19 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYOC	Myocilin. (476 aa)
	LOXL3	Lysyl oxidase homolog 3 isoform X1. (772 aa)
	CTSK	Cathepsin K isoform X1; Belongs to the peptidase C1 family. (358 aa)
	CTSS	Cathepsin S; Belongs to the peptidase C1 family. (340 aa)
	FSTL3	Follistatin-related protein 3. (262 aa)
	CUNH6orf15	Uncharacterized protein C6orf15 homolog. (298 aa)
	MFAP2	Microfibrillar-associated protein 2 isoform X1. (183 aa)
	FBLN1	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
	CCDC80	Coiled-coil domain-containing protein 80. (951 aa)
	HSD17B12	Very-long-chain 3-oxoacyl-CoA reductase isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (348 aa)
	IGFBP3	Insulin-like growth factor-binding protein 3. (293 aa)
	SDC4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
	THBS1	Thrombospondin-1. (1170 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (789 aa)
	EPHA1	Ephrin type-A receptor 1 isoform X1. (981 aa)
	IGFBP6	Insulin-like growth factor-binding protein 6. (236 aa)
	LRRC15	Leucine-rich repeat-containing protein 15. (571 aa)
	TNFAIP6	Tumor necrosis factor-inducible gene 6 protein isoform X1. (284 aa)
	ITGAV	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSK	ITGB3	A0A2Y9MDR7	A0A2Y9PCY7	Cathepsin K isoform X1; Belongs to the peptidase C1 family.	Integrin beta; Belongs to the integrin beta chain family.	0.552
CTSS	ITGB3	A0A2Y9MDS1	A0A2Y9PCY7	Cathepsin S; Belongs to the peptidase C1 family.	Integrin beta; Belongs to the integrin beta chain family.	0.407
FBLN1	MFAP2	A0A2Y9QAW1	A0A2Y9QGA8	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	Microfibrillar-associated protein 2 isoform X1.	0.690
FBLN1	THBS1	A0A2Y9QAW1	A0A2Y9PKH8	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	Thrombospondin-1.	0.452
IGFBP3	IGFBP6	A0A2Y9PUR5	A0A2Y9ND47	Insulin-like growth factor-binding protein 3.	Insulin-like growth factor-binding protein 6.	0.515
IGFBP3	THBS1	A0A2Y9PUR5	A0A2Y9PKH8	Insulin-like growth factor-binding protein 3.	Thrombospondin-1.	0.456
IGFBP6	IGFBP3	A0A2Y9ND47	A0A2Y9PUR5	Insulin-like growth factor-binding protein 6.	Insulin-like growth factor-binding protein 3.	0.515
ITGAV	ITGB3	A0A2Y9MPN9	A0A2Y9PCY7	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGAV	THBS1	A0A2Y9MPN9	A0A2Y9PKH8	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	Thrombospondin-1.	0.966
ITGB3	CTSK	A0A2Y9PCY7	A0A2Y9MDR7	Integrin beta; Belongs to the integrin beta chain family.	Cathepsin K isoform X1; Belongs to the peptidase C1 family.	0.552
ITGB3	CTSS	A0A2Y9PCY7	A0A2Y9MDS1	Integrin beta; Belongs to the integrin beta chain family.	Cathepsin S; Belongs to the peptidase C1 family.	0.407
ITGB3	ITGAV	A0A2Y9PCY7	A0A2Y9MPN9	Integrin beta; Belongs to the integrin beta chain family.	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	0.999
ITGB3	THBS1	A0A2Y9PCY7	A0A2Y9PKH8	Integrin beta; Belongs to the integrin beta chain family.	Thrombospondin-1.	0.973
LOXL3	MFAP2	A0A2Y9MCJ3	A0A2Y9QGA8	Lysyl oxidase homolog 3 isoform X1.	Microfibrillar-associated protein 2 isoform X1.	0.417
MFAP2	FBLN1	A0A2Y9QGA8	A0A2Y9QAW1	Microfibrillar-associated protein 2 isoform X1.	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	0.690
MFAP2	LOXL3	A0A2Y9QGA8	A0A2Y9MCJ3	Microfibrillar-associated protein 2 isoform X1.	Lysyl oxidase homolog 3 isoform X1.	0.417
SDC4	THBS1	A0A2Y9PS08	A0A2Y9PKH8	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	Thrombospondin-1.	0.935
THBS1	FBLN1	A0A2Y9PKH8	A0A2Y9QAW1	Thrombospondin-1.	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	0.452
THBS1	IGFBP3	A0A2Y9PKH8	A0A2Y9PUR5	Thrombospondin-1.	Insulin-like growth factor-binding protein 3.	0.456
THBS1	ITGAV	A0A2Y9PKH8	A0A2Y9MPN9	Thrombospondin-1.	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	0.966