24 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TJP1	Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1914 aa)
	DGKE	Diacylglycerol kinase. (578 aa)
	ICAM1	Intercellular adhesion molecule 1. (536 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
	FAM124B	Protein FAM124B. (462 aa)
	ATF7	Cyclic AMP-dependent transcription factor ATF-7 isoform X1. (483 aa)
	SKIL	Ski-like protein isoform X1. (684 aa)
	ARNTL2	Aryl hydrocarbon receptor nuclear translocator-like protein 2 isoform X1. (607 aa)
	PDSS1	Decaprenyl-diphosphate synthase subunit 1 isoform X1; Belongs to the FPP/GGPP synthase family. (413 aa)
	VWF	Von Willebrand factor. (2806 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	VCAM1	Vascular cell adhesion protein 1. (739 aa)
	RXFP1	Relaxin receptor 1 isoform X1. (785 aa)
	LOC111182630	Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
	PECAM1	Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
	ECSCR	Endothelial cell-specific chemotaxis regulator isoform X5. (203 aa)
	CHST1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (411 aa)
	P4HA3	Prolyl 4-hydroxylase subunit alpha-3. (544 aa)
	THBD	Thrombomodulin. (584 aa)
	GOLGA3	Golgin subfamily A member 3 isoform X1. (1497 aa)
	AFM	Afamin isoform X1. (616 aa)
	HHIP	Hedgehog-interacting protein isoform X1. (700 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN5	ICAM1	A0A2Y9LBV6	A0A2Y9LUE6	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Intercellular adhesion molecule 1.	0.514
CLDN5	LOC111182630	A0A2Y9LBV6	A0A2Y9PGA8	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Platelet endothelial cell adhesion molecule-like isoform X2.	0.539
CLDN5	PECAM1	A0A2Y9LBV6	A0A2Y9PNJ4	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Platelet endothelial cell adhesion molecule isoform X1.	0.539
CLDN5	TJP1	A0A2Y9LBV6	A0A2Y9LKM7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family.	0.964
CLDN5	VCAM1	A0A2Y9LBV6	A0A2Y9P147	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Vascular cell adhesion protein 1.	0.445
CLDN5	VWF	A0A2Y9LBV6	A0A2Y9NUB3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Von Willebrand factor.	0.855
CSDE1	GOLGA3	A0A2Y9P0H2	A0A2Y9Q7H4	Cold shock domain-containing protein E1 isoform X1.	Golgin subfamily A member 3 isoform X1.	0.571
DGKE	THBD	A0A2Y9LME8	A0A2Y9Q3F5	Diacylglycerol kinase.	Thrombomodulin.	0.769
GOLGA3	CSDE1	A0A2Y9Q7H4	A0A2Y9P0H2	Golgin subfamily A member 3 isoform X1.	Cold shock domain-containing protein E1 isoform X1.	0.571
ICAM1	CLDN5	A0A2Y9LUE6	A0A2Y9LBV6	Intercellular adhesion molecule 1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.514
ICAM1	LOC111182630	A0A2Y9LUE6	A0A2Y9PGA8	Intercellular adhesion molecule 1.	Platelet endothelial cell adhesion molecule-like isoform X2.	0.620
ICAM1	PECAM1	A0A2Y9LUE6	A0A2Y9PNJ4	Intercellular adhesion molecule 1.	Platelet endothelial cell adhesion molecule isoform X1.	0.620
ICAM1	THBD	A0A2Y9LUE6	A0A2Y9Q3F5	Intercellular adhesion molecule 1.	Thrombomodulin.	0.517
ICAM1	VCAM1	A0A2Y9LUE6	A0A2Y9P147	Intercellular adhesion molecule 1.	Vascular cell adhesion protein 1.	0.795
ICAM1	VWF	A0A2Y9LUE6	A0A2Y9NUB3	Intercellular adhesion molecule 1.	Von Willebrand factor.	0.664
LOC111182630	CLDN5	A0A2Y9PGA8	A0A2Y9LBV6	Platelet endothelial cell adhesion molecule-like isoform X2.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.539
LOC111182630	ICAM1	A0A2Y9PGA8	A0A2Y9LUE6	Platelet endothelial cell adhesion molecule-like isoform X2.	Intercellular adhesion molecule 1.	0.620
LOC111182630	VCAM1	A0A2Y9PGA8	A0A2Y9P147	Platelet endothelial cell adhesion molecule-like isoform X2.	Vascular cell adhesion protein 1.	0.678
LOC111182630	VWF	A0A2Y9PGA8	A0A2Y9NUB3	Platelet endothelial cell adhesion molecule-like isoform X2.	Von Willebrand factor.	0.658
PECAM1	CLDN5	A0A2Y9PNJ4	A0A2Y9LBV6	Platelet endothelial cell adhesion molecule isoform X1.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.539