STRINGSTRING
C3AR1 C3AR1 TRPV4 TRPV4 CREB3 CREB3 CXCL13 CXCL13 IL1R1 IL1R1 CMKLR1 CMKLR1 TNFRSF18 TNFRSF18 PIK3R1 PIK3R1 CXCL10 CXCL10 PTK2B PTK2B C1QBP C1QBP RAC2 RAC2 DEFB124 DEFB124 LBP LBP VEGFB VEGFB MCU MCU CSF1R CSF1R THBS4 THBS4 FADD FADD CCL24 CCL24 CORO1A CORO1A CD74 CD74 CXCL14 CXCL14 ZP3 ZP3 ZNF580 ZNF580 MAPK3 MAPK3 ITGB3 ITGB3 CSF1 CSF1 PYCARD PYCARD NEDD9 NEDD9 C5AR1 C5AR1 TREM2 TREM2 IL34 IL34 ABL1 ABL1 FUT7 FUT7 WNK1 WNK1 F7 F7 PLA2G7 PLA2G7 ADAM10 ADAM10 DEF6 DEF6 AKIRIN1 AKIRIN1 GAS6 GAS6 PTN PTN LGMN LGMN APP APP DOCK8 DOCK8 RARRES2 RARRES2 IL12A IL12A CCR2 CCR2 ANO6 ANO6 DNM1L DNM1L PGF PGF RHOA RHOA LGALS3 LGALS3 EDN2 EDN2 HABP2 HABP2 WNT5A WNT5A JAM2 JAM2 ADAM8 ADAM8 CCR1 CCR1 NCKAP1L NCKAP1L VEGFC VEGFC GPSM3 GPSM3 STK39 STK39 MADCAM1 MADCAM1 LOC111172293 LOC111172293 CXCL12 CXCL12 PRSS56 PRSS56 CCL20 CCL20 LOC111171403 LOC111171403 MSTN MSTN AGER AGER TMEM102 TMEM102 AIF1 AIF1 FUT4 FUT4 VEGFD VEGFD TNFSF18 TNFSF18 THY1 THY1 CD99L2 CD99L2 CX3CR1 CX3CR1 CALR CALR MOSPD2 MOSPD2 SELP SELP XG XG SLAMF1 SLAMF1 RIPOR2 RIPOR2 CD99 CD99 CCR6 CCR6 JAM3 JAM3 LYVE1 LYVE1 XCL1 XCL1 PAWR PAWR S100A14 S100A14 PLVAP PLVAP OXSR1 OXSR1 CCR7 CCR7 SWAP70 SWAP70 MMP14 MMP14 TNFSF14 TNFSF14 CCL5 CCL5 CCL27 CCL27 LOC111163731 LOC111163731 CCL21 CCL21 MAPK1 MAPK1 F2RL1 F2RL1 CCL19 CCL19
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C3AR1C3a anaphylatoxin chemotactic receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (498 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (370 aa)
CXCL13C-X-C motif chemokine 13. (109 aa)
IL1R1Interleukin-1 receptor type 1 isoform X1. (686 aa)
CMKLR1Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
TNFRSF18LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 18. (231 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
CXCL10C-X-C motif chemokine. (103 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
C1QBPComplement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X2. (192 aa)
DEFB124Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (70 aa)
LBPLipopolysaccharide-binding protein isoform X1. (537 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (209 aa)
MCUCalcium uniporter protein, mitochondrial isoform X1. (371 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
THBS4Thrombospondin-4. (961 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
CCL24C-C motif chemokine 24. (119 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
CXCL14C-X-C motif chemokine 14. (99 aa)
ZP3Zona pellucida sperm-binding protein 3. (421 aa)
ZNF580Zinc finger protein 580 isoform X1. (182 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD. (195 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
IL34Interleukin-34. (235 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
FUT7Alpha-(1,3)-fucosyltransferase 7. (342 aa)
WNK1Serine/threonine-protein kinase WNK1 isoform X1. (2825 aa)
F7Coagulation factor VII isoform X1. (447 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (443 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
DEF6Differentially expressed in FDCP 6 homolog isoform X1. (673 aa)
AKIRIN1Akirin-1 isoform X1. (206 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
PTNPleiotrophin isoform X1. (168 aa)
LGMNLegumain. (433 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
DOCK8Dedicator of cytokinesis protein 8 isoform X1; Belongs to the DOCK family. (2098 aa)
RARRES2Retinoic acid receptor responder protein 2. (166 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
CCR2C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ANO6Anoctamin. (951 aa)
DNM1LDynamin-1-like protein isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (763 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
RHOATransforming protein RhoA. (193 aa)
LGALS3Galectin. (256 aa)
EDN2Endothelin-2. (147 aa)
HABP2Hyaluronan-binding protein 2. (433 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
JAM2Junctional adhesion molecule B isoform X1. (350 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
CCR1C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
GPSM3G-protein-signaling modulator 3. (162 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase isoform X1. (539 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1. (406 aa)
LOC111172293Hyaluronan-binding protein 2. (553 aa)
CXCL12Stromal cell-derived factor 1 isoform X1; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
PRSS56LOW QUALITY PROTEIN: serine protease 56; Belongs to the peptidase S1 family. (606 aa)
CCL20C-C motif chemokine. (97 aa)
LOC111171403LOW QUALITY PROTEIN: transmembrane protein 102-like. (288 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (631 aa)
TMEM102LOW QUALITY PROTEIN: transmembrane protein 102. (506 aa)
AIF1Allograft inflammatory factor 1 isoform X1. (162 aa)
FUT4Alpha-(1,3)-fucosyltransferase 4. (458 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
TNFSF18Tumor necrosis factor ligand superfamily member 18. (178 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
CD99L2CD99 antigen-like protein 2 isoform X1. (300 aa)
CX3CR1CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
CALRCalreticulin. (417 aa)
MOSPD2Motile sperm domain-containing protein 2 isoform X1. (518 aa)
SELPP-selectin isoform X1. (768 aa)
XGGlycoprotein Xg. (140 aa)
SLAMF1Signaling lymphocytic activation molecule isoform X1. (378 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X2. (1048 aa)
CD99CD99 antigen isoform X1. (200 aa)
CCR6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
JAM3Junctional adhesion molecule C. (301 aa)
LYVE1Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X1. (322 aa)
XCL1Lymphotactin. (111 aa)
PAWRPRKC apoptosis WT1 regulator protein. (345 aa)
S100A14Protein S100-A14; Belongs to the S-100 family. (104 aa)
PLVAPPlasmalemma vesicle-associated protein isoform X1. (453 aa)
OXSR1Serine/threonine-protein kinase OSR1. (523 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
SWAP70Switch-associated protein 70. (585 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform X1. (241 aa)
CCL5C-C motif chemokine. (91 aa)
CCL27LOW QUALITY PROTEIN: C-C motif chemokine 27. (117 aa)
LOC111163731C-C motif chemokine. (93 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
F2RL1Proteinase-activated receptor 2. (315 aa)
CCL19C-C motif chemokine. (159 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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