11 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	F3	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
	F9	Coagulation factor IX. (462 aa)
	F5	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family. (2169 aa)
	LOC111173428	Coagulation factor XI; Belongs to the peptidase S1 family. (633 aa)
	LOC111171268	Coagulation factor VIII-like. (177 aa)
	TFPI	Tissue factor pathway inhibitor isoform X1. (307 aa)
	F7	Coagulation factor VII isoform X1. (447 aa)
	PROS1	Vitamin K-dependent protein S. (675 aa)
	TFPI2	Tissue factor pathway inhibitor. (300 aa)
	PROCR	Endothelial protein C receptor. (242 aa)
	THBD	Thrombomodulin. (584 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F3	F7	A0A2Y9LHF9	A0A2Y9NSN2	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Coagulation factor VII isoform X1.	0.999
F3	F9	A0A2Y9LHF9	A0A2Y9LSD8	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Coagulation factor IX.	0.794
F3	LOC111173428	A0A2Y9LHF9	A0A2Y9MXX5	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Coagulation factor XI; Belongs to the peptidase S1 family.	0.631
F3	PROCR	A0A2Y9LHF9	A0A2Y9PRU2	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Endothelial protein C receptor.	0.509
F3	TFPI	A0A2Y9LHF9	A0A2Y9N0V1	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Tissue factor pathway inhibitor isoform X1.	0.814
F3	TFPI2	A0A2Y9LHF9	A0A2Y9PEZ8	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Tissue factor pathway inhibitor.	0.706
F3	THBD	A0A2Y9LHF9	A0A2Y9Q3F5	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	Thrombomodulin.	0.761
F5	F7	A0A2Y9M1F9	A0A2Y9NSN2	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.	Coagulation factor VII isoform X1.	0.652
F5	F9	A0A2Y9M1F9	A0A2Y9LSD8	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.	Coagulation factor IX.	0.664
F5	LOC111171268	A0A2Y9M1F9	A0A2Y9MZQ8	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.	Coagulation factor VIII-like.	0.607
F5	LOC111173428	A0A2Y9M1F9	A0A2Y9MXX5	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.	Coagulation factor XI; Belongs to the peptidase S1 family.	0.409
F5	PROS1	A0A2Y9M1F9	A0A2Y9NVN3	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.	Vitamin K-dependent protein S.	0.994
F5	THBD	A0A2Y9M1F9	A0A2Y9Q3F5	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.	Thrombomodulin.	0.568
F7	F3	A0A2Y9NSN2	A0A2Y9LHF9	Coagulation factor VII isoform X1.	Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.	0.999
F7	F5	A0A2Y9NSN2	A0A2Y9M1F9	Coagulation factor VII isoform X1.	Coagulation factor V isoform X1; Belongs to the multicopper oxidase family.	0.652
F7	F9	A0A2Y9NSN2	A0A2Y9LSD8	Coagulation factor VII isoform X1.	Coagulation factor IX.	0.741
F7	LOC111171268	A0A2Y9NSN2	A0A2Y9MZQ8	Coagulation factor VII isoform X1.	Coagulation factor VIII-like.	0.640
F7	PROCR	A0A2Y9NSN2	A0A2Y9PRU2	Coagulation factor VII isoform X1.	Endothelial protein C receptor.	0.510
F7	TFPI	A0A2Y9NSN2	A0A2Y9N0V1	Coagulation factor VII isoform X1.	Tissue factor pathway inhibitor isoform X1.	0.968
F7	TFPI2	A0A2Y9NSN2	A0A2Y9PEZ8	Coagulation factor VII isoform X1.	Tissue factor pathway inhibitor.	0.547