STRINGSTRING
NF2 NF2 AMOT AMOT LATS1 LATS1 TEAD1 TEAD1 MOB1A MOB1A AMOTL1 AMOTL1 YAP1 YAP1 SAV1 SAV1 LATS2 LATS2 MPDZ MPDZ TEAD3 TEAD3 WWTR1 WWTR1 AMOTL2 AMOTL2 TEAD2 TEAD2 STK3 STK3 MOB1B MOB1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NF2Merlin isoform X3. (619 aa)
AMOTAngiomotin isoform X1. (1081 aa)
LATS1Serine/threonine-protein kinase LATS1. (1128 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X3. (523 aa)
MOB1AMOB kinase activator 1A. (216 aa)
AMOTL1Angiomotin-like protein 1 isoform X1. (956 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (511 aa)
SAV1Protein salvador homolog 1. (385 aa)
LATS2Serine/threonine-protein kinase LATS2. (1043 aa)
MPDZMultiple PDZ domain protein isoform X1. (2071 aa)
TEAD3Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (460 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
AMOTL2Angiomotin-like protein 2 isoform X1. (775 aa)
TEAD2Transcriptional enhancer factor TEF-4 isoform X3. (239 aa)
STK3Serine/threonine-protein kinase 3. (491 aa)
MOB1BMOB kinase activator 1B isoform X1. (216 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (16%) [HD]