STRINGSTRING
CRKL CRKL BCR BCR FGR FGR FYN FYN PAG1 PAG1 PIK3CG PIK3CG SH3GL3 SH3GL3 VAV1 VAV1 PIK3R2 PIK3R2 SHC1 SHC1 LYN LYN PTK2 PTK2 KHDRBS3 KHDRBS3 MATK MATK SH3GL1 SH3GL1 CBL CBL SHC3 SHC3 LOC111167689 LOC111167689 PTPRC PTPRC LOC111167795 LOC111167795 TEC TEC LOC111170545 LOC111170545 TXK TXK ELMO2 ELMO2 DOCK1 DOCK1 INPPL1 INPPL1 SHC2 SHC2 INPP5D INPP5D SOS2 SOS2 PIK3CA PIK3CA SH3GL2 SH3GL2 SOS1 SOS1 TIAM1 TIAM1 BLNK BLNK KHDRBS1 KHDRBS1 PIK3R3 PIK3R3 VAV2 VAV2 MST1R MST1R RAPGEF1 RAPGEF1 BTK BTK MET MET PLCG2 PLCG2 BCAR1 BCAR1 PIK3CB PIK3CB AXL AXL VAV3 VAV3 ELMO1 ELMO1 GP6 GP6 SPIRE2 SPIRE2 NEDD9 NEDD9 ELMO3 ELMO3 YES1 YES1 ITK ITK GRB2 GRB2 RAC1 RAC1 PLCG1 PLCG1 LAT LAT LOC111184310 LOC111184310 FER FER SRC SRC HCK HCK DOCK5 DOCK5 CRK CRK CBLB CBLB LOC111186271 LOC111186271 DOCK2 DOCK2 GAB2 GAB2 LOC111186270 LOC111186270 PTK2B PTK2B LCP2 LCP2 PIK3R1 PIK3R1 PIK3R5 PIK3R5 PIK3R6 PIK3R6 PTK6 PTK6 GAB1 GAB1 PTPN11 PTPN11 LOC111187198 LOC111187198 PIK3CD PIK3CD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRKLCrk-like protein. (303 aa)
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
FGRTyrosine-protein kinase. (526 aa)
FYNTyrosine-protein kinase. (537 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 isoform X2. (436 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
SH3GL3endophilin-A3 isoform X1. (347 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
LYNTyrosine-protein kinase. (518 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
KHDRBS3KH domain-containing, RNA-binding, signal transduction-associated protein 3 isoform X1. (346 aa)
MATKTyrosine-protein kinase. (706 aa)
SH3GL1endophilin-A2 isoform X1. (403 aa)
CBLE3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
SHC3SHC-transforming protein 3. (588 aa)
LOC111167689GRB2-related adapter protein. (217 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
LOC111167795Rho-related GTP-binding protein RhoG-like isoform X1. (230 aa)
TECTyrosine-protein kinase. (658 aa)
LOC111170545Rho-related GTP-binding protein RhoG. (191 aa)
TXKTyrosine-protein kinase. (550 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (720 aa)
DOCK1Dedicator of cytokinesis protein 1 isoform X1; Belongs to the DOCK family. (1886 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa)
SHC2SHC-transforming protein 2 isoform X1. (588 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
SOS2Son of sevenless homolog 2 isoform X1. (1332 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SH3GL2endophilin-A1. (352 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1 isoform X3. (1606 aa)
BLNKB-cell linker protein isoform X1. (528 aa)
KHDRBS1KH domain-containing, RNA-binding, signal transduction-associated protein 1. (443 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
MST1RMacrophage-stimulating protein receptor isoform X1. (1406 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1259 aa)
BTKTyrosine-protein kinase. (687 aa)
METHepatocyte growth factor receptor isoform X1. (1382 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X4. (867 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
VAV3Guanine nucleotide exchange factor VAV3. (954 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (727 aa)
GP6Platelet glycoprotein VI isoform X1. (464 aa)
SPIRE2Protein spire homolog 2 isoform X1. (713 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (782 aa)
YES1Tyrosine-protein kinase. (541 aa)
ITKTyrosine-protein kinase. (620 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (192 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (270 aa)
LOC111184310Tyrosine-protein kinase. (369 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
SRCTyrosine-protein kinase. (562 aa)
HCKTyrosine-protein kinase. (506 aa)
DOCK5Dedicator of cytokinesis protein 5 isoform X1; Belongs to the DOCK family. (1869 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
CBLBE3 ubiquitin-protein ligase CBL-B. (983 aa)
LOC111186271GRB2-related adapter protein 2-like isoform X1. (105 aa)
DOCK2Dedicator of cytokinesis protein 2 isoform X1; Belongs to the DOCK family. (1828 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
LOC111186270GRB2-related adapter protein 2 isoform X1. (337 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
LCP2Lymphocyte cytosolic protein 2 isoform X1. (534 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (871 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa)
PTK6Non-specific protein-tyrosine kinase. (354 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (757 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.