STRINGSTRING
XBP1 XBP1 TRIB2 TRIB2 CEBPE CEBPE TRIB1 TRIB1 ATF6B ATF6B ATF6 ATF6 DDIT3 DDIT3 HSPA5 HSPA5 CEBPG CEBPG ATF5 ATF5 ERN1 ERN1 ATF3 ATF3 ATF4 ATF4 CEBPB CEBPB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
TRIB2Tribbles homolog 2. (343 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
TRIB1Tribbles homolog 1. (372 aa)
ATF6BLOW QUALITY PROTEIN: cyclic AMP-dependent transcription factor ATF-6 beta. (700 aa)
ATF6Cyclic AMP-dependent transcription factor ATF-6 alpha. (654 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (655 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (149 aa)
ATF5Cyclic AMP-dependent transcription factor ATF-5. (279 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3 isoform X1. (221 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X1. (350 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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