STRINGSTRING
PTPN3 PTPN3 SAMSN1 SAMSN1 VAV2 VAV2 PIK3R3 PIK3R3 IRS1 IRS1 SYK SYK SHE SHE SH2D3A SH2D3A LOC111167689 LOC111167689 SHC3 SHC3 ABL2 ABL2 SHC1 SHC1 PTPN6 PTPN6 LCK LCK SH2D3C SH2D3C ABL1 ABL1 PLCG2 PLCG2 CRKL CRKL LDLRAP1 LDLRAP1 FGR FGR MAPK1 MAPK1 BCAR3 BCAR3 VAV1 VAV1 PTPN5 PTPN5 YES1 YES1 MAPK3 MAPK3 SHF SHF SOCS3 SOCS3 GRB2 GRB2 LOC111184310 LOC111184310 RASA1 RASA1 HCK HCK CRK CRK SH3BP2 SH3BP2 SHD SHD PIK3R2 PIK3R2 CBLB CBLB LOC111186271 LOC111186271 LOC111186270 LOC111186270 LOC111187417 LOC111187417 PIK3R1 PIK3R1 NCK2 NCK2 PTPN11 PTPN11 LOC111187198 LOC111187198 SHB SHB CBL CBL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (949 aa)
SAMSN1SAM domain-containing protein SAMSN-1. (373 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
SYKTyrosine-protein kinase. (626 aa)
SHESH2 domain-containing adapter protein E. (499 aa)
SH2D3ASH2 domain-containing protein 3A isoform X1. (601 aa)
LOC111167689GRB2-related adapter protein. (217 aa)
SHC3SHC-transforming protein 3. (588 aa)
ABL2Tyrosine-protein kinase. (1174 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
LCKTyrosine-protein kinase. (509 aa)
SH2D3CSH2 domain-containing protein 3C isoform X1. (861 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
CRKLCrk-like protein. (303 aa)
LDLRAP1LOW QUALITY PROTEIN: low density lipoprotein receptor adapter protein 1. (309 aa)
FGRTyrosine-protein kinase. (526 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3 isoform X1. (832 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
PTPN5Tyrosine-protein phosphatase non-receptor type 5. (539 aa)
YES1Tyrosine-protein kinase. (541 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
SHFLOW QUALITY PROTEIN: SH2 domain-containing adapter protein F. (489 aa)
SOCS3Suppressor of cytokine signaling 3. (237 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LOC111184310Tyrosine-protein kinase. (369 aa)
RASA1Ras GTPase-activating protein 1 isoform X1. (1040 aa)
HCKTyrosine-protein kinase. (506 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
SH3BP2SH3 domain-binding protein 2 isoform X1. (617 aa)
SHDSH2 domain-containing adapter protein D. (340 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
CBLBE3 ubiquitin-protein ligase CBL-B. (983 aa)
LOC111186271GRB2-related adapter protein 2-like isoform X1. (105 aa)
LOC111186270GRB2-related adapter protein 2 isoform X1. (337 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
NCK2Cytoplasmic protein. (376 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
SHBSH2 domain-containing adapter protein B. (507 aa)
CBLE3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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