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ATP1B3 ATP1B3 CFTR CFTR CALML4 CALML4 GNAS GNAS KCNJ15 KCNJ15 ADCY3 ADCY3 PTRHD1 PTRHD1 ATP4A ATP4A PRKACA PRKACA ARSI ARSI CAMK2A CAMK2A ACTL8 ACTL8 ENSTTRP00000013721 ENSTTRP00000013721 ITPR1 ITPR1 PLCB4 PLCB4 CALM1 CALM1 ADCY8 ADCY8 ADCY7 ADCY7 ADCY1 ADCY1 MYLK3 MYLK3 KCNQ1 KCNQ1 SST SST KCNK10 KCNK10 CAMK2G CAMK2G CALM2 CALM2 ATP1A1 ATP1A1 EZR EZR PRKACB PRKACB ADCY6 ADCY6 CALML6 CALML6 SLC9A4 SLC9A4 PRKCG PRKCG PLCB3 PLCB3 ATP1B2 ATP1B2 PLCB1 PLCB1 KCNK2 KCNK2 GNAQ GNAQ ADCY4 ADCY4 ENSTTRP00000007871 ENSTTRP00000007871 PRKCA PRKCA MYLK2 MYLK2 CAMK2B CAMK2B GNAI2 GNAI2 KCNE2 KCNE2 ITPR3 ITPR3 CCKBR CCKBR GNAI1 GNAI1 ACTG1 ACTG1 CA2 CA2 ATP1B1 ATP1B1 KCNJ1 KCNJ1 SSTR2 SSTR2 ATP4B ATP4B SLC26A7 SLC26A7 LRRC69 LRRC69 OTUD6B OTUD6B ADCY2 ADCY2 MYLK4 MYLK4 ITPR2 ITPR2 CALM3 CALM3 KCNJ2 KCNJ2 KCNJ16 KCNJ16 ATP1B4 ATP1B4 ADCY9 ADCY9 PRKCB PRKCB ACTB ACTB ATP1A4 ATP1A4 ATP1A2 ATP1A2 KCNJ10 KCNJ10 GNAI3 GNAI3 ENSTTRP00000001169 ENSTTRP00000001169 OTUD6A OTUD6A CAMK2D CAMK2D SLC4A2 SLC4A2 MYLK MYLK ADCY5 ADCY5 HRH2 HRH2 SLC9A1 SLC9A1 PLCB2 PLCB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (277 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
CALML4Calmodulin-like protein 4 isoform X2. (195 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
KCNJ15ATP-sensitive inward rectifier potassium channel 15. (375 aa)
ADCY3Adenylate cyclase type 3. (1141 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
ATP4APotassium-transporting ATPase alpha chain 1. (1034 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
ARSIArylsulfatase I. (571 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (539 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (364 aa)
ENSTTRP00000013721annotation not available (118 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
CALM1Calmodulin; Belongs to the calmodulin family. (149 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
ADCY7Adenylate cyclase type 7-like. (1080 aa)
ADCY1Adenylate cyclase 1. (1088 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1. (673 aa)
SSTSomatostatin. (116 aa)
KCNK10Potassium channel subfamily K member 10 isoform X2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (538 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5. (535 aa)
CALM2Calmodulin 2. (148 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
EZREzrin isoform X1. (582 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
ADCY6Adenylate cyclase 6. (1167 aa)
CALML6Calmodulin-like protein 6. (179 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (796 aa)
PRKCGProtein kinase C gamma type. (697 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
ATP1B2ATPase Na+/K+ transporting subunit beta 2. (290 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
KCNK2Potassium channel subfamily K member 2 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (426 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
ADCY4Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
ENSTTRP00000007871annotation not available (1012 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
MYLK2Myosin light chain kinase 2. (597 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (489 aa)
GNAI2G protein subunit alpha i2. (351 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
CCKBRGastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (449 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (284 aa)
KCNJ1ATP-sensitive inward rectifier potassium channel 1 isoform X1. (389 aa)
SSTR2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
SLC26A7Anion exchange transporter. (643 aa)
LRRC69Leucine rich repeat containing 69. (190 aa)
OTUD6BLOW QUALITY PROTEIN: OTU domain-containing protein 6B. (322 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
MYLK4Myosin light chain kinase family member 4. (388 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
CALM3Calmodulin 3. (148 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
KCNJ16Inward rectifier potassium channel 16 isoform X1. (370 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ACTBActin beta. (375 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1009 aa)
ATP1A2ATPase Na+/K+ transporting subunit alpha 2. (1020 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ENSTTRP00000001169annotation not available (170 aa)
OTUD6AOTU domain-containing protein 6A. (291 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily. (498 aa)
SLC4A2Anion exchange protein. (1182 aa)
MYLKMyosin light chain kinase. (1911 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (395 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
PLCB2Phosphoinositide phospholipase C. (1184 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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