STRINGSTRING
CD37 CD37 BCR BCR PLA2G2F PLA2G2F FGR FGR RHBDD3 RHBDD3 SOCS1 SOCS1 TWSG1 TWSG1 PTPN2 PTPN2 GLMN GLMN PLA2G2D PLA2G2D PAG1 PAG1 FGL2 FGL2 ADORA2A ADORA2A LOC111166170 LOC111166170 TBX21 TBX21 PKN1 PKN1 NR1D1 NR1D1 TNFAIP3 TNFAIP3 ENPP3 ENPP3 SYT11 SYT11 CD84 CD84 LYN LYN LOC111167004 LOC111167004 TIGIT TIGIT PAWR PAWR ILDR2 ILDR2 ERBB2 ERBB2 CRTAM CRTAM LDLR LDLR ATM ATM RIPOR2 RIPOR2 ZBTB7B ZBTB7B HFE HFE PGLYRP2 PGLYRP2 VSIG4 VSIG4 LOXL3 LOXL3 TNFAIP8L2 TNFAIP8L2 GPER1 GPER1 FOXP3 FOXP3 CD80 CD80 DUSP3 DUSP3 TNFRSF13B TNFRSF13B SOX11 SOX11 CD86 CD86 RC3H1 RC3H1 MAD1L1 MAD1L1 DLG1 DLG1 IHH IHH MARCH7 MARCH7 BCL6 BCL6 GRN GRN BMP4 BMP4 CTLA4 CTLA4 LRFN5 LRFN5 SFRP1 SFRP1 INPP5D INPP5D CLNK CLNK NCKAP1L NCKAP1L PARP3 PARP3 ANXA1 ANXA1 ARG2 ARG2 SOCS5 SOCS5 CD274 CD274 ZC3H12A ZC3H12A FGL1 FGL1 IDO1 IDO1 LOC111175407 LOC111175407 PDCD1LG2 PDCD1LG2 SHH SHH SAMSN1 SAMSN1 NRARP NRARP PIBF1 PIBF1 PTPN6 PTPN6 HLX HLX LOC111178657 LOC111178657 BTK BTK LRRC1 LRRC1 LAG3 LAG3 LOC111176900 LOC111176900 FOXF1 FOXF1 RC3H2 RC3H2 FAM19A3 FAM19A3 BANK1 BANK1 IL20RB IL20RB AXL AXL ADGRF5 ADGRF5 TGFB1 TGFB1 IL4I1 IL4I1 TNFRSF21 TNFRSF21 TYRO3 TYRO3 THOC1 THOC1 PTPN22 PTPN22 SOCS6 SOCS6 IRF1 IRF1 SMAD7 SMAD7 GPNMB GPNMB FOXJ1 FOXJ1 TYROBP TYROBP MILR1 MILR1 CD300LF CD300LF LOC111182867 LOC111182867 CD74 CD74 TMEM248 TMEM248 TBC1D10C TBC1D10C FER FER NR1H3 NR1H3 PRKAR1A PRKAR1A LAX1 LAX1 NDFIP1 NDFIP1 BPI BPI VSIR VSIR DLG5 DLG5 TSPAN32 TSPAN32 BLK BLK IL10 IL10 RASSF5 RASSF5 LRRC32 LRRC32 DLG2 DLG2 CBLB CBLB ITCH ITCH GLI3 GLI3 ZBTB46 ZBTB46 CST7 CST7 LGALS9 LGALS9 CEBPB CEBPB ZC3H8 ZC3H8 PELI1 PELI1 TMEM131L TMEM131L FBXO7 FBXO7 MERTK MERTK CD200 CD200
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD37Tetraspanin. (370 aa)
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
PLA2G2FPhospholipase A(2). (300 aa)
FGRTyrosine-protein kinase. (526 aa)
RHBDD3Rhomboid domain-containing protein 3. (386 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type 2 isoform X3. (474 aa)
GLMNGlomulin. (592 aa)
PLA2G2DPhospholipase A(2). (161 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 isoform X2. (436 aa)
FGL2Fibroleukin. (440 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (408 aa)
LOC111166170C-type lectin domain family 4 member G-like isoform X1. (313 aa)
TBX21T-box transcription factor TBX21. (535 aa)
PKN1Serine/threonine-protein kinase N1 isoform X1. (950 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (785 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (900 aa)
SYT11Synaptotagmin-11 isoform X1. (428 aa)
CD84SLAM family member 5 isoform X1. (341 aa)
LYNTyrosine-protein kinase. (518 aa)
LOC111167004LOW QUALITY PROTEIN: peptidoglycan recognition protein 3-like. (277 aa)
TIGITT-cell immunoreceptor with Ig and ITIM domains. (243 aa)
PAWRPRKC apoptosis WT1 regulator protein. (345 aa)
ILDR2Immunoglobulin-like domain-containing receptor 2. (639 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
CRTAMCytotoxic and regulatory T-cell molecule isoform X1. (391 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X2. (1048 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B. (541 aa)
HFEHereditary hemochromatosis protein isoform X1; Belongs to the MHC class I family. (356 aa)
PGLYRP2N-acetylmuramoyl-L-alanine amidase isoform X1. (581 aa)
VSIG4V-set and immunoglobulin domain-containing protein 4. (399 aa)
LOXL3Lysyl oxidase homolog 3 isoform X1. (772 aa)
TNFAIP8L2Tumor necrosis factor alpha-induced protein 8-like protein 2 isoform X1. (204 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
FOXP3Forkhead box protein P3. (431 aa)
CD80T-lymphocyte activation antigen CD80 isoform X1. (295 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
TNFRSF13BTumor necrosis factor receptor superfamily member 13B isoform X1. (284 aa)
SOX11Transcription factor SOX. (454 aa)
CD86T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
RC3H1Roquin-1 isoform X1. (1135 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform X2. (735 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
MARCH7E3 ubiquitin-protein ligase MARCH7 isoform X1. (717 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
GRNGranulins isoform X1. (587 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
CTLA4Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
LRFN5Leucine-rich repeat and fibronectin type-III domain-containing protein 5. (719 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
CLNKCytokine-dependent hematopoietic cell linker isoform X1. (452 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
PARP3Poly [ADP-ribose] polymerase. (586 aa)
ANXA1Annexin. (346 aa)
ARG2Arginase. (354 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
CD274Programmed cell death 1 ligand 1 isoform X2. (312 aa)
ZC3H12AEndoribonuclease ZC3H12A. (583 aa)
FGL1Fibrinogen-like protein 1. (315 aa)
IDO1Indoleamine 2,3-dioxygenase 1 isoform X1. (410 aa)
LOC111175407Amine oxidase. (524 aa)
PDCD1LG2Programmed cell death 1 ligand 2 isoform X1. (337 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
SAMSN1SAM domain-containing protein SAMSN-1. (373 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
PIBF1Progesterone-induced-blocking factor 1 isoform X1. (757 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
HLXH2.0-like homeobox protein. (488 aa)
LOC111178657Leucine-rich repeat-containing protein 1-like isoform X1. (174 aa)
BTKTyrosine-protein kinase. (687 aa)
LRRC1Leucine-rich repeat-containing protein 1. (395 aa)
LAG3Lymphocyte activation gene 3 protein. (493 aa)
LOC111176900GTPase IMAP family member 5-like isoform X1. (332 aa)
FOXF1Forkhead box protein F1. (375 aa)
RC3H2Roquin-2. (1189 aa)
FAM19A3Protein FAM19A3 isoform X1. (146 aa)
BANK1B-cell scaffold protein with ankyrin repeats isoform X1. (785 aa)
IL20RBInterleukin-20 receptor subunit beta isoform X1. (342 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
ADGRF5Adhesion G protein-coupled receptor F5 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1408 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
IL4I1L-amino-acid oxidase isoform X1. (653 aa)
TNFRSF21Tumor necrosis factor receptor superfamily member 21 isoform X3. (701 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3 isoform X3. (896 aa)
THOC1THO complex subunit 1. (657 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
IRF1Interferon regulatory factor. (322 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
GPNMBTransmembrane glycoprotein NMB. (553 aa)
FOXJ1Forkhead box protein J1. (422 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
MILR1Allergin-1 isoform X1. (318 aa)
CD300LFCMRF35-like molecule 1 isoform X1. (310 aa)
LOC111182867CMRF35-like molecule 8 isoform X1. (313 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
TMEM248Transmembrane protein 248 isoform X7. (971 aa)
TBC1D10CCarabin isoform X1. (458 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
LAX1LOW QUALITY PROTEIN: lymphocyte transmembrane adapter 1. (430 aa)
NDFIP1NEDD4 family-interacting protein 1. (221 aa)
BPIBactericidal permeability-increasing protein isoform X1. (483 aa)
VSIRV-type immunoglobulin domain-containing suppressor of T-cell activation. (311 aa)
DLG5Disks large homolog 5 isoform X1; Belongs to the MAGUK family. (1980 aa)
TSPAN32Tetraspanin-32 isoform X1; Belongs to the tetraspanin (TM4SF) family. (571 aa)
BLKTyrosine-protein kinase. (501 aa)
IL10Interleukin-10. (178 aa)
RASSF5Ras association domain-containing protein 5 isoform X1. (422 aa)
LRRC32Leucine-rich repeat-containing protein 32 isoform X1. (676 aa)
DLG2Disks large homolog 2 isoform X1. (994 aa)
CBLBE3 ubiquitin-protein ligase CBL-B. (983 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
GLI3Transcriptional activator GLI3 isoform X1. (1587 aa)
ZBTB46Zinc finger and BTB domain-containing protein 46. (590 aa)
CST7cystatin-F. (145 aa)
LGALS9Galectin. (356 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
ZC3H8Zinc finger CCCH domain-containing protein 8 isoform X1. (308 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
TMEM131LTransmembrane protein 131-like isoform X1. (1608 aa)
FBXO7F-box only protein 7 isoform X1. (523 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
CD200OX-2 membrane glycoprotein. (267 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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