STRINGSTRING
LOC111163114 LOC111163114 GP2 GP2 SELPLG SELPLG CD40LG CD40LG ICAM3 ICAM3 CD209 CD209 CD70 CD70 ICAM1 ICAM1 CD3D CD3D CD3G CD3G CD3E CD3E CD8A CD8A CD8B CD8B SELP SELP SELE SELE EOMES EOMES CD247 CD247 SELL SELL CD40 CD40 CD80 CD80 LOC111170420 LOC111170420 PXDN PXDN CD86 CD86 ICOS ICOS LOC111170413 LOC111170413 CD28 CD28 PDCD1 PDCD1 LOC111172230 LOC111172230 CTLA4 CTLA4 LOC111171171 LOC111171171 CD274 CD274 HYAL3 HYAL3 PDCD1LG2 PDCD1LG2 LOC111176758 LOC111176758 CD27 CD27 LOC111176714 LOC111176714 KLRD1 KLRD1 LCK LCK CSK CSK LAG3 LAG3 GLG1 GLG1 CD58 CD58 CD2 CD2 CD83 CD83 PTPN22 PTPN22 LOC111182106 LOC111182106 CD177 CD177 SPN SPN ITGAM ITGAM ICAM2 ICAM2 LOC111182630 LOC111182630 NCR1 NCR1 SIGLEC10 SIGLEC10 NKG7 NKG7 ITGAL ITGAL PRF1 PRF1 PECAM1 PECAM1 CD7 CD7 CTSW CTSW CD34 CD34 CD6 CD6 CD5 CD5 SIGLEC1 SIGLEC1 LOC111186264 LOC111186264 ITGAE ITGAE GZMK GZMK ALCAM ALCAM LGALS9 LGALS9 LOC111187417 LOC111187417 ANXA5 ANXA5 ITGB2 ITGB2 CD4 CD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111163114Granzyme A; Belongs to the peptidase S1 family. (258 aa)
GP2Pancreatic secretory granule membrane major glycoprotein GP2. (530 aa)
SELPLGP-selectin glycoprotein ligand 1. (450 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
ICAM3Intercellular adhesion molecule 3 isoform X1. (545 aa)
CD209CD209 antigen. (279 aa)
CD70CD70 antigen isoform X1; Belongs to the tumor necrosis factor family. (298 aa)
ICAM1Intercellular adhesion molecule 1. (536 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (171 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (178 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (197 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain isoform X1. (239 aa)
CD8BT-cell surface glycoprotein CD8 beta chain. (210 aa)
SELPP-selectin isoform X1. (768 aa)
SELEE-selectin. (531 aa)
EOMESEomesodermin homolog isoform X1. (711 aa)
CD247T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (372 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa)
CD80T-lymphocyte activation antigen CD80 isoform X1. (295 aa)
LOC111170420Low affinity immunoglobulin gamma Fc region receptor II-like isoform X1. (144 aa)
PXDNPeroxidasin homolog isoform X3. (1478 aa)
CD86T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
ICOSInducible T-cell costimulator isoform X1. (227 aa)
LOC111170413Low affinity immunoglobulin gamma Fc region receptor III-like isoform X1. (278 aa)
CD28T-cell-specific surface glycoprotein CD28. (265 aa)
PDCD1Programmed cell death protein 1 isoform X1. (288 aa)
LOC111172230Deleted in malignant brain tumors 1 protein isoform X1. (684 aa)
CTLA4Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
LOC111171171Integrin alpha-M-like. (296 aa)
CD274Programmed cell death 1 ligand 1 isoform X2. (312 aa)
HYAL3Hyaluronidase. (415 aa)
PDCD1LG2Programmed cell death 1 ligand 2 isoform X1. (337 aa)
LOC111176758NKG2-A/NKG2-B type II integral membrane protein-like isoform X1. (256 aa)
CD27CD27 antigen isoform X1. (251 aa)
LOC111176714Scavenger receptor cysteine-rich type 1 protein M130 isoform X1. (1115 aa)
KLRD1Natural killer cells antigen CD94 isoform X1. (240 aa)
LCKTyrosine-protein kinase. (509 aa)
CSKTyrosine-protein kinase. (528 aa)
LAG3Lymphocyte activation gene 3 protein. (493 aa)
GLG1Golgi apparatus protein 1. (1181 aa)
CD58Lymphocyte function-associated antigen 3 isoform X1. (242 aa)
CD2T-cell surface antigen CD2 isoform X1. (340 aa)
CD83CD83 antigen isoform X1. (195 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa)
LOC111182106Integrin alpha-X-like isoform X1; Belongs to the integrin alpha chain family. (1210 aa)
CD177CD177 antigen isoform X1. (443 aa)
SPNLeukosialin. (411 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (872 aa)
ICAM2Intercellular adhesion molecule 2 isoform X1. (292 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
NCR1Natural cytotoxicity triggering receptor 1 isoform X1. (330 aa)
SIGLEC10Sialic acid-binding Ig-like lectin 10 isoform X1. (706 aa)
NKG7Protein NKG7. (165 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa)
PRF1Perforin-1. (555 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
CD7T-cell antigen CD7. (208 aa)
CTSWCathepsin W isoform X1; Belongs to the peptidase C1 family. (386 aa)
CD34Hematopoietic progenitor cell antigen CD34 isoform X1. (384 aa)
CD6T-cell differentiation antigen CD6 isoform X1. (675 aa)
CD5T-cell surface glycoprotein CD5 isoform X1. (500 aa)
SIGLEC1Sialoadhesin isoform X1. (1726 aa)
LOC111186264ICOS ligand-like isoform X1. (580 aa)
ITGAEIntegrin alpha-E; Belongs to the integrin alpha chain family. (1173 aa)
GZMKGranzyme K; Belongs to the peptidase S1 family. (264 aa)
ALCAMCD166 antigen isoform X1. (583 aa)
LGALS9Galectin. (356 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
ANXA5Annexin. (370 aa)
ITGB2Integrin beta. (769 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (455 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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