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| | ARHGEF38 | Rho guanine nucleotide exchange factor 38 isoform X1. (779 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa) |
| | ALB | Serum albumin. (607 aa) |
| | MRPL1 | 39S ribosomal protein L1, mitochondrial isoform X2. (328 aa) |
| | HHIP | Hedgehog-interacting protein isoform X1. (700 aa) |
| | ATP2A2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa) |
| | STAB2 | Stabilin-2 isoform X1. (2663 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (186 aa) |
| | SOX18 | Transcription factor SOX-18. (390 aa) |
| | C1QTNF3 | Complement C1q tumor necrosis factor-related protein 3 isoform X1. (319 aa) |
| | AFM | Afamin isoform X1. (616 aa) |
| | SCD5 | stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (334 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa) |
| | HCN1 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (876 aa) |
| | ASGR1 | Asialoglycoprotein receptor 1 isoform X1. (469 aa) |
| | GOLGA3 | Golgin subfamily A member 3 isoform X1. (1497 aa) |
| | TCTN1 | Tectonic-1 isoform X1. (590 aa) |
| | KCNMB1 | Calcium-activated potassium channel subunit beta-1. (191 aa) |
| | DIMT1 | rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (317 aa) |
| | THBD | Thrombomodulin. (584 aa) |
| | EEF1A2 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa) |
| | ATP2A3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1057 aa) |
| | P2RY2 | P2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | LAMC1 | Laminin subunit gamma-1. (1608 aa) |
| | CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa) |
| | PDE5A | Phosphodiesterase. (865 aa) |
| | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1. (542 aa) |
| | GFM2 | Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (776 aa) |
| | CD47 | Leukocyte surface antigen CD47 isoform X1. (329 aa) |
| | NOX4 | NADPH oxidase 4. (530 aa) |
| | CRISPLD1 | Cysteine-rich secretory protein LCCL domain-containing 1 isoform X1. (500 aa) |
| | INTS4 | Integrator complex subunit 4. (964 aa) |
| | REN | Renin isoform X1; Belongs to the peptidase A1 family. (401 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | WDR41 | WD repeat-containing protein 41 isoform X1. (458 aa) |
| | PDE8B | Phosphodiesterase. (885 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa) |
| | LOC111182954 | Angiotensin-converting enzyme. (199 aa) |
| | P4HA3 | Prolyl 4-hydroxylase subunit alpha-3. (544 aa) |
| | MYL9 | Myosin regulatory light polypeptide 9. (172 aa) |
| | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa) |
| | LOC111184729 | Membrane cofactor protein-like isoform X1. (411 aa) |
| | CHST1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (411 aa) |
| | HILPDA | LOW QUALITY PROTEIN: hypoxia-inducible lipid droplet-associated protein. (63 aa) |
| | ECSCR | Endothelial cell-specific chemotaxis regulator isoform X5. (203 aa) |
| | ANGPT4 | Angiopoietin-4. (498 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | PECAM1 | Platelet endothelial cell adhesion molecule isoform X1. (701 aa) |
| | SERPINE1 | Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily KQT member 1 isoform X1; Belongs to the potassium channel family. (673 aa) |
| | SPARC | SPARC. (303 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa) |
| | EEF1A1 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa) |
| | TMEM225B | LOW QUALITY PROTEIN: transmembrane protein 225B. (286 aa) |
| | FBN1 | Fibrillin-1 isoform X1. (2871 aa) |
| | TIMP2 | Metalloproteinase inhibitor 2. (220 aa) |
| | ACTG1 | Actin, cytoplasmic 2. (375 aa) |
| | GFOD1 | Glucose-fructose oxidoreductase domain-containing protein 1 isoform X1. (390 aa) |
| | EDN1 | Endothelin-1. (202 aa) |
| | LIN37 | Protein lin-37 homolog isoform X1. (246 aa) |
| | LOC111182630 | Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa) |
| | TFPI2 | Tissue factor pathway inhibitor. (300 aa) |
| | EPHB4 | Ephrin type-B receptor 4. (987 aa) |
| | EIF3K | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa) |
| | SYCN | Syncollin. (140 aa) |
| | ERN1 | Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa) |
| | ELN | Elastin isoform X1. (748 aa) |
| | GFOD2 | Glucose-fructose oxidoreductase domain-containing protein 2 isoform X1. (414 aa) |
| | PPP1R14A | Protein phosphatase 1 regulatory subunit 14A. (147 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | HOXA5 | Homeobox protein Hox-A5. (381 aa) |
| | LOC111179231 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (421 aa) |
| | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa) |
| | RXFP1 | Relaxin receptor 1 isoform X1. (785 aa) |
| | DEPDC7 | LOW QUALITY PROTEIN: DEP domain-containing protein 7. (511 aa) |
| | APOE | Apolipoprotein E. (316 aa) |
| | VCAM1 | Vascular cell adhesion protein 1. (739 aa) |
| | CSDE1 | Cold shock domain-containing protein E1 isoform X1. (798 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | CTHRC1 | Collagen triple helix repeat-containing protein 1. (285 aa) |
| | LIPG | Endothelial lipase. (505 aa) |
| | CAPN8 | LOW QUALITY PROTEIN: calpain-8; Belongs to the peptidase C2 family. (697 aa) |
| | ITGA10 | Integrin alpha-10; Belongs to the integrin alpha chain family. (1167 aa) |
| | PRRC2B | Protein PRRC2B isoform X1. (2229 aa) |
| | DNAJC13 | dnaJ homolog subfamily C member 13 isoform X1. (2248 aa) |
| | RSL24D1 | Probable ribosome biogenesis protein RLP24. (163 aa) |
| | RUNX2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (524 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | VWF | Von Willebrand factor. (2806 aa) |
| | ARMCX1 | Armadillo repeat-containing X-linked protein 1. (454 aa) |
| | LOC111178043 | LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like. (404 aa) |
| | PDSS1 | Decaprenyl-diphosphate synthase subunit 1 isoform X1; Belongs to the FPP/GGPP synthase family. (413 aa) |
| | TMEM255B | LOW QUALITY PROTEIN: transmembrane protein 255B. (329 aa) |
| | VEGFA | Vascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa) |
| | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1. (607 aa) |
| | CSK | Tyrosine-protein kinase. (528 aa) |
| | STOML1 | Stomatin-like protein 1 isoform X1. (463 aa) |
| | EFNB2 | ephrin-B2; Belongs to the ephrin family. (333 aa) |
| | HCN4 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (1201 aa) |
| | LOC111177107 | Protein PRRC2B-like isoform X1. (480 aa) |
| | CAPN2 | Calpain-2 catalytic subunit isoform X1; Belongs to the peptidase C2 family. (703 aa) |
| | APP | Amyloid beta A4 protein isoform X1. (767 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) |
| | SKIL | Ski-like protein isoform X1. (684 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | ORMDL2 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | COMMD6 | COMM domain-containing protein 6 isoform X1. (93 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | KCNK3 | Potassium channel subfamily K member. (398 aa) |
| | TIE1 | Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa) |
| | ATF7 | Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (483 aa) |
| | NME6 | Nucleoside diphosphate kinase. (186 aa) |
| | HMGA2 | High mobility group protein HMGI-C. (109 aa) |
| | ATP13A3 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1259 aa) |
| | POMK | Protein O-mannose kinase. (350 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (490 aa) |
| | FAM124B | Protein FAM124B. (462 aa) |
| | FN1 | Fibronectin isoform X5. (2478 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa) |
| | KLHDC1 | Kelch domain-containing protein 1 isoform X1. (406 aa) |
| | TACC2 | Transforming acidic coiled-coil-containing protein 2 isoform X6. (1026 aa) |
| | MYL6B | Myosin light chain 6B. (213 aa) |
| | FLT4 | Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa) |
| | PLAT | Plasminogen activator; Belongs to the peptidase S1 family. (565 aa) |
| | BGN | Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa) |
| | HCN2 | LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2. (904 aa) |
| | FAP | Prolyl endopeptidase FAP; Belongs to the peptidase S9B family. (783 aa) |
| | GCG | Glucagon isoform X1. (180 aa) |
| | VWA2 | LOW QUALITY PROTEIN: von Willebrand factor A domain-containing protein 2. (774 aa) |
| | SEC23IP | SEC23-interacting protein isoform X1. (1004 aa) |
| | ACTA2 | Actin, aortic smooth muscle. (466 aa) |
| | TCEANC | Transcription elongation factor A N-terminal and central domain-containing protein. (352 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (527 aa) |
| | COL6A3 | Collagen alpha-3(VI) chain isoform X1. (3229 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | CALCRL | Calcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa) |
| | LAS1L | Ribosomal biogenesis protein LAS1L isoform X1. (761 aa) |
| | TBC1D8B | TBC1 domain family member 8B isoform X1. (1120 aa) |
| | PGM2 | Phosphoglucomutase-2. (616 aa) |
| | LOC111167918 | LOW QUALITY PROTEIN: gastrokine-3-like. (204 aa) |
| | PDZD11 | PDZ domain-containing protein 11. (140 aa) |
| | DROSHA | Ribonuclease 3 isoform X1. (1414 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | ACTB | Actin, cytoplasmic 1. (375 aa) |
| | PGRMC1 | Membrane-associated progesterone receptor component 1; Belongs to the cytochrome b5 family. (194 aa) |
| | KCNN3 | Small conductance calcium-activated potassium channel protein 3 isoform X1. (722 aa) |
| | FAM13C | Protein FAM13C isoform X1. (625 aa) |
| | RGS5 | Regulator of G-protein signaling 5. (181 aa) |
| | SELE | E-selectin. (531 aa) |
| | POGK | Pogo transposable element with KRAB domain. (609 aa) |
| | SELP | P-selectin isoform X1. (768 aa) |
| | COL1A1 | Collagen alpha-1(I) chain. (1463 aa) |
| | LOC111167902 | Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa) |
| | MMP1 | Interstitial collagenase isoform X1. (554 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) |
| | MSTO1 | Protein misato homolog 1 isoform X1. (571 aa) |
| | LYVE1 | Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X1. (322 aa) |
| | GJA1 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa) |
| | SH2D2A | SH2 domain-containing protein 2A isoform X1. (449 aa) |
| | JUP | Junction plakoglobin. (744 aa) |
| | LOC111166170 | C-type lectin domain family 4 member G-like isoform X1. (313 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (536 aa) |
| | TCF21 | Transcription factor 21. (179 aa) |
| | MYB | Transcriptional activator Myb isoform X3. (761 aa) |
| | CTGF | Connective tissue growth factor isoform X1. (349 aa) |
| | COL22A1 | Collagen alpha-1(XXII) chain isoform X1. (1604 aa) |
| | KCNK9 | Potassium channel subfamily K member. (374 aa) |
| | GPIHBP1 | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1. (199 aa) |
| | LOC111163733 | C-C motif chemokine. (90 aa) |
| | DGKE | Diacylglycerol kinase. (578 aa) |
| | PDE8A | Phosphodiesterase. (657 aa) |
| | TJP1 | Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1914 aa) |
| | CSGALNACT2 | Hexosyltransferase. (542 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | SCPEP1 | Carboxypeptidase; Belongs to the peptidase S10 family. (470 aa) |
| | SDR39U1 | Epimerase family protein SDR39U1 isoform X1. (294 aa) |
| | LUM | Lumican. (340 aa) |
| | MYH11 | Myosin-11 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (477 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (360 aa) |
| | ACTL8 | Actin-like protein 8; Belongs to the actin family. (365 aa) |
| | ACTBL2 | LOW QUALITY PROTEIN: beta-actin-like protein 2; Belongs to the actin family. (373 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | MYL12B | Myosin regulatory light chain 12B. (172 aa) |
| | COX1 | Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (516 aa) |
| | AGTR1 | Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
