STRINGSTRING
PLCB2 PLCB2 CACNA1G CACNA1G CACNA1H CACNA1H ATF2 ATF2 ADCY5 ADCY5 CACNA1I CACNA1I CAMK2D CAMK2D SCARB1 SCARB1 ATP1A2 ATP1A2 ATP1A4 ATP1A4 PRKCB PRKCB ADCY9 ADCY9 NR4A1 NR4A1 KCNK9 KCNK9 ATP1B4 ATP1B4 PDE2A PDE2A CACNA1C CACNA1C CALM3 CALM3 ITPR2 ITPR2 ATF1 ATF1 AGT AGT ADCY2 ADCY2 ATP2B2 ATP2B2 STAR STAR CREB3L2 CREB3L2 DAGLB DAGLB ATP1B1 ATP1B1 NR4A2 NR4A2 CYP21A2 CYP21A2 ATF6B ATF6B POMC POMC ATP2B1 ATP2B1 PRKD3 PRKD3 ITPR3 ITPR3 CAMK4 CAMK4 CAMK2B CAMK2B CYP11A1 CYP11A1 PRKCA PRKCA ENSTTRP00000007871 ENSTTRP00000007871 ADCY4 ADCY4 GNAQ GNAQ CAMK1D CAMK1D AGTR1 AGTR1 LDLR LDLR KCNJ5 KCNJ5 PLCB1 PLCB1 CAMK1 CAMK1 CREB3L3 CREB3L3 ATP1B2 ATP1B2 KCNK3 KCNK3 PLCB3 PLCB3 PRKCG PRKCG CREB3L4 CREB3L4 DAGLA DAGLA CALML6 CALML6 ADCY6 ADCY6 PRKACB PRKACB NPPA NPPA ATP1A1 ATP1A1 ATP2B3 ATP2B3 PRKCE PRKCE CREB3 CREB3 CALM2 CALM2 ATP1B3 ATP1B3 CAMK2G CAMK2G CACNA1D CACNA1D GNA11 GNA11 PRKD2 PRKD2 ADCY1 ADCY1 ADCY7 ADCY7 ADCY8 ADCY8 CALM1 CALM1 CACNA1S CACNA1S LIPE LIPE PLCB4 PLCB4 ORAI1 ORAI1 PRKD1 PRKD1 ITPR1 ITPR1 ENSTTRP00000013721 ENSTTRP00000013721 ATF4 ATF4 CAMK2A CAMK2A ARSI ARSI PRKACA PRKACA NPR1 NPR1 PTRHD1 PTRHD1 ADCY3 ADCY3 CREB5 CREB5 CREB1 CREB1 GNAS GNAS CALML4 CALML4 LOC101319007 LOC101319007 MC2R MC2R ATP2B4 ATP2B4 CREB3L1 CREB3L1 CACNA1F CACNA1F CAMK1G CAMK1G
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB2Phosphoinositide phospholipase C. (1184 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha-1G. (2374 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2337 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2228 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily. (498 aa)
SCARB1Scavenger receptor class B member 1. (465 aa)
ATP1A2ATPase Na+/K+ transporting subunit alpha 2. (1020 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1009 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (632 aa)
KCNK9Potassium channel subfamily K member 9. (373 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
PDE2APhosphodiesterase. (936 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha-1C-like. (2195 aa)
CALM3Calmodulin 3. (148 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X5. (191 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ATP2B2ATPase plasma membrane Ca2+ transporting 2. (1243 aa)
STARSteroidogenic acute regulatory protein, mitochondrial. (285 aa)
CREB3L2LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
DAGLBSn1-specific diacylglycerol lipase beta. (669 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (284 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2 isoform X4. (598 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2. (496 aa)
ATF6BActivating transcription factor 6 beta. (671 aa)
POMCPro-opiomelanocortin. (259 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1217 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (891 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (473 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (489 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (518 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
ENSTTRP00000007871annotation not available (1012 aa)
ADCY4Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase type 1D; Belongs to the protein kinase superfamily. (385 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LDLRLow-density lipoprotein receptor. (842 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4 isoform X1. (419 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
CAMK1Calcium/calmodulin-dependent protein kinase type 1. (370 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (455 aa)
ATP1B2ATPase Na+/K+ transporting subunit beta 2. (290 aa)
KCNK3Potassium channel subfamily K member 3. (396 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
PRKCGProtein kinase C gamma type. (697 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X3. (395 aa)
DAGLASn1-specific diacylglycerol lipase alpha. (1039 aa)
CALML6Calmodulin-like protein 6. (179 aa)
ADCY6Adenylate cyclase 6. (1167 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
NPPAAtrial natriuretic peptide. (177 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
ATP2B3ATPase plasma membrane Ca2+ transporting 3. (1218 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (365 aa)
CALM2Calmodulin 2. (148 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (277 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5. (535 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
GNA11G protein subunit alpha 11. (359 aa)
PRKD2Serine/threonine-protein kinase D2. (837 aa)
ADCY1Adenylate cyclase 1. (1088 aa)
ADCY7Adenylate cyclase type 7-like. (1080 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
CALM1Calmodulin; Belongs to the calmodulin family. (149 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha-1S-like. (1856 aa)
LIPELipase E, hormone sensitive type. (1042 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
ORAI1Calcium release-activated calcium channel protein 1. (238 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (876 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
ENSTTRP00000013721annotation not available (118 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (539 aa)
ARSIArylsulfatase I. (571 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
NPR1Natriuretic peptide receptor 1. (1055 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
ADCY3Adenylate cyclase type 3. (1141 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
CALML4Calmodulin-like protein 4 isoform X2. (195 aa)
LOC1013190073 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (369 aa)
MC2RAdrenocorticotropic hormone receptor. (297 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1208 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha-1F isoform X1. (1973 aa)
CAMK1GCalcium/calmodulin-dependent protein kinase type 1G; Belongs to the protein kinase superfamily. (474 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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