1AKT serine/threonine kinase 1. (480 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa)
LIPELipase E, hormone sensitive type. (1042 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
ADCY7Adenylate cyclase type 7-like. (1080 aa)
PLAAT3HRAS-like suppressor 3 isoform X2. (162 aa)
ADCY1Adenylate cyclase 1. (1088 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2. (501 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (118 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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