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| | PLCB2 | Phosphoinositide phospholipase C. (1184 aa) |
| | LOC109549807 | LOW QUALITY PROTEIN: uncharacterized protein LOC109549807. (169 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | ADCY5 | Adenylate cyclase 5. (1263 aa) |
| | AKT2 | RAC-beta serine/threonine-protein kinase. (481 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 1. (192 aa) |
| | BCAR1 | Breast cancer anti-estrogen resistance protein 1. (863 aa) |
| | BAX | Apoptosis regulator BAX. (198 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2442 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | GNB4 | Guanine nucleotide-binding protein subunit beta-4. (340 aa) |
| | RAC3 | Ras-related C3 botulinum toxin substrate 1 isoform X2. (192 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta. (735 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (574 aa) |
| | PTK2B | Protein-tyrosine kinase 2-beta isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (941 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (504 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | ADCY9 | Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa) |
| | AKAP13 | A-kinase anchor protein 13 isoform X1. (2803 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (560 aa) |
| | LPXN | Leupaxin isoform X2; Belongs to the paxillin family. (386 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1049 aa) |
| | GNG8 | G protein subunit gamma 8. (70 aa) |
| | CALM3 | Calmodulin 3. (148 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | CALR | Calreticulin. (417 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | STING1 | Stimulator of interferon genes protein isoform X1. (288 aa) |
| | GNA12 | Guanine nucleotide-binding protein subunit alpha-12. (382 aa) |
| | ENSTTRP00000003621 | annotation not available (129 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1303 aa) |
| | RB1 | Retinoblastoma-associated protein. (922 aa) |
| | TAP2 | Antigen peptide transporter 2 isoform X1. (484 aa) |
| | TAP1 | Antigen peptide transporter 1. (811 aa) |
| | TAPBP | Tapasin isoform X2. (497 aa) |
| | ADCY2 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | GNB5 | Guanine nucleotide-binding protein subunit beta-5. (395 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | RHEBL1 | GTPase RhebL1 isoform X2. (183 aa) |
| | CREB3L2 | LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1 isoform X1. (199 aa) |
| | IRF3 | Interferon regulatory factor 3. (438 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3. (382 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENSTTRP00000005342 | annotation not available (699 aa) |
| | SRC | Proto-oncogene tyrosine-protein kinase Src. (538 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa) |
| | LOC101330472 | C-C motif chemokine. (94 aa) |
| | LOC101330180 | C-C motif chemokine. (93 aa) |
| | CGAS | Cyclic GMP-AMP synthase isoform X1. (510 aa) |
| | LOC109551711 | C-C motif chemokine. (63 aa) |
| | ENSTTRP00000005523 | annotation not available (722 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | IL1R1 | Interleukin-1 receptor type 1 isoform X2. (572 aa) |
| | ATF6B | Activating transcription factor 6 beta. (671 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | ENSTTRP00000005802 | annotation not available (670 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | GNAI1 | Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | ENSTTRP00000006141 | annotation not available (161 aa) |
| | ENSTTRP00000006413 | annotation not available (364 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (212 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa) |
| | IKBKG | NF-kappa-B essential modulator. (424 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | STAT3 | Signal transducer and activator of transcription. (767 aa) |
| | GNAI2 | G protein subunit alpha i2. (351 aa) |
| | NFATC2 | Nuclear factor of activated T-cells, cytoplasmic 2 isoform X2. (919 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | PTGER1 | Prostaglandin E receptor 1. (408 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X2. (350 aa) |
| | LOC109552729 | H-2 class I histocompatibility antigen, alpha chain-like. (286 aa) |
| | LOC109549914 | Interferon alpha-4-like. (189 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (838 aa) |
| | CDK4 | Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (254 aa) |
| | CXCL12 | Stromal cell-derived factor 1 isoform X5; Belongs to the intercrine alpha (chemokine CxC) family. (138 aa) |
| | ADCY4 | Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (746 aa) |
| | GNAQ | Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa) |
| | CASP8 | Caspase-8 isoform X2; Belongs to the peptidase C14A family. (491 aa) |
| | IL10RA | Interleukin-10 receptor subunit alpha isoform X2. (579 aa) |
| | VEGFA | Vascular endothelial growth factor A. (402 aa) |
| | E2F3 | Transcription factor E2F3. (334 aa) |
| | IL6 | Interleukin-6. (208 aa) |
| | CRKL | Crk-like protein. (303 aa) |
| | GNA13 | Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (282 aa) |
| | SP1 | Transcription factor Sp1. (784 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | PTK2 | Focal adhesion kinase 1 isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1062 aa) |
| | IL10RB | Interleukin-10 receptor subunit beta isoform X1. (325 aa) |
| | ELK1 | ETS domain-containing protein Elk-1 isoform X2. (469 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (395 aa) |
| | E2F1 | Transcription factor E2F1 isoform X1. (437 aa) |
| | CREB3L3 | Cyclic AMP-responsive element-binding protein 3-like protein 3. (455 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1. (393 aa) |
| | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (262 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | PLCB3 | Phosphoinositide phospholipase C. (1230 aa) |
| | PTGER2 | Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | ENSTTRP00000010130 | annotation not available (118 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (484 aa) |
| | PRKCG | Protein kinase C gamma type. (697 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (265 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | CREB3L4 | Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X3. (395 aa) |
| | CALML6 | Calmodulin-like protein 6. (179 aa) |
| | ADCY6 | Adenylate cyclase 6. (1167 aa) |
| | PRKACB | cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12 isoform X1. (1542 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | CREB3 | Cyclic AMP-responsive element-binding protein 3. (365 aa) |
| | CALM2 | Calmodulin 2. (148 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (603 aa) |
| | GNA11 | G protein subunit alpha 11. (359 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1040 aa) |
| | ITGAV | Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1095 aa) |
| | KRAS | GTPase KRas. (189 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (535 aa) |
| | RUFY4 | RUN and FYVE domain-containing protein 4. (606 aa) |
| | ENSTTRP00000012198 | annotation not available (354 aa) |
| | ROCK2 | Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1378 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | RPS6KB2 | Non-specific serine/threonine protein kinase. (486 aa) |
| | ADCY1 | Adenylate cyclase 1. (1088 aa) |
| | ADCY7 | Adenylate cyclase type 7-like. (1080 aa) |
| | ADCY8 | Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa) |
| | GNAO1 | G protein subunit alpha o1. (354 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (783 aa) |
| | CALM1 | Calmodulin; Belongs to the calmodulin family. (149 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa) |
| | IL6R | Interleukin-6 receptor subunit alpha isoform X2. (466 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | AKT1 | AKT serine/threonine kinase 1. (480 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1304 aa) |
| | MAPK14 | Mitogen-activated protein kinase 14. (360 aa) |
| | TSC1 | Hamartin isoform X1. (1168 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (156 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (439 aa) |
| | ENSTTRP00000013721 | annotation not available (118 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11 isoform X2. (1548 aa) |
| | ATF4 | Cyclic AMP-dependent transcription factor ATF-4. (351 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3. (1071 aa) |
| | PTGER3 | Prostaglandin E2 receptor EP3 subtype isoform X2. (448 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha. (351 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (53 aa) |
| | PTRHD1 | Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa) |
| | ADCY3 | Adenylate cyclase type 3. (1141 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (152 aa) |
| | CSDE1 | Cold shock domain-containing protein E1. (813 aa) |
| | TSC2 | Tuberin. (1815 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (495 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (365 aa) |
| | ENSTTRP00000015100 | annotation not available (189 aa) |
| | GNAS | Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa) |
| | CALML4 | Calmodulin-like protein 4 isoform X2. (195 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa) |
| | E2F2 | Transcription factor E2F2 isoform X1. (433 aa) |
| | ENSTTRP00000015348 | annotation not available (321 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (732 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1. (904 aa) |
| | CRK | Adapter molecule crk isoform X4. (223 aa) |
| | ENSTTRP00000015784 | annotation not available (149 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (433 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1 isoform X1. (729 aa) |
| | RHEB | GTP-binding protein Rheb. (166 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1211 aa) |
| | CCR5 | C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | ENSTTRP00000016529 | annotation not available (169 aa) |
