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| | THOC5 | THO complex subunit 5 homolog isoform X1. (683 aa) |
| | LOC111163131 | Interferon alpha-13-like. (170 aa) |
| | CCL19 | C-C motif chemokine. (159 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (215 aa) |
| | F2RL1 | Proteinase-activated receptor 2. (315 aa) |
| | PKNOX1 | Homeobox protein PKNOX1 isoform X1. (436 aa) |
| | PATZ1 | POZ-, AT hook-, and zinc finger-containing protein 1 isoform X1. (687 aa) |
| | RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) |
| | IRF2BP2 | Interferon regulatory factor 2-binding protein 2 isoform X1. (592 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa) |
| | TRAF3IP2 | Adapter protein CIKS isoform X1. (564 aa) |
| | CMTM7 | CKLF-like MARVEL transmembrane domain-containing protein 7 isoform X4. (214 aa) |
| | LOC111165315 | Adhesion G protein-coupled receptor G3-like isoform X1; Belongs to the G-protein coupled receptor 2 family. (468 aa) |
| | LOC111165316 | Adhesion G protein-coupled receptor G3-like isoform X1; Belongs to the G-protein coupled receptor 2 family. (607 aa) |
| | IFNE | Interferon epsilon. (193 aa) |
| | TPD52 | Tumor protein D52 isoform X1. (247 aa) |
| | LOC111163130 | Interferon alpha-1-like. (226 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | CEBPE | CCAAT/enhancer-binding protein. (281 aa) |
| | HECTD1 | E3 ubiquitin-protein ligase HECTD1 isoform X1. (2610 aa) |
| | LOC111165062 | WNT1-inducible-signaling pathway protein 1-like. (398 aa) |
| | PSMB11 | Proteasome subunit beta. (291 aa) |
| | ZNF683 | LOW QUALITY PROTEIN: tissue-resident T-cell transcription regulator protein ZNF683. (505 aa) |
| | LY6D | Lymphocyte antigen 6D. (128 aa) |
| | TOX | Thymocyte selection-associated high mobility group box protein TOX isoform X1. (517 aa) |
| | VAV1 | Proto-oncogene vav isoform X1. (845 aa) |
| | L3MBTL3 | Lethal(3)malignant brain tumor-like protein 3 isoform X3. (779 aa) |
| | LOC111165710 | LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein; Belongs to the MHC class I family. (254 aa) |
| | LOC111164034 | LOW QUALITY PROTEIN: THO complex subunit 5 homolog. (625 aa) |
| | IKZF3 | Zinc finger protein Aiolos isoform X1. (509 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) |
| | LOC111166170 | C-type lectin domain family 4 member G-like isoform X1. (313 aa) |
| | LOC111166174 | Uncharacterized protein LOC111166174. (283 aa) |
| | TBX21 | T-box transcription factor TBX21. (535 aa) |
| | ST3GAL1 | CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa) |
| | STAT5A | Signal transducer and activator of transcription. (818 aa) |
| | LOC111166483 | Signal transducer and activator of transcription. (787 aa) |
| | CCR7 | C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | GPC3 | Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa) |
| | JUNB | Transcription factor jun-B. (347 aa) |
| | THEMIS | Protein THEMIS isoform X1. (652 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa) |
| | LYL1 | Protein lyl-1. (279 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain. (171 aa) |
| | LOC111166812 | Cathepsin L1; Belongs to the peptidase C1 family. (334 aa) |
| | SLAMF6 | SLAM family member 6 isoform X1. (335 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain. (197 aa) |
| | GBA | Glucosylceramidase. (585 aa) |
| | IL7 | Interleukin-7 isoform X1. (226 aa) |
| | LYN | Tyrosine-protein kinase. (518 aa) |
| | GON4L | GON-4-like protein isoform X1. (2240 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (795 aa) |
| | CTSL | Cathepsin L1; Belongs to the peptidase C1 family. (333 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | CD8A | T-cell surface glycoprotein CD8 alpha chain isoform X1. (239 aa) |
| | CCR6 | C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | NFIL3 | Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T- cells. Competes for the same consensus-binding site with PAR DNA- bi [...] (462 aa) |
| | PLCL2 | Phosphoinositide phospholipase C. (1130 aa) |
| | ZBTB7A | Zinc finger and BTB domain-containing protein 7A. (587 aa) |
| | SASH3 | SAM and SH3 domain-containing protein 3. (380 aa) |
| | PTPRC | Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa) |
| | POU2AF1 | POU domain class 2-associating factor 1. (256 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa) |
| | ZBTB7B | Zinc finger and BTB domain-containing protein 7B. (541 aa) |
| | SEMA4A | semaphorin-4A; Belongs to the semaphorin family. (762 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule isoform X1. (378 aa) |
| | CITED2 | Cbp/p300-interacting transactivator 2. (272 aa) |
| | LOC111169074 | Dedicator of cytokinesis protein 11 isoform X1; Belongs to the DOCK family. (735 aa) |
| | PIR | Pirin isoform X1. (323 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | DHRS7B | Dehydrogenase/reductase SDR family member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa) |
| | IL6R | Interleukin-6 receptor subunit alpha isoform X1. (465 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (799 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase. (378 aa) |
| | PRR7 | Proline-rich protein 7. (269 aa) |
| | AZI2 | 5-azacytidine-induced protein 2. (393 aa) |
| | EOMES | Eomesodermin homolog isoform X1. (711 aa) |
| | FOXP3 | Forkhead box protein P3. (431 aa) |
| | GATA1 | Erythroid transcription factor isoform X1. (426 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | JAGN1 | Protein jagunal homolog 1. (183 aa) |
| | SBNO2 | Protein strawberry notch homolog 2 isoform X1. (1383 aa) |
| | IL2RG | Cytokine receptor common subunit gamma isoform X1. (381 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | CARD11 | Caspase recruitment domain-containing protein 11 isoform X1. (1154 aa) |
| | TET2 | Methylcytosine dioxygenase TET2. (1997 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (518 aa) |
| | FZD5 | Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa) |
| | NHEJ1 | Non-homologous end-joining factor 1 isoform X1. (299 aa) |
| | RC3H1 | Roquin-1 isoform X1. (1135 aa) |
| | RABL3 | Rab-like protein 3. (236 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28. (265 aa) |
| | EFNA2 | ephrin-A2; Belongs to the ephrin family. (214 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (602 aa) |
| | NKX2-3 | Homeobox protein Nkx-2.3. (366 aa) |
| | FARP2 | FERM, RhoGEF and pleckstrin domain-containing protein 2 isoform X1. (1116 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | NRROS | Negative regulator of reactive oxygen species isoform X1. (699 aa) |
| | LOC111171121 | Interferon alpha-1-like. (133 aa) |
| | OCSTAMP | LOW QUALITY PROTEIN: osteoclast stimulatory transmembrane protein. (566 aa) |
| | BMP4 | Bone morphogenetic protein 4 isoform X2. (408 aa) |
| | RHOH | Rho-related GTP-binding protein RhoH. (191 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | STK11 | Serine/threonine-protein kinase STK11 isoform X1. (544 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (308 aa) |
| | GAB3 | GRB2-associated-binding protein 3 isoform X1. (587 aa) |
| | ZBTB1 | Zinc finger and BTB domain-containing protein 1. (713 aa) |
| | ATP6AP1 | V-type proton ATPase subunit S1. (469 aa) |
| | LOC111171053 | Dedicator of cytokinesis protein 11-like isoform X1. (456 aa) |
| | LOC111171122 | Interferon alpha-1-like isoform X1. (195 aa) |
| | STAT6 | Signal transducer and activator of transcription. (847 aa) |
| | MITF | Microphthalmia-associated transcription factor isoform X1. (526 aa) |
| | LMBR1L | Protein LMBR1L isoform X1; Belongs to the LIMR family. (521 aa) |
| | FZD7 | Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | BAP1 | Ubiquitin carboxyl-terminal hydrolase. (729 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | SRP54 | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa) |
| | TCTA | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. (106 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | FLT3 | Receptor-type tyrosine-protein kinase FLT3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) |
| | PDE1B | Phosphodiesterase. (542 aa) |
| | SP3 | Transcription factor Sp3 isoform X1. (796 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | ZFP36L1 | mRNA decay activator protein ZFP36L1. (338 aa) |
| | GPR68 | Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | JUN | Transcription factor AP-1; Belongs to the bZIP family. (343 aa) |
| | TUSC2 | Tumor suppressor candidate 2. (110 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1233 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | YY1 | Transcriptional repressor protein YY1. (412 aa) |
| | LOC111176429 | G-protein coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | ITFG2 | KICSTOR complex protein ITFG2 isoform X1. (450 aa) |
| | LTBR | Tumor necrosis factor receptor superfamily member 3. (421 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | BCL11B | B-cell lymphoma/leukemia 11B isoform X1. (903 aa) |
| | FOXP1 | Forkhead box protein P1 isoform X1. (673 aa) |
| | CRACR2A | EF-hand calcium-binding domain-containing protein 4B isoform X1. (722 aa) |
| | LRRC8A | Volume-regulated anion channel subunit LRRC8A isoform X1. (854 aa) |
| | DCAF1 | DDB1- and CUL4-associated factor 1 isoform X1. (1540 aa) |
| | GIMAP1 | GTPase IMAP family member 1 isoform X1. (318 aa) |
| | NRARP | Notch-regulated ankyrin repeat-containing protein. (114 aa) |
| | CCR9 | C-C chemokine receptor type 9 isoform X1; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | APP | Amyloid beta A4 protein isoform X1. (767 aa) |
| | LBR | lamin-B receptor. (621 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa) |
| | ONECUT1 | One cut domain family member. (465 aa) |
| | RORA | Nuclear receptor ROR-alpha isoform X1. (523 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | ZFP36L2 | mRNA decay activator protein ZFP36L2. (493 aa) |
| | IREB2 | Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family. (964 aa) |
| | GAS6 | Growth arrest-specific protein 6. (671 aa) |
| | TNFSF13B | Tumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (283 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | TSC1 | Hamartin. (1169 aa) |
| | GPR18 | N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (338 aa) |
| | LCK | Tyrosine-protein kinase. (509 aa) |
| | LOC111176721 | C-type lectin domain family 4 member E-like. (212 aa) |
| | HLX | H2.0-like homeobox protein. (488 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer isoform X1. (239 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf isoform X1. (762 aa) |
| | BTK | Tyrosine-protein kinase. (687 aa) |
| | SRF | Serum response factor isoform X2. (535 aa) |
| | BATF | Basic leucine zipper transcriptional factor ATF-like. (125 aa) |
| | LEPR | Leptin receptor isoform X1. (917 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa) |
| | ITM2A | Integral membrane protein 2A. (263 aa) |
| | ZFPM1 | Zinc finger protein ZFPM1 isoform X1. (1069 aa) |
| | RUNX2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (524 aa) |
| | LOC111176900 | GTPase IMAP family member 5-like isoform X1. (332 aa) |
| | FUT7 | Alpha-(1,3)-fucosyltransferase 7. (342 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | RAB44 | Ras-related protein Rab-44 isoform X1. (1086 aa) |
| | GLO1 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (184 aa) |
| | IRF8 | Interferon regulatory factor 8 isoform X1. (427 aa) |
| | TSPAN2 | Tetraspanin. (221 aa) |
| | EZH2 | Histone-lysine N-methyltransferase EZH2 isoform X1. (747 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | RC3H2 | Roquin-2. (1189 aa) |
| | TNFSF8 | Tumor necrosis factor ligand superfamily member 8 isoform X1; Belongs to the tumor necrosis factor family. (234 aa) |
| | LOC111178963 | LOW QUALITY PROTEIN: butyrophilin-like protein 1. (513 aa) |
| | DCSTAMP | LOW QUALITY PROTEIN: dendritic cell-specific transmembrane protein. (510 aa) |
| | SNX10 | Sorting nexin-10 isoform X1. (201 aa) |
| | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa) |
| | LOC111178088 | Protein artemis-like isoform X1. (709 aa) |
| | CD79A | B-cell antigen receptor complex-associated protein alpha chain. (223 aa) |
| | AXL | LOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (294 aa) |
| | CEBPG | CCAAT/enhancer-binding protein gamma. (149 aa) |
| | CDK6 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa) |
| | TNFRSF11A | Tumor necrosis factor receptor superfamily member 11A isoform X1. (551 aa) |
| | LOC111179199 | Serotransferrin-like; Belongs to the transferrin family. (706 aa) |
| | BCL3 | B-cell lymphoma 3 protein. (454 aa) |
| | IRF4 | Interferon regulatory factor 4 isoform X1. (451 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | SOX4 | Transcription factor SOX. (477 aa) |
| | CEBPA | CCAAT/enhancer-binding protein alpha. (355 aa) |
| | RRAS | Ras-related protein R-Ras isoform X1. (251 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | TYRO3 | Tyrosine-protein kinase receptor TYRO3 isoform X3. (896 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa) |
| | CBFA2T3 | Protein CBFA2T3 isoform X1. (648 aa) |
| | CD83 | CD83 antigen isoform X1. (195 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (233 aa) |
| | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa) |
| | RAG2 | V(D)J recombination-activating protein 2. (527 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | CDH17 | Cadherin-17 isoform X1. (832 aa) |
| | CD19 | B-lymphocyte antigen CD19 isoform X1. (570 aa) |
| | LOC111179942 | Golgi pH regulator isoform X1. (455 aa) |
| | NOTCH2 | Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa) |
| | PTPN22 | Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (623 aa) |
| | FZD9 | Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (590 aa) |
| | FNIP1 | Folliculin-interacting protein 1 isoform X1. (1165 aa) |
| | IRF1 | Interferon regulatory factor. (322 aa) |
| | TCF7 | Transcription factor 7 isoform X1. (415 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa) |
| | FASN | Fatty acid synthase isoform X1. (2680 aa) |
| | JMJD6 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6. (414 aa) |
| | CD79B | B-cell antigen receptor complex-associated protein beta chain isoform X1. (230 aa) |
| | ITK | Tyrosine-protein kinase. (620 aa) |
| | TMEM176B | Transmembrane protein 176B. (265 aa) |
| | CALCR | Calcitonin receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (524 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor. (144 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (767 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (735 aa) |
| | CLCF1 | Cardiotrophin-like cytokine factor 1 isoform X1. (281 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | CUNH17orf99 | Uncharacterized protein C17orf99 homolog. (199 aa) |
| | LOC111183908 | B-lymphocyte antigen CD20-like. (303 aa) |
| | IKZF1 | DNA-binding protein Ikaros isoform X1. (556 aa) |
| | BATF3 | Basic leucine zipper transcriptional factor ATF-like 3. (122 aa) |
| | MAFB | Transcription factor MafB. (323 aa) |
| | CSF1R | Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa) |
| | SRC | Tyrosine-protein kinase. (562 aa) |
| | PAX1 | Paired box protein Pax-1. (448 aa) |
| | CD109 | CD109 antigen isoform X1. (1440 aa) |
| | BLK | Tyrosine-protein kinase. (501 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa) |
| | BATF2 | Basic leucine zipper transcriptional factor ATF-like 2 isoform X1. (269 aa) |
| | ADA | Adenosine deaminase isoform X1. (416 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa) |
| | GLI3 | Transcriptional activator GLI3 isoform X1. (1587 aa) |
| | DOCK2 | Dedicator of cytokinesis protein 2 isoform X1; Belongs to the DOCK family. (1828 aa) |
| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1497 aa) |
| | CHD7 | chromodomain-helicase-DNA-binding protein 7 isoform X1. (3050 aa) |
| | GPS2 | G protein pathway suppressor 2. (327 aa) |
| | FOXN1 | Forkhead box protein N1. (645 aa) |
| | SOX13 | Transcription factor SOX-13. (644 aa) |
| | ZBTB46 | Zinc finger and BTB domain-containing protein 46. (590 aa) |
| | GAB2 | GRB2-associated-binding protein 2 isoform X1. (678 aa) |
| | PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa) |
| | AIRE | Autoimmune regulator. (553 aa) |
| | MFNG | beta-1,3-N-acetylglucosaminyltransferase manic fringe isoform X1. (345 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | PTK2B | Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa) |
| | IL31RA | LOW QUALITY PROTEIN: interleukin-31 receptor subunit alpha. (520 aa) |
| | LRRK1 | Leucine-rich repeat serine/threonine-protein kinase 1. (2015 aa) |
| | IL18R1 | Interleukin-18 receptor 1 isoform X1. (539 aa) |
| | LOC111187417 | Tyrosine-protein kinase. (612 aa) |
| | NF1 | Neurofibromin isoform X1. (2873 aa) |
| | PREX1 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X1. (1653 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha isoform X1. (459 aa) |
| | TMEM98 | Transmembrane protein 98. (226 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (146 aa) |
| | EPHA2 | Ephrin type-A receptor 2. (975 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | NCAPH2 | Condensin-2 complex subunit H2 isoform X1. (679 aa) |
| | TOB2 | Protein Tob2. (343 aa) |
| | FBXO7 | F-box only protein 7 isoform X1. (523 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa) |
| | LOC111187154 | Ephrin type-A receptor 2-like. (171 aa) |
| | MERTK | Tyrosine-protein kinase Mer. (999 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (180 aa) |
| | MYH9 | Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa) |
| | Ob | Leptin isoform X1. (167 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
