41 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BCR	Breakpoint cluster region protein isoform X1. (1275 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PIK3CG	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
	VAV1	Proto-oncogene vav isoform X1. (845 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	SHC3	SHC-transforming protein 3. (588 aa)
	TEC	Tyrosine-protein kinase. (658 aa)
	TXK	Tyrosine-protein kinase. (550 aa)
	INPPL1	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa)
	SHC2	SHC-transforming protein 2 isoform X1. (588 aa)
	INPP5D	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
	SOS2	Son of sevenless homolog 2 isoform X1. (1332 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	TIAM1	T-lymphoma invasion and metastasis-inducing protein 1 isoform X3. (1606 aa)
	BLNK	B-cell linker protein isoform X1. (528 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
	VAV2	Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
	BTK	Tyrosine-protein kinase. (687 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	AXL	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (954 aa)
	GP6	Platelet glycoprotein VI isoform X1. (464 aa)
	ITK	Tyrosine-protein kinase. (620 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	RAC1	Ras-related C3 botulinum toxin substrate 1. (192 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
	LAT	Linker for activation of T-cells family member 1 isoform X1. (270 aa)
	GAB2	GRB2-associated-binding protein 2 isoform X1. (678 aa)
	LOC111186270	GRB2-related adapter protein 2 isoform X1. (337 aa)
	LCP2	Lymphocyte cytosolic protein 2 isoform X1. (534 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	PIK3R5	Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (871 aa)
	PIK3R6	Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa)
	GAB1	GRB2-associated-binding protein 1 isoform X1. (757 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	LOC111187198	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXL	GAB1	A0A2Y9P2K3	A0A2Y9QCZ2	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	GRB2-associated-binding protein 1 isoform X1.	0.929
AXL	GRB2	A0A2Y9P2K3	A0A2Y9PJ90	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	Growth factor receptor-bound protein 2.	0.573
AXL	PIK3CA	A0A2Y9P2K3	A0A2Y9MZW2	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.647
AXL	PIK3CB	A0A2Y9P2K3	A0A2Y9NZC3	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.419
AXL	PIK3R1	A0A2Y9P2K3	A0A2Y9Q8T5	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.593
AXL	PIK3R2	A0A2Y9P2K3	A0A2Y9LXY5	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.437
AXL	PLCG1	A0A2Y9P2K3	A0A2Y9PMG8	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.936
AXL	PLCG2	A0A2Y9P2K3	A0A2Y9NXP3	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.942
AXL	SHC1	A0A2Y9P2K3	A0A2Y9LZK9	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	SHC-transforming protein 1 isoform X1.	0.932
AXL	SHC2	A0A2Y9P2K3	A0A2Y9MVZ5	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	SHC-transforming protein 2 isoform X1.	0.920
AXL	SHC3	A0A2Y9P2K3	A0A2Y9M5N9	LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO.	SHC-transforming protein 3.	0.932
BCR	GRB2	A0A2Y9LBZ9	A0A2Y9PJ90	Breakpoint cluster region protein isoform X1.	Growth factor receptor-bound protein 2.	0.973
BCR	PIK3CG	A0A2Y9LBZ9	A0A2Y9LSJ4	Breakpoint cluster region protein isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family.	0.435
BCR	RAC1	A0A2Y9LBZ9	A0A2Y9PL77	Breakpoint cluster region protein isoform X1.	Ras-related C3 botulinum toxin substrate 1.	0.429
BCR	SHC1	A0A2Y9LBZ9	A0A2Y9LZK9	Breakpoint cluster region protein isoform X1.	SHC-transforming protein 1 isoform X1.	0.901
BCR	SHC2	A0A2Y9LBZ9	A0A2Y9MVZ5	Breakpoint cluster region protein isoform X1.	SHC-transforming protein 2 isoform X1.	0.900
BCR	SHC3	A0A2Y9LBZ9	A0A2Y9M5N9	Breakpoint cluster region protein isoform X1.	SHC-transforming protein 3.	0.901
BLNK	BTK	A0A2Y9N6S7	A0A2Y9NR66	B-cell linker protein isoform X1.	Tyrosine-protein kinase.	0.984
BLNK	FYN	A0A2Y9N6S7	A0A2Y9LLH3	B-cell linker protein isoform X1.	Tyrosine-protein kinase.	0.408
BLNK	GRB2	A0A2Y9N6S7	A0A2Y9PJ90	B-cell linker protein isoform X1.	Growth factor receptor-bound protein 2.	0.997