STRINGSTRING
F3 F3 SERPIND1 SERPIND1 F9 F9 F5 F5 PLG PLG SERPINC1 SERPINC1 F12 F12 LOC111173428 LOC111173428 FETUB FETUB LOC111171268 LOC111171268 TFPI TFPI ITIH4 ITIH4 AHSG AHSG SERPINA5 SERPINA5 SERPINA1 SERPINA1 F10 F10 LOC111176120 LOC111176120 LOC111177292 LOC111177292 F13B F13B SERPINA10 SERPINA10 AMBP AMBP F7 F7 PROZ PROZ LOC111176737 LOC111176737 PROS1 PROS1 SERPINB5 SERPINB5 F13A1 F13A1 TFPI2 TFPI2 APOH APOH PROCR PROCR PROC PROC F2 F2 SERPINF2 SERPINF2 THBD THBD FGB FGB FGA FGA FGG FGG GC GC ALB ALB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
SERPIND1Heparin cofactor 2 isoform X2; Belongs to the serpin family. (496 aa)
F9Coagulation factor IX. (462 aa)
F5Coagulation factor V isoform X1; Belongs to the multicopper oxidase family. (2169 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
SERPINC1antithrombin-III isoform X1; Belongs to the serpin family. (501 aa)
F12LOW QUALITY PROTEIN: coagulation factor XII. (650 aa)
LOC111173428Coagulation factor XI; Belongs to the peptidase S1 family. (633 aa)
FETUBfetuin-B. (384 aa)
LOC111171268Coagulation factor VIII-like. (177 aa)
TFPITissue factor pathway inhibitor isoform X1. (307 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain H4 isoform X1. (999 aa)
AHSGalpha-2-HS-glycoprotein. (360 aa)
SERPINA5Plasma serine protease inhibitor isoform X1; Belongs to the serpin family. (408 aa)
SERPINA1Alpha-1-antitrypsin; Belongs to the serpin family. (421 aa)
F10Coagulation factor X isoform X1. (480 aa)
LOC111176120LOW QUALITY PROTEIN: serpin A3-8-like; Belongs to the serpin family. (423 aa)
LOC111177292Alpha-1-acid glycoprotein-like isoform X1. (218 aa)
F13BCoagulation factor XIII B chain. (660 aa)
SERPINA10Protein Z-dependent protease inhibitor; Belongs to the serpin family. (446 aa)
AMBPProtein AMBP. (352 aa)
F7Coagulation factor VII isoform X1. (447 aa)
PROZVitamin K-dependent protein Z; Belongs to the peptidase S1 family. (709 aa)
LOC111176737Alpha-2-macroglobulin isoform X1. (1479 aa)
PROS1Vitamin K-dependent protein S. (675 aa)
SERPINB5Serpin B5; Belongs to the serpin family. (375 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
TFPI2Tissue factor pathway inhibitor. (300 aa)
APOHBeta-2-glycoprotein 1 isoform X1. (345 aa)
PROCREndothelial protein C receptor. (242 aa)
PROCVitamin K-dependent protein C. (480 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (558 aa)
THBDThrombomodulin. (584 aa)
FGBFibrinogen beta chain isoform X1. (495 aa)
FGAFibrinogen alpha chain. (852 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
GCVitamin D-binding protein isoform X1. (519 aa)
ALBSerum albumin. (607 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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