STRINGSTRING
AFM AFM HHIP HHIP STAB2 STAB2 CLDN5 CLDN5 CSGALNACT2 CSGALNACT2 TJP1 TJP1 NTAN1 NTAN1 DGKE DGKE ICAM1 ICAM1 LOC111166170 LOC111166170 JUP JUP CCR7 CCR7 LYVE1 LYVE1 SELE SELE SELL SELL VEGFD VEGFD LOC111167918 LOC111167918 ARHGEF38 ARHGEF38 BMPR2 BMPR2 ENTPD1 ENTPD1 FLT4 FLT4 TACC2 TACC2 VEGFC VEGFC FN1 FN1 FAM124B FAM124B ATF7 ATF7 TIE1 TIE1 SKIL SKIL EFNB2 EFNB2 ARNTL2 ARNTL2 VEGFA VEGFA PDSS1 PDSS1 VWF VWF DNAJC13 DNAJC13 ITGA10 ITGA10 LIPG LIPG IL1B IL1B CSDE1 CSDE1 NPHS1 NPHS1 VCAM1 VCAM1 CDH5 CDH5 RXFP1 RXFP1 ERN1 ERN1 EPHB4 EPHB4 LOC111182630 LOC111182630 EDN1 EDN1 PECAM1 PECAM1 FADD FADD ECSCR ECSCR CHST1 CHST1 LOC111184729 LOC111184729 P4HA3 P4HA3 SDC4 SDC4 IL6 IL6 LAMC1 LAMC1 THBD THBD GOLGA3 GOLGA3 ASGR1 ASGR1 SCD5 SCD5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFMAfamin isoform X1. (616 aa)
HHIPHedgehog-interacting protein isoform X1. (700 aa)
STAB2Stabilin-2 isoform X1. (2663 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
CSGALNACT2Hexosyltransferase. (542 aa)
TJP1Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1914 aa)
NTAN1Protein N-terminal asparagine amidohydrolase isoform X1. (310 aa)
DGKEDiacylglycerol kinase. (578 aa)
ICAM1Intercellular adhesion molecule 1. (536 aa)
LOC111166170C-type lectin domain family 4 member G-like isoform X1. (313 aa)
JUPJunction plakoglobin. (744 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
LYVE1Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X1. (322 aa)
SELEE-selectin. (531 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (372 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
LOC111167918LOW QUALITY PROTEIN: gastrokine-3-like. (204 aa)
ARHGEF38Rho guanine nucleotide exchange factor 38 isoform X1. (779 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (527 aa)
FLT4Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
TACC2Transforming acidic coiled-coil-containing protein 2 isoform X6. (1026 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
FN1Fibronectin isoform X5. (2478 aa)
FAM124BProtein FAM124B. (462 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (483 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
SKILSki-like protein isoform X1. (684 aa)
EFNB2ephrin-B2; Belongs to the ephrin family. (333 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1. (607 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
PDSS1Decaprenyl-diphosphate synthase subunit 1 isoform X1; Belongs to the FPP/GGPP synthase family. (413 aa)
VWFVon Willebrand factor. (2806 aa)
DNAJC13dnaJ homolog subfamily C member 13 isoform X1. (2248 aa)
ITGA10Integrin alpha-10; Belongs to the integrin alpha chain family. (1167 aa)
LIPGEndothelial lipase. (505 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
NPHS1Nephrin. (1270 aa)
VCAM1Vascular cell adhesion protein 1. (739 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
RXFP1Relaxin receptor 1 isoform X1. (785 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
EDN1Endothelin-1. (202 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
ECSCREndothelial cell-specific chemotaxis regulator isoform X5. (203 aa)
CHST1Sulfotransferase; Belongs to the sulfotransferase 1 family. (411 aa)
LOC111184729Membrane cofactor protein-like isoform X1. (411 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha-3. (544 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
THBDThrombomodulin. (584 aa)
GOLGA3Golgin subfamily A member 3 isoform X1. (1497 aa)
ASGR1Asialoglycoprotein receptor 1 isoform X1. (469 aa)
SCD5stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (334 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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