STRINGSTRING
PTPN6 PTPN6 MYD88 MYD88 CTSH CTSH EMP2 EMP2 LYST LYST LOC111164234 LOC111164234 LOC111166483 LOC111166483 NLRP6 NLRP6 SH2D1A SH2D1A LOC111166880 LOC111166880 AZU1 AZU1 ELANE ELANE VAMP7 VAMP7 GZMM GZMM TUSC2 TUSC2 RNF19B RNF19B KIF5B KIF5B LOC111178659 LOC111178659 LAG3 LAG3 CEBPG CEBPG CD2 CD2 NKG7 NKG7 PRF1 PRF1 CORO1A CORO1A PPP3CB PPP3CB SCNN1B SCNN1B UNC13D UNC13D CTSC CTSC F2 F2 PLEKHM2 PLEKHM2 IL7R IL7R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
CTSHPro-cathepsin H; Belongs to the peptidase C1 family. (335 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
LYSTLysosomal-trafficking regulator isoform X1. (3861 aa)
LOC111164234Granzyme B-like isoform X1; Belongs to the peptidase S1 family. (248 aa)
LOC111166483Signal transducer and activator of transcription. (787 aa)
NLRP6LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 6. (876 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
LOC111166880LOW QUALITY PROTEIN: NKG2D ligand 4-like. (234 aa)
AZU1Azurocidin. (252 aa)
ELANENeutrophil elastase; Belongs to the peptidase S1 family. (308 aa)
VAMP7Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
GZMMGranzyme M; Belongs to the peptidase S1 family. (257 aa)
TUSC2Tumor suppressor candidate 2. (110 aa)
RNF19BRBR-type E3 ubiquitin transferase. (732 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
LOC111178659Antigen peptide transporter 2-like isoform X4. (758 aa)
LAG3Lymphocyte activation gene 3 protein. (493 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (149 aa)
CD2T-cell surface antigen CD2 isoform X1. (340 aa)
NKG7Protein NKG7. (165 aa)
PRF1Perforin-1. (555 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
UNC13DProtein unc-13 homolog D isoform X1. (1121 aa)
CTSCDipeptidyl peptidase 1 isoform X1; Belongs to the peptidase C1 family. (463 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
PLEKHM2Pleckstrin homology domain-containing family M member 2 isoform X1. (1024 aa)
IL7RInterleukin-7 receptor subunit alpha isoform X1. (459 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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