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| | RC3H2 | Roquin-2. (1189 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
| | EXOSC3 | Exosome complex component RRP40. (275 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa) |
| | ANXA3 | Annexin. (323 aa) |
| | FER1L5 | Fer-1-like protein 5. (2032 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (146 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5 isoform X1. (1898 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | IL18R1 | Interleukin-18 receptor 1 isoform X1. (539 aa) |
| | KIAA1841 | Uncharacterized protein KIAA1841 homolog isoform X1. (717 aa) |
| | CPLX2 | Complexin-2. (134 aa) |
| | PTK2B | Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa) |
| | DNASE1 | Deoxyribonuclease; Belongs to the DNase I family. (284 aa) |
| | MFNG | beta-1,3-N-acetylglucosaminyltransferase manic fringe isoform X1. (345 aa) |
| | CD180 | CD180 antigen. (661 aa) |
| | GAPT | Protein GAPT. (157 aa) |
| | DOCK2 | Dedicator of cytokinesis protein 2 isoform X1; Belongs to the DOCK family. (1828 aa) |
| | ADA | Adenosine deaminase isoform X1. (416 aa) |
| | LBP | Lipopolysaccharide-binding protein isoform X1. (537 aa) |
| | VAMP2 | Vesicle-associated membrane protein 2. (116 aa) |
| | UNC13D | Protein unc-13 homolog D isoform X1. (1121 aa) |
| | CUNH17orf99 | Uncharacterized protein C17orf99 homolog. (199 aa) |
| | SCNN1B | Amiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | ITGAL | Integrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | MILR1 | Allergin-1 isoform X1. (318 aa) |
| | TYROBP | TYRO protein tyrosine kinase-binding protein isoform X1. (126 aa) |
| | NKG7 | Protein NKG7. (165 aa) |
| | RASGRP1 | RAS guanyl-releasing protein 1 isoform X1. (870 aa) |
| | SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa) |
| | CD19 | B-lymphocyte antigen CD19 isoform X1. (570 aa) |
| | PYCARD | Apoptosis-associated speck-like protein containing a CARD. (195 aa) |
| | CDH17 | Cadherin-17 isoform X1. (832 aa) |
| | GRP | Gastrin-releasing peptide isoform X2. (237 aa) |
| | STXBP3 | Syntaxin-binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa) |
| | EXOSC6 | Exosome complex component MTR3. (272 aa) |
| | KARS | Lysine--tRNA ligase. (625 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (727 aa) |
| | IRF4 | Interferon regulatory factor 4 isoform X1. (451 aa) |
| | BCL3 | B-cell lymphoma 3 protein. (454 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (294 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa) |
| | ERCC1 | DNA excision repair protein ERCC-1 isoform X1. (414 aa) |
| | PLA2G3 | Group 3 secretory phospholipase A2 isoform X1. (516 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (304 aa) |
| | BCR | Breakpoint cluster region protein isoform X1. (1275 aa) |
| | LOC111163131 | Interferon alpha-13-like. (170 aa) |
| | F2RL1 | Proteinase-activated receptor 2. (315 aa) |
| | LOC111163731 | C-C motif chemokine. (93 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | FGL2 | Fibroleukin. (440 aa) |
| | IFNE | Interferon epsilon. (193 aa) |
| | LOC111163130 | Interferon alpha-1-like. (226 aa) |
| | IFI35 | Interferon-induced 35 kDa protein isoform X1. (302 aa) |
| | TBX21 | T-box transcription factor TBX21. (535 aa) |
| | ST3GAL1 | CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa) |
| | SWAP70 | Switch-associated protein 70. (585 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | SLAMF6 | SLAM family member 6 isoform X1. (335 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (900 aa) |
| | CD244 | Natural killer cell receptor 2B4. (369 aa) |
| | S100A13 | Protein S100-A13; Belongs to the S-100 family. (98 aa) |
| | CCR6 | C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1130 aa) |
| | POU2AF1 | POU domain class 2-associating factor 1. (256 aa) |
| | SEMA4A | semaphorin-4A; Belongs to the semaphorin family. (762 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule isoform X1. (378 aa) |
| | LOC111169074 | Dedicator of cytokinesis protein 11 isoform X1; Belongs to the DOCK family. (735 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa) |
| | CX3CR1 | CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa) |
| | IL6R | Interleukin-6 receptor subunit alpha isoform X1. (465 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (799 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase. (378 aa) |
| | EOMES | Eomesodermin homolog isoform X1. (711 aa) |
| | FOXP3 | Forkhead box protein P3. (431 aa) |
| | TNFSF18 | Tumor necrosis factor ligand superfamily member 18. (178 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | SBNO2 | Protein strawberry notch homolog 2 isoform X1. (1383 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | DYSF | Dysferlin isoform X1. (2233 aa) |
| | VAMP7 | Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | SLC11A1 | Natural resistance-associated macrophage protein 1 isoform X1. (546 aa) |
| | RC3H1 | Roquin-1 isoform X1. (1135 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (592 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (602 aa) |
| | NKX2-3 | Homeobox protein Nkx-2.3. (366 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | LOC111171121 | Interferon alpha-1-like. (133 aa) |
| | PTGDR | Prostaglandin D2 receptor. (361 aa) |
| | NMI | N-myc-interactor isoform X1. (309 aa) |
| | LOC111171053 | Dedicator of cytokinesis protein 11-like isoform X1. (456 aa) |
| | LOC111171122 | Interferon alpha-1-like isoform X1. (195 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | CLNK | Cytokine-dependent hematopoietic cell linker isoform X1. (452 aa) |
| | TREX1 | Three-prime repair exonuclease 1. (314 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) |
| | PRKCE | Protein kinase C. (746 aa) |
| | CHGA | chromogranin-A isoform X1. (445 aa) |
| | LOC111176429 | G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | ITFG2 | KICSTOR complex protein ITFG2 isoform X1. (450 aa) |
| | CRACR2A | EF-hand calcium-binding domain-containing protein 4B isoform X1. (722 aa) |
| | DNASE1L3 | Deoxyribonuclease; Belongs to the DNase I family. (304 aa) |
| | RORA | Nuclear receptor ROR-alpha isoform X1. (523 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | AICDA | Single-stranded DNA cytosine deaminase. (208 aa) |
| | PTGDS | prostaglandin-H2 D-isomerase; Belongs to the calycin superfamily. Lipocalin family. (191 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | TSC1 | Hamartin. (1169 aa) |
| | LCP1 | Plastin-2. (627 aa) |
| | LOC111176721 | C-type lectin domain family 4 member E-like. (212 aa) |
| | EXO1 | Exonuclease 1. (801 aa) |
| | HLX | H2.0-like homeobox protein. (488 aa) |
| | DEF6 | Differentially expressed in FDCP 6 homolog isoform X1. (673 aa) |
| | BATF | Basic leucine zipper transcriptional factor ATF-like. (125 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa) |
| | SUCNR1 | Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (318 aa) |
| | ITM2A | Integral membrane protein 2A. (263 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | RAB44 | Ras-related protein Rab-44 isoform X1. (1086 aa) |
| | IRF8 | Interferon regulatory factor 8 isoform X1. (427 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa) |
