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| | CTSC | Dipeptidyl peptidase 1 isoform X1; Belongs to the peptidase C1 family. (463 aa) |
| | BATF | Basic leucine zipper transcriptional factor ATF-like. (125 aa) |
| | NOTCH1 | Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa) |
| | RAB44 | Ras-related protein Rab-44 isoform X1. (1086 aa) |
| | EPHB6 | Ephrin type-B receptor 6 isoform X1. (1010 aa) |
| | ERCC1 | DNA excision repair protein ERCC-1 isoform X1. (414 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (487 aa) |
| | BCL10 | B-cell lymphoma/leukemia 10. (233 aa) |
| | BCL3 | B-cell lymphoma 3 protein. (454 aa) |
| | IRF4 | Interferon regulatory factor 4 isoform X1. (451 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (727 aa) |
| | EXOSC3 | Exosome complex component RRP40. (275 aa) |
| | MASP2 | Mannan-binding lectin serine protease 2 isoform X1; Belongs to the peptidase S1 family. (686 aa) |
| | C9 | Complement component C9. (548 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | C7 | Complement component C7. (843 aa) |
| | C6 | Complement component C6 isoform X1. (934 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5 isoform X1. (1898 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha isoform X1. (459 aa) |
| | IL18R1 | Interleukin-18 receptor 1 isoform X1. (539 aa) |
| | KIAA1841 | Uncharacterized protein KIAA1841 homolog isoform X1. (717 aa) |
| | IL9R | Interleukin-9 receptor. (469 aa) |
| | AIRE | Autoimmune regulator. (553 aa) |
| | C1QBP | Complement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa) |
| | CD55 | Complement decay-accelerating factor isoform X1. (590 aa) |
| | CSF2RB | Cytokine receptor common subunit beta. (902 aa) |
| | MYO1G | Unconventional myosin-Ig isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa) |
| | ADA | Adenosine deaminase isoform X1. (416 aa) |
| | C4BPB | C4b-binding protein beta chain isoform X1. (255 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa) |
| | LOC111184602 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (367 aa) |
| | C4BPA | C4b-binding protein alpha chain isoform X1. (616 aa) |
| | LOC111184601 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (336 aa) |
| | EXOSC6 | Exosome complex component MTR3. (272 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | CD19 | B-lymphocyte antigen CD19 isoform X1. (570 aa) |
| | IL4R | Interleukin-4 receptor subunit alpha isoform X1. (831 aa) |
| | IL21R | Interleukin-21 receptor isoform X2. (560 aa) |
| | ZP3 | Zona pellucida sperm-binding protein 3. (421 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | PRF1 | Perforin-1. (555 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | UNC13D | Protein unc-13 homolog D isoform X1. (1121 aa) |
| | MEF2C | Myocyte-specific enhancer factor 2C isoform X6. (483 aa) |
| | LOC111184729 | Membrane cofactor protein-like isoform X1. (411 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (304 aa) |
| | C1QA | Complement C1q subcomponent subunit A. (245 aa) |
| | C1QC | Complement C1q subcomponent subunit C. (245 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | TRAF3IP2 | Adapter protein CIKS isoform X1. (564 aa) |
| | CTSH | Pro-cathepsin H; Belongs to the peptidase C1 family. (335 aa) |
| | C1QB | Complement C1q subcomponent subunit B. (290 aa) |
| | EMP2 | Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa) |
| | LOC111165935 | Ras-like protein isoform X1. (285 aa) |
| | BACH2 | Transcription regulator protein BACH2. (841 aa) |
| | LOC111166100 | Complement C3-like isoform X1. (1706 aa) |
| | LOC111166170 | C-type lectin domain family 4 member G-like isoform X1. (313 aa) |
| | TBX21 | T-box transcription factor TBX21. (535 aa) |
| | SWAP70 | Switch-associated protein 70. (585 aa) |
| | PHB | Prohibitin. (272 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | SLAMF6 | SLAM family member 6 isoform X1. (335 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa) |
| | C3 | Complement C3 isoform X1. (1695 aa) |
| | CD8A | T-cell surface glycoprotein CD8 alpha chain isoform X1. (239 aa) |
| | CCR6 | C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa) |
| | BTN3A3 | Butyrophilin subfamily 3 member A3 isoform X1. (630 aa) |
| | SEMA4A | semaphorin-4A; Belongs to the semaphorin family. (762 aa) |
| | IL6R | Interleukin-6 receptor subunit alpha isoform X1. (465 aa) |
| | FOXP3 | Forkhead box protein P3. (431 aa) |
| | IRF7 | Interferon regulatory factor 7 isoform X1. (473 aa) |
| | CD40 | Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | LOC111170700 | Complement C4-like isoform X1. (1740 aa) |
| | RFTN1 | Raftlin. (567 aa) |
| | IL18BP | Interleukin-18-binding protein isoform X1. (204 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (592 aa) |
| | GZMM | Granzyme M; Belongs to the peptidase S1 family. (257 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (602 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | MBL2 | LOW QUALITY PROTEIN: mannose-binding protein C. (244 aa) |
| | KLHL6 | Kelch-like protein 6 isoform X1. (621 aa) |
| | C2 | Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa) |
| | INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | TREX1 | Three-prime repair exonuclease 1. (314 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) |
| | NFKB2 | Nuclear factor NF-kappa-B p100 subunit isoform X1. (900 aa) |
| | C8B | Complement component C8 beta chain isoform X1. (590 aa) |
| | PRKCD | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa) |
| | C8A | Complement component C8 alpha chain isoform X1. (589 aa) |
| | C1S | Complement C1s subcomponent; Belongs to the peptidase S1 family. (695 aa) |
| | CRACR2A | EF-hand calcium-binding domain-containing protein 4B isoform X1. (722 aa) |
| | C1R | Complement C1r subcomponent isoform X1; Belongs to the peptidase S1 family. (713 aa) |
| | RORA | Nuclear receptor ROR-alpha isoform X1. (523 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | AICDA | Single-stranded DNA cytosine deaminase. (208 aa) |
| | TNFSF13B | Tumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (283 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | C5 | Complement C5 isoform X1. (1677 aa) |
| | EXO1 | Exonuclease 1. (801 aa) |
| | HLX | H2.0-like homeobox protein. (488 aa) |
| | LOC111178659 | Antigen peptide transporter 2-like isoform X4. (758 aa) |
| | DEF6 | Differentially expressed in FDCP 6 homolog isoform X1. (673 aa) |
| | MORN5 | MORN repeat-containing protein 5 isoform X1. (172 aa) |
| | BTK | Tyrosine-protein kinase. (687 aa) |
| | CARD9 | Caspase recruitment domain-containing protein 9 isoform X1. (539 aa) |
