75 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UCP2	Mitochondrial uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
	CIDEA	Cell death activator CIDE-A. (219 aa)
	GPIHBP1	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1. (199 aa)
	ABCG1	ATP-binding cassette sub-family G member 1 isoform X1. (693 aa)
	FABP5	Fatty acid-binding protein, epidermal isoform X1. (140 aa)
	FABP1	Fatty acid-binding protein, liver. (127 aa)
	LOC111163515	Uncharacterized protein LOC111163515. (1806 aa)
	PLIN5	Perilipin; Belongs to the perilipin family. (454 aa)
	PLIN4	Perilipin; Belongs to the perilipin family. (473 aa)
	ANGPTL8	Angiopoietin-like protein 8 isoform X1. (242 aa)
	LOC111164929	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	ABHD5	1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform X1. (389 aa)
	APOC3	Apolipoprotein C-III. (99 aa)
	APCS	LOW QUALITY PROTEIN: serum amyloid P-component. (139 aa)
	APOA1	Apolipoprotein A-I. (265 aa)
	APOA2	Apolipoprotein A-II. (103 aa)
	RETN	Resistin isoform X2. (158 aa)
	ANGPTL4	Angiopoietin-related protein 4. (412 aa)
	LOC111167597	Transmembrane protein 26. (368 aa)
	APOA4	Apolipoprotein A-IV isoform X1. (380 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (478 aa)
	FABP7	Fatty acid-binding protein, brain; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	SREBF1	Sterol regulatory element-binding protein 1 isoform X1. (1213 aa)
	APOA5	Apolipoprotein A-V isoform X1. (390 aa)
	PLIN1	Perilipin; Belongs to the perilipin family. (517 aa)
	CRP	Pentaxin. (222 aa)
	PNPLA2	Patatin-like phospholipase domain-containing protein 2 isoform X1. (489 aa)
	MBTPS2	Membrane-bound transcription factor site-2 protease isoform X1. (578 aa)
	APOM	Apolipoprotein M isoform X1. (188 aa)
	CIDEC	Cell death activator CIDE-3. (248 aa)
	APOD	Apolipoprotein D. (213 aa)
	PPARGC1A	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa)
	PLTP	Phospholipid transfer protein. (496 aa)
	ABCG5	LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5. (652 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (455 aa)
	SERPINA6	Corticosteroid-binding globulin; Belongs to the serpin family. (404 aa)
	APOB	Apolipoprotein B-100. (4566 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9 isoform X1. (692 aa)
	NPC2	Epididymal secretory protein E1. (149 aa)
	BCHE	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (643 aa)
	ANGPTL2	Angiopoietin-related protein 2. (493 aa)
	SCAP	Sterol regulatory element-binding protein cleavage-activating protein isoform X1. (1280 aa)
	FABP3	Fatty acid-binding protein, heart isoform X1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (162 aa)
	ANGPTL3	Angiopoietin-related protein 3. (460 aa)
	APOC1	LOW QUALITY PROTEIN: apolipoprotein C-I. (87 aa)
	MTTP	Microsomal triglyceride transfer protein large subunit. (894 aa)
	LCAT	Phosphatidylcholine-sterol acyltransferase isoform X1. (440 aa)
	LOC111176941	LOW QUALITY PROTEIN: epididymal-specific lipocalin-5-like; Belongs to the calycin superfamily. Lipocalin family. (229 aa)
	NRF1	Nuclear respiratory factor 1 isoform X1. (517 aa)
	APOE	Apolipoprotein E. (316 aa)
	PON2	Serum paraoxonase/arylesterase 2 isoform X1. (354 aa)
	MBTPS1	Membrane-bound transcription factor site-1 protease isoform X1. (1054 aa)
	PON1	LOW QUALITY PROTEIN: serum paraoxonase/arylesterase 1. (360 aa)
	APOC2	Apolipoprotein C-II. (101 aa)
	NPC1	Niemann-Pick C1 protein isoform X1. (1277 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
	PON3	Serum paraoxonase/lactonase 3 isoform X1. (354 aa)
	FITM2	Fat storage-inducing transmembrane protein 2. (271 aa)
	ESRRA	Steroid hormone receptor ERR1. (422 aa)
	GM2A	Ganglioside GM2 activator. (196 aa)
	UCP3	Mitochondrial uncoupling protein 3 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
	FAM149B1	Protein FAM149B1 isoform X1. (585 aa)
	INSIG2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (229 aa)
	LMF1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (595 aa)
	HPGD	15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
	NPC1L1	Niemann-Pick C1-like protein 1 isoform X1. (1331 aa)
	SHBG	Sex hormone-binding globulin isoform X2. (377 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha. (468 aa)
	FABP6	Gastrotropin. (128 aa)
	SCARB1	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (511 aa)
	FABP2	Fatty acid-binding protein, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	SREBF2	Sterol regulatory element-binding protein 2 isoform X1. (1135 aa)
	AFM	Afamin isoform X1. (616 aa)
	CUNH12orf49	UPF0454 protein C12orf49 homolog isoform X1. (340 aa)
	ABCA1	ATP-binding cassette sub-family A member 1 isoform X1. (2273 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	ABCG1	A0A2Y9QL54	A0A2Y9LNX3	ATP-binding cassette sub-family A member 1 isoform X1.	ATP-binding cassette sub-family G member 1 isoform X1.	0.447
ABCA1	APOA1	A0A2Y9QL54	A0A2Y9LZH5	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein A-I.	0.936
ABCA1	APOA2	A0A2Y9QL54	A0A2Y9LZM5	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein A-II.	0.519
ABCA1	APOB	A0A2Y9QL54	A0A2Y9NAV4	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein B-100.	0.606
ABCA1	APOC3	A0A2Y9QL54	A0A2Y9LYW0	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein C-III.	0.473
ABCA1	APOD	A0A2Y9QL54	A0A2Y9MS43	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein D.	0.433
ABCA1	APOE	A0A2Y9QL54	A0A2Y9P221	ATP-binding cassette sub-family A member 1 isoform X1.	Apolipoprotein E.	0.757
ABCA1	LCAT	A0A2Y9QL54	A0A2Y9NVT8	ATP-binding cassette sub-family A member 1 isoform X1.	Phosphatidylcholine-sterol acyltransferase isoform X1.	0.610
ABCA1	LPL	A0A2Y9QL54	A0A2Y9M8T8	ATP-binding cassette sub-family A member 1 isoform X1.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.434
ABCA1	MTTP	A0A2Y9QL54	A0A2Y9NVR8	ATP-binding cassette sub-family A member 1 isoform X1.	Microsomal triglyceride transfer protein large subunit.	0.442
ABCA1	NPC1	A0A2Y9QL54	A0A2Y9PBA7	ATP-binding cassette sub-family A member 1 isoform X1.	Niemann-Pick C1 protein isoform X1.	0.524
ABCA1	NPC1L1	A0A2Y9QL54	A0A2Y9PZQ3	ATP-binding cassette sub-family A member 1 isoform X1.	Niemann-Pick C1-like protein 1 isoform X1.	0.528
ABCA1	NPC2	A0A2Y9QL54	A0A2Y9NBL8	ATP-binding cassette sub-family A member 1 isoform X1.	Epididymal secretory protein E1.	0.434
ABCA1	PLIN2	A0A2Y9QL54	A0A2Y9N5I1	ATP-binding cassette sub-family A member 1 isoform X1.	Perilipin; Belongs to the perilipin family.	0.443
ABCA1	PLTP	A0A2Y9QL54	A0A2Y9MU55	ATP-binding cassette sub-family A member 1 isoform X1.	Phospholipid transfer protein.	0.514
ABCA1	PPARA	A0A2Y9QL54	A0A2Y9Q177	ATP-binding cassette sub-family A member 1 isoform X1.	Peroxisome proliferator-activated receptor alpha.	0.450
ABCA1	SCARB1	A0A2Y9QL54	A0A2Y9Q8K4	ATP-binding cassette sub-family A member 1 isoform X1.	Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family.	0.711
ABCA1	SREBF1	A0A2Y9QL54	A0A2Y9MBW8	ATP-binding cassette sub-family A member 1 isoform X1.	Sterol regulatory element-binding protein 1 isoform X1.	0.504
ABCA1	SREBF2	A0A2Y9QL54	A0A2Y9QB94	ATP-binding cassette sub-family A member 1 isoform X1.	Sterol regulatory element-binding protein 2 isoform X1.	0.516
ABCG1	ABCA1	A0A2Y9LNX3	A0A2Y9QL54	ATP-binding cassette sub-family G member 1 isoform X1.	ATP-binding cassette sub-family A member 1 isoform X1.	0.447