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KCNA1 KCNA1 CREB3L4 CREB3L4 ADCY6 ADCY6 PRKACB PRKACB CREB3 CREB3 MC2R MC2R LOC101319007 LOC101319007 NR5A1 NR5A1 CACNA1F CACNA1F CACNA1D CACNA1D GNA11 GNA11 CYP17A1 CYP17A1 NR0B1 NR0B1 ADCY1 ADCY1 ADCY7 ADCY7 ADCY8 ADCY8 PLCB2 PLCB2 CACNA1G CACNA1G LOC101316201 LOC101316201 CACNA1H CACNA1H ATF2 ATF2 ADCY5 ADCY5 CACNA1I CACNA1I ORAI1 ORAI1 ITPR1 ITPR1 ATF4 ATF4 KCNA2 KCNA2 PRKACA PRKACA NCEH1 NCEH1 PTRHD1 PTRHD1 ADCY3 ADCY3 CREB5 CREB5 CREB1 CREB1 GNAS GNAS CREB3L1 CREB3L1 SCARB1 SCARB1 ADCY9 ADCY9 NR4A1 NR4A1 CACNA1C CACNA1C ITPR2 ITPR2 AGT AGT PDE8A PDE8A ADCY2 ADCY2 STAR STAR CREB3L2 CREB3L2 CYP21A2 CYP21A2 ATF6B ATF6B PBX1 PBX1 POMC POMC ITPR3 ITPR3 PLCB4 PLCB4 KCNA4 KCNA4 MRAP MRAP CYP11A1 CYP11A1 ADCY4 ADCY4 GNAQ GNAQ KCNK2 KCNK2 PDE8B PDE8B CACNA1S CACNA1S AGTR1 AGTR1 LDLR LDLR SP1 SP1 PLCB1 PLCB1 KCNA10 KCNA10 CREB3L3 CREB3L3 KCNK3 KCNK3 PLCB3 PLCB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X3. (395 aa)
ADCY6Adenylate cyclase 6. (1167 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (365 aa)
MC2RAdrenocorticotropic hormone receptor. (297 aa)
LOC1013190073 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (369 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha-1F isoform X1. (1973 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
GNA11G protein subunit alpha 11. (359 aa)
CYP17A1Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (508 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
ADCY1Adenylate cyclase 1. (1088 aa)
ADCY7Adenylate cyclase type 7-like. (1080 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
PLCB2Phosphoinositide phospholipase C. (1184 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha-1G. (2374 aa)
LOC101316201Cytochrome P450 11B1, mitochondrial; Belongs to the cytochrome P450 family. (371 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2337 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
CACNA1ICalcium voltage-gated channel subunit alpha1 I. (2228 aa)
ORAI1Calcium release-activated calcium channel protein 1. (238 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (278 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
ADCY3Adenylate cyclase type 3. (1141 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
SCARB1Scavenger receptor class B member 1. (465 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (632 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha-1C-like. (2195 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
PDE8APhosphodiesterase. (830 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
STARSteroidogenic acute regulatory protein, mitochondrial. (285 aa)
CREB3L2LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2. (496 aa)
ATF6BActivating transcription factor 6 beta. (671 aa)
PBX1pre-B-cell leukemia transcription factor 1 isoform X2. (430 aa)
POMCPro-opiomelanocortin. (259 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
KCNA4Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (656 aa)
MRAPMelanocortin-2 receptor accessory protein. (174 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (518 aa)
ADCY4Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
KCNK2Potassium channel subfamily K member 2 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
PDE8BPhosphodiesterase. (885 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha-1S-like. (1856 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LDLRLow-density lipoprotein receptor. (842 aa)
SP1Transcription factor Sp1. (784 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (508 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (455 aa)
KCNK3Potassium channel subfamily K member 3. (396 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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