STRINGSTRING
LOC111167918 LOC111167918 ESS2 ESS2 CLDN5 CLDN5 ACTBL2 ACTBL2 CDC42 CDC42 ACTL8 ACTL8 GP2 GP2 AUNIP AUNIP NBL1 NBL1 TMPRSS2 TMPRSS2 AGT AGT TFF3 TFF3 CSGALNACT2 CSGALNACT2 FHL1 FHL1 TJP1 TJP1 ZNF385D ZNF385D NTAN1 NTAN1 DGKE DGKE ATOH8 ATOH8 HAUS4 HAUS4 SIAH1 SIAH1 PSMB11 PSMB11 NPHS2 NPHS2 TAS1R2 TAS1R2 IL13RA2 IL13RA2 ICAM1 ICAM1 LOC111166170 LOC111166170 EYA4 EYA4 GRINA GRINA JUP JUP CCR7 CCR7 LOC111166411 LOC111166411 FBN3 FBN3 STAT3 STAT3 KCNS3 KCNS3 LOC111167004 LOC111167004 MMP2 MMP2 CFAP45 CFAP45 LOC111167137 LOC111167137 LOC111167162 LOC111167162 CLCN4 CLCN4 GJA1 GJA1 ESR1 ESR1 LYVE1 LYVE1 NES NES LOC111167138 LOC111167138 LOC111167146 LOC111167146 ERBB2 ERBB2 TMEM11 TMEM11 MMP20 MMP20 SLC5A10 SLC5A10 ANXA4 ANXA4 AR AR TPO TPO CNGA2 CNGA2 PGR PGR S100A5 S100A5 LOC111167154 LOC111167154 CSN2 CSN2 AIG1 AIG1 ACE2 ACE2 JUND JUND LOC111169204 LOC111169204 SELE SELE UPK2 UPK2 LOC111168748 LOC111168748 LOC111168862 LOC111168862 TMEM27 TMEM27 CGN CGN PAQR6 PAQR6 ABHD2 ABHD2 SELL SELL GFAP GFAP CHEK1 CHEK1 ACTB ACTB HIGD2A HIGD2A VEGFD VEGFD ZNF335 ZNF335 GKN1 GKN1 ABCD1 ABCD1 ARHGEF38 ARHGEF38 SHISA3 SHISA3 RLBP1 RLBP1 S100A10 S100A10 BMPR2 BMPR2 RHO RHO MUC13 MUC13 CNGA4 CNGA4 SLC51A SLC51A GPBAR1 GPBAR1 ANPEP ANPEP ENTPD1 ENTPD1 LOC111172859 LOC111172859 GOLGB1 GOLGB1 NET1 NET1 EYA2 EYA2 CLDN1 CLDN1 EPC2 EPC2 LOC111173353 LOC111173353 LGR5 LGR5 FLT4 FLT4 TACC2 TACC2 KRT4 KRT4 LALBA LALBA VEGFC VEGFC TRAPPC11 TRAPPC11 CASP3 CASP3 TLR3 TLR3 ABCD2 ABCD2 FN1 FN1 FAM124B FAM124B NISCH NISCH KCNMB2 KCNMB2 GPX1 GPX1 KRT8 KRT8 KRT7 KRT7 ADCY3 ADCY3 PREB PREB PTRHD1 PTRHD1 TP63 TP63 ATF7 ATF7 KRT18 KRT18 KRT80 KRT80 SCAF11 SCAF11 EPCAM EPCAM VSX2 VSX2 PRKCH PRKCH TIE1 TIE1 LOC111175255 LOC111175255 TMEM53 TMEM53 ORMDL2 ORMDL2 SLC11A2 SLC11A2 SKIL SKIL LOC111175246 LOC111175246 POU4F1 POU4F1 TLR4 TLR4 EPB41L4B EPB41L4B EFNB2 EFNB2 KLF5 KLF5 ARNTL2 ARNTL2 VEGFA VEGFA CD2AP CD2AP GADD45A GADD45A PDSS1 PDSS1 ARHGEF26 ARHGEF26 VWF VWF GAPDH GAPDH RPE65 RPE65 HAS3 HAS3 DNAJC13 DNAJC13 SPDEF SPDEF CHIA CHIA ITGA10 ITGA10 OVGP1 OVGP1 CDH3 CDH3 DISP1 DISP1 LIPG LIPG CFTR CFTR CAV1 CAV1 PODXL PODXL CSDE1 CSDE1 NPHS1 NPHS1 CLDND1 CLDND1 VCAM1 VCAM1 CDH5 CDH5 RXFP1 RXFP1 DEPDC1 DEPDC1 TSEN34 TSEN34 LOC111180193 LOC111180193 KLK4 KLK4 KCNN4 KCNN4 FFAR2 FFAR2 PAX6 PAX6 SLC39A2 SLC39A2 DSP DSP CPSF4 CPSF4 AQP4 AQP4 IL11 IL11 MARVELD3 MARVELD3 LOC111181115 LOC111181115 ATP4A ATP4A HERPUD2 HERPUD2 WT1 WT1 GCNT2 GCNT2 PLCB2 PLCB2 GABPB1 GABPB1 NEUROG1 NEUROG1 ERN1 ERN1 NTF4 NTF4 KIF22 KIF22 FOXJ1 FOXJ1 EPHB4 EPHB4 UPK1A UPK1A HAMP HAMP PRL PRL LOC111182630 LOC111182630 LOC111181354 LOC111181354 FBN2 FBN2 EDN1 EDN1 ACTG1 ACTG1 DSG1 DSG1 CPSF4L CPSF4L KCNJ2 KCNJ2 CFL1 CFL1 ERCC3 ERCC3 POU4F3 POU4F3 KCNMA1 KCNMA1 SLC5A2 SLC5A2 PRSS36 PRSS36 PECAM1 PECAM1 FADD FADD B4GAT1 B4GAT1 ECSCR ECSCR CHST1 CHST1 PTPN14 PTPN14 LOC111184729 LOC111184729 SPINK5 SPINK5 SLCO4C1 SLCO4C1 P4HA3 P4HA3 SDC4 SDC4 SYNPO SYNPO KCNS1 KCNS1 REN REN IL10 IL10 FAM222B FAM222B OMP OMP BFSP1 BFSP1 MAP2K4 MAP2K4 NPC1L1 NPC1L1 CHIT1 CHIT1 LAMC1 LAMC1 FOXN1 FOXN1 GCNT7 GCNT7 PFDN4 PFDN4 ISM1 ISM1 THBD THBD AIRE AIRE RHBDL1 RHBDL1 ATP6V0C ATP6V0C NKX3-1 NKX3-1 ELOVL7 ELOVL7 SLCO4A1 SLCO4A1 KCNB1 KCNB1 GOLGA3 GOLGA3 ASGR1 ASGR1 MMP17 MMP17 NUP88 NUP88 ANXA5 ANXA5 TAS1R3 TAS1R3 IL36G IL36G SCD5 SCD5 AFM AFM DDX4 DDX4 AMBN AMBN AMTN AMTN IGF1 IGF1 STAB2 STAB2 GLIPR2 GLIPR2 PAX8 PAX8 INPP4B INPP4B HHIP HHIP POU4F2 POU4F2 TNF TNF IL1B IL1B CD4 CD4 IL6 IL6
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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LOC111167918LOW QUALITY PROTEIN: gastrokine-3-like. (204 aa)
ESS2Protein DGCR14. (478 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ACTBL2LOW QUALITY PROTEIN: beta-actin-like protein 2; Belongs to the actin family. (373 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
GP2Pancreatic secretory granule membrane major glycoprotein GP2. (530 aa)
AUNIPAurora kinase A and ninein-interacting protein. (357 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1 isoform X3. (214 aa)
TMPRSS2Transmembrane protease serine 2 isoform X4; Belongs to the peptidase S1 family. (528 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
TFF3Trefoil factor 3. (80 aa)
CSGALNACT2Hexosyltransferase. (542 aa)
FHL1Four and a half LIM domains protein 1 isoform X1. (339 aa)
TJP1Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1914 aa)
ZNF385DZinc finger protein 385D isoform X1. (395 aa)
NTAN1Protein N-terminal asparagine amidohydrolase isoform X1. (310 aa)
DGKEDiacylglycerol kinase. (578 aa)
ATOH8Protein atonal homolog 8 isoform X1. (354 aa)
HAUS4HAUS augmin-like complex subunit 4 isoform X1. (446 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
PSMB11Proteasome subunit beta. (291 aa)
NPHS2Podocin isoform X1. (383 aa)
TAS1R2LOW QUALITY PROTEIN: taste receptor type 1 member 2. (830 aa)
IL13RA2Interleukin-13 receptor subunit alpha-2. (387 aa)
ICAM1Intercellular adhesion molecule 1. (536 aa)
LOC111166170C-type lectin domain family 4 member G-like isoform X1. (313 aa)
EYA4Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (622 aa)
GRINAProtein lifeguard 1. (366 aa)
JUPJunction plakoglobin. (744 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
LOC111166411Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family. (400 aa)
FBN3Fibrillin-3 isoform X1. (2823 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
KCNS3Potassium voltage-gated channel subfamily S member 3; Belongs to the potassium channel family. (491 aa)
LOC111167004LOW QUALITY PROTEIN: peptidoglycan recognition protein 3-like. (277 aa)
MMP272 kDa type IV collagenase. (661 aa)
CFAP45Cilia- and flagella-associated protein 45. (466 aa)
LOC111167137LOW QUALITY PROTEIN: putative olfactory receptor 10J6. (476 aa)
LOC111167162Olfactory receptor 10K1-like. (301 aa)
CLCN4Chloride channel protein. (606 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
LYVE1Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X1. (322 aa)
NESNestin; Belongs to the intermediate filament family. (1570 aa)
LOC111167138LOW QUALITY PROTEIN: olfactory receptor 10J5-like. (299 aa)
LOC111167146Olfactory receptor 10K1. (315 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
TMEM11Transmembrane protein 11, mitochondrial isoform X1. (199 aa)
MMP20Matrix metalloproteinase-20. (483 aa)
SLC5A10Sodium/glucose cotransporter 5 isoform X3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (540 aa)
ANXA4Annexin. (319 aa)
ARAndrogen receptor. (893 aa)
TPOThyroid peroxidase. (870 aa)
CNGA2LOW QUALITY PROTEIN: cyclic nucleotide-gated olfactory channel. (512 aa)
PGRProgesterone receptor. (936 aa)
S100A5Protein S100-A5. (112 aa)
LOC111167154LOW QUALITY PROTEIN: olfactory receptor 10K2-like. (307 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles; Belongs to the beta-casein family. (239 aa)
AIG1Androgen-induced gene 1 protein isoform X7. (281 aa)
ACE2Angiotensin-converting enzyme. (804 aa)
JUNDTranscription factor jun-D. (345 aa)
LOC111169204Olfactory receptor 10J4-like. (270 aa)
SELEE-selectin. (531 aa)
UPK2Uroplakin-2. (185 aa)
LOC111168748Annexin. (327 aa)
LOC111168862Keratin, type II cytoskeletal 8-like; Belongs to the intermediate filament family. (486 aa)
TMEM27Collectrin isoform X2. (222 aa)
CGNCingulin isoform X1. (1194 aa)
PAQR6Progestin and adipoQ receptor family member 6. (344 aa)
ABHD2Monoacylglycerol lipase ABHD2 isoform X1. (425 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (372 aa)
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (470 aa)
CHEK1Serine/threonine-protein kinase Chk1 isoform X1. (540 aa)
ACTBActin, cytoplasmic 1. (375 aa)
HIGD2AHIG1 domain family member 2A, mitochondrial. (106 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
ZNF335Zinc finger protein 335 isoform X1. (1346 aa)
GKN1Gastrokine-1. (184 aa)
ABCD1ATP-binding cassette sub-family D member 1 isoform X1. (774 aa)
ARHGEF38Rho guanine nucleotide exchange factor 38 isoform X1. (779 aa)
SHISA3Protein shisa-3 homolog. (238 aa)
RLBP1Retinaldehyde-binding protein 1. (317 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (96 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
RHORhodopsin. (348 aa)
MUC13Mucin-13. (397 aa)
CNGA4Cyclic nucleotide-gated cation channel alpha-4. (592 aa)
SLC51AOrganic solute transporter subunit alpha. (347 aa)
GPBAR1G-protein coupled bile acid receptor 1. (329 aa)
ANPEPAminopeptidase. (969 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (527 aa)
LOC111172859Cytochrome b reductase 1 isoform X1. (285 aa)
GOLGB1Golgin subfamily B member 1 isoform X1. (3275 aa)
NET1Neuroepithelial cell-transforming gene 1 protein isoform X1. (596 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (549 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
LOC111173353Beta-defensin 103A-like. (67 aa)
LGR5Leucine-rich repeat-containing G-protein coupled receptor 5. (907 aa)
FLT4Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
TACC2Transforming acidic coiled-coil-containing protein 2 isoform X6. (1026 aa)
KRT4Keratin, type II cytoskeletal 4; Belongs to the intermediate filament family. (519 aa)
LALBAAlpha-lactalbumin; Belongs to the glycosyl hydrolase 22 family. (141 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
TRAPPC11Trafficking protein particle complex subunit 11 isoform X1. (1133 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
ABCD2ATP-binding cassette sub-family D member 2. (741 aa)
FN1Fibronectin isoform X5. (2478 aa)
FAM124BProtein FAM124B. (462 aa)
NISCHNischarin isoform X1. (1513 aa)
KCNMB2Calcium-activated potassium channel subunit beta-2. (235 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (206 aa)
KRT8Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (489 aa)
KRT7Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family. (467 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1150 aa)
PREBProlactin regulatory element-binding protein isoform X1. (417 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (483 aa)
KRT18Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (429 aa)
KRT80Keratin, type II cytoskeletal 80; Belongs to the intermediate filament family. (452 aa)
SCAF11Protein SCAF11 isoform X1. (1458 aa)
EPCAMEpithelial cell adhesion molecule. (314 aa)
VSX2Visual system homeobox 2. (361 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
LOC111175255Dolichyl-phosphate beta-glucosyltransferase-like isoform X1. (158 aa)
TMEM53Transmembrane protein 53 isoform X1. (278 aa)
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
SLC11A2Natural resistance-associated macrophage protein 2 isoform X1. (579 aa)
SKILSki-like protein isoform X1. (684 aa)
LOC111175246Dolichyl-phosphate beta-glucosyltransferase isoform X1. (324 aa)
POU4F1POU domain protein. (422 aa)
TLR4Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa)
EPB41L4BBand 4.1-like protein 4B isoform X1. (901 aa)
EFNB2ephrin-B2; Belongs to the ephrin family. (333 aa)
KLF5Krueppel-like factor 5. (454 aa)
ARNTL2Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1. (607 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
CD2APCD2-associated protein isoform X1. (680 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa)
PDSS1Decaprenyl-diphosphate synthase subunit 1 isoform X1; Belongs to the FPP/GGPP synthase family. (413 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (870 aa)
VWFVon Willebrand factor. (2806 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
RPE65Retinoid isomerohydrolase. (533 aa)
HAS3Hyaluronan synthase 3. (553 aa)
DNAJC13dnaJ homolog subfamily C member 13 isoform X1. (2248 aa)
SPDEFSAM pointed domain-containing Ets transcription factor. (337 aa)
CHIAAcidic mammalian chitinase isoform X1; Belongs to the glycosyl hydrolase 18 family. (474 aa)
ITGA10Integrin alpha-10; Belongs to the integrin alpha chain family. (1167 aa)
OVGP1LOW QUALITY PROTEIN: oviduct-specific glycoprotein; Belongs to the glycosyl hydrolase 18 family. (602 aa)
CDH3Cadherin-3 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (834 aa)
DISP1Protein dispatched homolog 1. (1532 aa)
LIPGEndothelial lipase. (505 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (532 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
NPHS1Nephrin. (1270 aa)
CLDND1Claudin domain-containing protein 1. (253 aa)
VCAM1Vascular cell adhesion protein 1. (739 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
RXFP1Relaxin receptor 1 isoform X1. (785 aa)
DEPDC1DEP domain-containing protein 1A isoform X2. (812 aa)
TSEN34tRNA-splicing endonuclease subunit Sen34 isoform X1. (315 aa)
LOC111180193Serpin B10; Belongs to the serpin family. (398 aa)
KLK4Kallikrein-4; Belongs to the peptidase S1 family. (254 aa)
KCNN4Intermediate conductance calcium-activated potassium channel protein 4. (428 aa)
FFAR2Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (329 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
SLC39A2Zinc transporter ZIP2 isoform X1. (306 aa)
DSPDesmoplakin isoform X1. (2874 aa)
CPSF4Cleavage and polyadenylation specificity factor subunit 4 isoform X1. (309 aa)
AQP4Aquaporin-4 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (338 aa)
IL11Interleukin-11. (199 aa)
MARVELD3MARVEL domain-containing protein 3. (384 aa)
LOC111181115Kallikrein-6-like isoform X1; Belongs to the peptidase S1 family. (247 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
HERPUD2annotation not available (406 aa)
WT1Wilms tumor protein isoform X1. (450 aa)
GCNT2N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase isoform X1. (419 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
GABPB1GA-binding protein subunit beta-1 isoform X1. (395 aa)
NEUROG1Neurogenin-1. (244 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (247 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (673 aa)
FOXJ1Forkhead box protein J1. (422 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
UPK1AUroplakin-1a isoform X1; Belongs to the tetraspanin (TM4SF) family. (313 aa)
HAMPHepcidin isoform X2. (108 aa)
PRLProlactin isoform X1. (230 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
LOC111181354N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase-like. (321 aa)
FBN2Fibrillin-2. (2912 aa)
EDN1Endothelin-1. (202 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
DSG1Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1039 aa)
CPSF4LPutative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X2. (198 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit isoform X1. (782 aa)
POU4F3POU domain protein. (338 aa)
KCNMA1LOW QUALITY PROTEIN: calcium-activated potassium channel subunit alpha-1. (1320 aa)
SLC5A2Sodium/glucose cotransporter 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa)
PRSS36Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family. (855 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
B4GAT1Beta-1,4-glucuronyltransferase 1. (415 aa)
ECSCREndothelial cell-specific chemotaxis regulator isoform X5. (203 aa)
CHST1Sulfotransferase; Belongs to the sulfotransferase 1 family. (411 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa)
LOC111184729Membrane cofactor protein-like isoform X1. (411 aa)
SPINK5Serine protease inhibitor Kazal-type 5. (841 aa)
SLCO4C1Solute carrier organic anion transporter family member. (724 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha-3. (544 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
SYNPOSynaptopodin isoform X1. (901 aa)
KCNS1Potassium voltage-gated channel subfamily S member 1; Belongs to the potassium channel family. (498 aa)
RENRenin isoform X1; Belongs to the peptidase A1 family. (401 aa)
IL10Interleukin-10. (178 aa)
FAM222BProtein FAM222B isoform X1. (564 aa)
OMPOlfactory marker protein. (229 aa)
BFSP1Filensin isoform X1. (593 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X4; Belongs to the protein kinase superfamily. (410 aa)
NPC1L1Niemann-Pick C1-like protein 1 isoform X1. (1331 aa)
CHIT1LOW QUALITY PROTEIN: chitotriosidase-1; Belongs to the glycosyl hydrolase 18 family. (467 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
FOXN1Forkhead box protein N1. (645 aa)
GCNT7beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 isoform X2. (429 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
ISM1Isthmin-1 isoform X1. (473 aa)
THBDThrombomodulin. (584 aa)
AIREAutoimmune regulator. (553 aa)
RHBDL1Rhomboid-related protein 1 isoform X1; Belongs to the peptidase S54 family. (373 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
NKX3-1Homeobox protein Nkx-3.1. (241 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
SLCO4A1Solute carrier organic anion transporter family member. (872 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
GOLGA3Golgin subfamily A member 3 isoform X1. (1497 aa)
ASGR1Asialoglycoprotein receptor 1 isoform X1. (469 aa)
MMP17Matrix metalloproteinase-17 isoform X1. (637 aa)
NUP88Nuclear pore complex protein Nup88 isoform X3. (743 aa)
ANXA5Annexin. (370 aa)
TAS1R3LOW QUALITY PROTEIN: taste receptor type 1 member 3. (841 aa)
IL36GInterleukin-1. (266 aa)
SCD5stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (334 aa)
AFMAfamin isoform X1. (616 aa)
DDX4Probable ATP-dependent RNA helicase DDX4; Belongs to the DEAD box helicase family. (728 aa)
AMBNAmeloblastin. (417 aa)
AMTNAmelotin. (189 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
STAB2Stabilin-2 isoform X1. (2663 aa)
GLIPR2Golgi-associated plant pathogenesis-related protein 1 isoform X1; Belongs to the CRISP family. (154 aa)
PAX8Paired box protein Pax-8. (457 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase isoform X2. (754 aa)
HHIPHedgehog-interacting protein isoform X1. (700 aa)
POU4F2POU domain protein. (407 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (455 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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