99 items (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RHOA	Transforming protein RhoA. (193 aa)
	PLA2G2C	Phospholipase A2 group IIC. (143 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
	SLC12A2	Solute carrier family 12 member 2. (960 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1208 aa)
	PLA2G12A	Group XIIA secretory phospholipase A2. (182 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
	LOC101331433	LOW QUALITY PROTEIN: chymotrypsin-like elastase family member 2A; Belongs to the peptidase S1 family. (302 aa)
	CTRC	chymotrypsin-C; Belongs to the peptidase S1 family. (268 aa)
	RAP1B	Ras-related protein Rap-1b. (184 aa)
	OVCH1	Ovochymase-1; Belongs to the peptidase S1 family. (928 aa)
	ADCY3	Adenylate cyclase type 3. (1141 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
	ATP2A2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1041 aa)
	CTRB1	Chymotrypsinogen B. (263 aa)
	RAB8A	Ras-related protein Rab-8A. (207 aa)
	LOC101328382	Alpha-amylase. (511 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
	CEL	Carboxyl ester lipase. (614 aa)
	PLCB4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
	CELA1	Chymotrypsin like elastase 1. (252 aa)
	PRSS2	LOW QUALITY PROTEIN: trypsin-2; Belongs to the peptidase S1 family. (231 aa)
	ADCY8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
	ADCY7	Adenylate cyclase type 7-like. (1080 aa)
	ADCY1	Adenylate cyclase 1. (1088 aa)
	LOC101328668	Trypsin-like; Belongs to the peptidase S1 family. (148 aa)
	KCNQ1	Potassium voltage-gated channel subfamily KQT member 1. (673 aa)
	BST1	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 isoform X6. (271 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (277 aa)
	RAB11A	Ras-related protein Rab-11A. (215 aa)
	LOC101322020	Two pore calcium channel protein 2. (750 aa)
	ATP2B3	ATPase plasma membrane Ca2+ transporting 3. (1218 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
	CPA4	LOW QUALITY PROTEIN: carboxypeptidase A4. (421 aa)
	CPA2	LOW QUALITY PROTEIN: carboxypeptidase A2. (401 aa)
	ADCY6	Adenylate cyclase 6. (1167 aa)
	PRKCG	Protein kinase C gamma type. (697 aa)
	CLCA4	LOW QUALITY PROTEIN: calcium-activated chloride channel regulator 4. (898 aa)
	PLCB3	Phosphoinositide phospholipase C. (1230 aa)
	PLA2G3	Phospholipase A2 group III. (505 aa)
	ATP1B2	ATPase Na+/K+ transporting subunit beta 2. (290 aa)
	TRPC1	Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
	PRSS37	Probable inactive serine protease 37 isoform X1. (235 aa)
	PLA2G12B	Group XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
	CTRL	Chymotrypsin like. (260 aa)
	CCKAR	Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
	ADCY4	Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
	RYR2	Ryanodine receptor 2. (4945 aa)
	RAB27A	Ras-related protein Rab-27A. (221 aa)
	SLC4A4	Anion exchange protein. (1064 aa)
	ENSTTRP00000007871	annotation not available (1012 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
	RAB27B	Ras-related protein Rab-27B isoform X3. (217 aa)
	ATP2A1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1050 aa)
	SCTR	Secretin receptor. (428 aa)
	PLA2G5	Phospholipase A(2). (124 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
	SLC26A3	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (727 aa)
	ATP2B1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1217 aa)
	CCK	Cholecystokinin. (115 aa)
	ATP2A3	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1060 aa)
	CA2	Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (284 aa)
	PLA2G1B	Phospholipase A(2). (148 aa)
	LOC101317068	Chymotrypsin-like elastase family member 3B isoform X2; Belongs to the peptidase S1 family. (269 aa)
	RAP1A	Ras-related protein Rap-1A isoform X1. (184 aa)
	RAC1	Ras-related C3 botulinum toxin substrate 1 isoform X1. (199 aa)
	PLA2G2E	Phospholipase A(2). (142 aa)
	ATP2B2	ATPase plasma membrane Ca2+ transporting 2. (1243 aa)
	ADCY2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
	CPB2	Carboxypeptidase B2. (402 aa)
	CPA3	LOW QUALITY PROTEIN: mast cell carboxypeptidase A. (413 aa)
	CPB1	Carboxypeptidase B. (417 aa)
	ENSTTRP00000002833	annotation not available (131 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
	PLA2G10	Phospholipase A(2). (128 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
	CPA1	Carboxypeptidase A1. (418 aa)
	CD38	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (219 aa)
	KCNMA1	Calcium-activated potassium channel subunit alpha-1 isoform X1. (1173 aa)
	OVCH2	LOW QUALITY PROTEIN: ovochymase-2; Belongs to the peptidase S1 family. (548 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1009 aa)
	ATP1A2	ATPase Na+/K+ transporting subunit alpha 2. (1020 aa)
	RAB3D	RAB3D, member RAS oncogene family. (219 aa)
	ENSTTRP00000001139	annotation not available (235 aa)
	SLC4A2	Anion exchange protein. (1182 aa)
	ADCY5	Adenylate cyclase 5. (1263 aa)
	PNLIPRP2	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (466 aa)
	PNLIPRP1	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (448 aa)
	PNLIP	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (465 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
	PLCB2	Phosphoinositide phospholipase C. (1184 aa)
	CLCA2	Calcium-activated chloride channel regulator 2 isoform X1. (943 aa)
	CLCA1	Calcium-activated chloride channel regulator 1. (912 aa)
	CPA6	Carboxypeptidase A6. (438 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSTTRP00000012668	ENSTTRP00000004073	Adenylate cyclase 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.589
ADCY1	ADCY3	ENSTTRP00000012668	ENSTTRP00000014368	Adenylate cyclase 1.	Adenylate cyclase type 3.	0.891
ADCY1	ADCY4	ENSTTRP00000012668	ENSTTRP00000008190	Adenylate cyclase 1.	Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.584
ADCY1	ADCY5	ENSTTRP00000012668	ENSTTRP00000000558	Adenylate cyclase 1.	Adenylate cyclase 5.	0.577
ADCY1	ADCY6	ENSTTRP00000012668	ENSTTRP00000010703	Adenylate cyclase 1.	Adenylate cyclase 6.	0.577
ADCY1	ADCY7	ENSTTRP00000012668	ENSTTRP00000012692	Adenylate cyclase 1.	Adenylate cyclase type 7-like.	0.683
ADCY1	ADCY8	ENSTTRP00000012668	ENSTTRP00000012752	Adenylate cyclase 1.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.899
ADCY1	ADCY9	ENSTTRP00000012668	ENSTTRP00000002538	Adenylate cyclase 1.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.663
ADCY1	GNAS	ENSTTRP00000012668	ENSTTRP00000015134	Adenylate cyclase 1.	Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas.	0.934
ADCY1	PRKCA	ENSTTRP00000012668	ENSTTRP00000007685	Adenylate cyclase 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.862
ADCY1	PRKCB	ENSTTRP00000012668	ENSTTRP00000002526	Adenylate cyclase 1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.901
ADCY1	PRKCG	ENSTTRP00000012668	ENSTTRP00000010366	Adenylate cyclase 1.	Protein kinase C gamma type.	0.868
ADCY1	PTRHD1	ENSTTRP00000012668	ENSTTRP00000014343	Adenylate cyclase 1.	Putative peptidyl-tRNA hydrolase PTRHD1.	0.767
ADCY2	ADCY1	ENSTTRP00000004073	ENSTTRP00000012668	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 1.	0.589
ADCY2	ADCY4	ENSTTRP00000004073	ENSTTRP00000008190	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.565
ADCY2	ADCY5	ENSTTRP00000004073	ENSTTRP00000000558	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5.	0.999
ADCY2	ADCY6	ENSTTRP00000004073	ENSTTRP00000010703	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 6.	0.886
ADCY2	ADCY7	ENSTTRP00000004073	ENSTTRP00000012692	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7-like.	0.567
ADCY2	ADCY8	ENSTTRP00000004073	ENSTTRP00000012752	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.560
ADCY2	ADCY9	ENSTTRP00000004073	ENSTTRP00000002538	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.683