STRINGSTRING
MYH3 MYH3 CACNA2D1 CACNA2D1 ITGA2 ITGA2 LAMA2 LAMA2 LMNA LMNA TNNT2 TNNT2 PRKAB1 PRKAB1 ACE ACE ITGA1 ITGA1 ACTB ACTB LRRC66 LRRC66 SGCB SGCB SLC8A2 SLC8A2 CACNG3 CACNG3 DAG1 DAG1 ITGB7 ITGB7 CACNA2D4 CACNA2D4 CACNA1C CACNA1C LAMA1 LAMA1 TPM1 TPM1 PRKAA2 PRKAA2 ITGA8 ITGA8 AGT AGT ITGA5 ITGA5 PRKAG1 PRKAG1 TNNT3 TNNT3 TTN TTN SGCD SGCD ITGA3 ITGA3 ITGA9 ITGA9 SGCA SGCA DMD DMD ATP2A3 ATP2A3 EDN1 EDN1 ACTG1 ACTG1 CACNG2 CACNG2 CACNB1 CACNB1 CACNA2D2 CACNA2D2 CACNB2 CACNB2 ATP2A1 ATP2A1 CACNG5 CACNG5 MYH8 MYH8 TNNC1 TNNC1 RYR2 RYR2 IL6 IL6 ITGA10 ITGA10 ITGA7 ITGA7 ITGB1 ITGB1 PRKAG3 PRKAG3 UTRN UTRN PRKAB2 PRKAB2 SLC8A1 SLC8A1 ITGA2B ITGA2B MYH6 MYH6 MYH7 MYH7 PRKAA1 PRKAA1 CACNG7 CACNG7 ITGB6 ITGB6 SGCG SGCG ITGA6 ITGA6 DES DES TPM2 TPM2 MYH15 MYH15 CACNA1D CACNA1D ITGAV ITGAV TGFB1 TGFB1 CACNG6 CACNG6 SLC39A12 SLC39A12 ITGB3 ITGB3 TGFB2 TGFB2 CACNA1S CACNA1S EMD EMD TNF TNF MYBPC3 MYBPC3 TPM4 TPM4 ACTL8 ACTL8 ATP2A2 ATP2A2 SLC8A3 SLC8A3 ACTC1 ACTC1 MYL2 MYL2 ITGB5 ITGB5 ITGB8 ITGB8 TGFB3 TGFB3 CACNB4 CACNB4 TNNT1 TNNT1 TNNI3 TNNI3 MYH1 MYH1 LOC109548408 LOC109548408 TPM3 TPM3 MYL3 MYL3 ITGB4 ITGB4 ITGA11 ITGA11 ITGA4 ITGA4 CACNG4 CACNG4 CACNG1 CACNG1 CACNA1F CACNA1F PRKAG2 PRKAG2 IGF1 IGF1 CACNA2D3 CACNA2D3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYH3Myosin-3 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1934 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (1106 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1178 aa)
LAMA2Laminin subunit alpha-2. (3120 aa)
LMNALamin A/C. (664 aa)
TNNT2Troponin T, cardiac muscle. (283 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1 isoform X2. (270 aa)
ACEAngiotensin-converting enzyme. (1308 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
ACTBActin beta. (375 aa)
LRRC66Leucine-rich repeat-containing protein 66 isoform X2. (857 aa)
SGCBBeta-sarcoglycan. (318 aa)
SLC8A2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (920 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit. (315 aa)
DAG1Dystroglycan. (892 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (789 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1133 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha-1C-like. (2195 aa)
LAMA1Laminin subunit alpha-1. (3051 aa)
TPM1Tropomyosin alpha-1 chain isoform X14; Belongs to the tropomyosin family. (326 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
ITGA8Integrin alpha-8; Belongs to the integrin alpha chain family. (1060 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
ITGA5Integrin subunit alpha 5. (1053 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X2. (356 aa)
TNNT3Troponin T3, fast skeletal type. (254 aa)
TTNLOW QUALITY PROTEIN: titin. (31921 aa)
SGCDDelta-sarcoglycan. (289 aa)
ITGA3Integrin subunit alpha 3. (1068 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (1034 aa)
SGCASarcoglycan alpha. (387 aa)
DMDDystrophin. (3674 aa)
ATP2A3Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1060 aa)
EDN1Endothelin-1. (202 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CACNB1Voltage-dependent L-type calcium channel subunit beta-1-like. (593 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1150 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (656 aa)
ATP2A1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1050 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (284 aa)
MYH8Myosin-8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1855 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
RYR2Ryanodine receptor 2. (4945 aa)
IL6Interleukin-6. (208 aa)
ITGA10Integrin alpha-10 isoform X1; Belongs to the integrin alpha chain family. (1166 aa)
ITGA7Integrin subunit alpha 7. (1180 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (786 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (486 aa)
UTRNUtrophin isoform X7. (3432 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (247 aa)
SLC8A1Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (972 aa)
ITGA2BIntegrin alpha-IIb. (1034 aa)
MYH6Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1934 aa)
MYH7Myosin-7-like. (1896 aa)
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)
CACNG7Calcium voltage-gated channel auxiliary subunit gamma 7. (273 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SGCGGamma-sarcoglycan. (291 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1130 aa)
DESDesmin; Belongs to the intermediate filament family. (461 aa)
TPM2Tropomyosin 2. (320 aa)
MYH15LOW QUALITY PROTEIN: myosin-15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1872 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
ITGAVIntegrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1095 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit. (254 aa)
SLC39A12Zinc transporter ZIP12 isoform X1. (690 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (783 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha-1S-like. (1856 aa)
EMDEmerin isoform X2. (255 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
MYBPC3Myosin binding protein C, cardiac. (1266 aa)
TPM4Tropomyosin alpha-4 chain; Belongs to the tropomyosin family. (284 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (364 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1041 aa)
SLC8A3Sodium/calcium exchanger 3 isoform X2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (920 aa)
ACTC1Actin alpha cardiac muscle 1. (376 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (782 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (765 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4. (520 aa)
TNNT1Troponin T, slow skeletal muscle. (268 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
MYH1LOW QUALITY PROTEIN: myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1807 aa)
LOC109548408Myosin-6. (1937 aa)
TPM3Tropomyosin alpha-3 chain isoform X2; Belongs to the tropomyosin family. (285 aa)
MYL3Myosin light chain 3. (197 aa)
ITGB4Integrin beta-4. (1815 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1218 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1037 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (178 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha-1F isoform X1. (1973 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (568 aa)
IGF1Insulin-like growth factor 1 transcript variant X4. (194 aa)
CACNA2D3Voltage-dependent calcium channel subunit alpha-2/delta-3. (1089 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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