STRINGSTRING
NDFIP1 NDFIP1 SERPING1 SERPING1 SPINK5 SPINK5 EVPL EVPL CR2 CR2 LOC111184729 LOC111184729 FER FER UNC13D UNC13D IL5 IL5 LOC111182532 LOC111182532 CUNH17orf99 CUNH17orf99 MZB1 MZB1 KMT5B KMT5B FADD FADD PPP3CB PPP3CB CLCF1 CLCF1 HK1 HK1 MAPKAPK2 MAPKAPK2 C4BPB C4BPB TMEM248 TMEM248 IL27 IL27 SIRT1 SIRT1 CD74 CD74 CD81 CD81 LOC111182867 LOC111182867 TYROBP TYROBP LEP LEP SIGLEC10 SIGLEC10 ZP3 ZP3 FBXO38 FBXO38 ITGAM ITGAM FOXJ1 FOXJ1 SPHK2 SPHK2 TRPM4 TRPM4 CD177 CD177 RASGRP1 RASGRP1 SMAD7 SMAD7 TP53BP1 TP53BP1 IL13 IL13 CD226 CD226 LOC111180508 LOC111180508 PTPN22 PTPN22 CD59 CD59 PYCARD PYCARD TRAF6 TRAF6 MALT1 MALT1 EXOSC6 EXOSC6 THOC1 THOC1 PVR PVR NECTIN2 NECTIN2 KMT5C KMT5C IL4I1 IL4I1 FFAR3 FFAR3 TGFB1 TGFB1 DHX36 DHX36 NOD1 NOD1 GPI GPI TREM2 TREM2 AXL AXL GATA3 GATA3 CD37 CD37 IL20RB IL20RB DUSP10 DUSP10 TRIL TRIL RC3H2 RC3H2 PLCG2 PLCG2 FOXF1 FOXF1 LOC111177076 LOC111177076 FUT7 FUT7 IL17F IL17F LOC111176900 LOC111176900 AP1G1 AP1G1 SUSD4 SUSD4 LOC111176745 LOC111176745 LAG3 LAG3 TGFB3 TGFB3 CARD9 CARD9 LOC111178664 LOC111178664 LOC111178659 LOC111178659 HLX HLX IL17A IL17A SEMA7A SEMA7A PAXIP1 PAXIP1 TRAF2 TRAF2 TGFB2 TGFB2 KLRD1 KLRD1 MSH2 MSH2 PTPN6 PTPN6 DENND1B DENND1B IL12A IL12A LAMP1 LAMP1 DNASE1L3 DNASE1L3 PHB2 PHB2 LOC111176758 LOC111176758 CUNH12orf4 CUNH12orf4 IFNG IFNG LOC111175407 LOC111175407 ZC3H12A ZC3H12A LACC1 LACC1 IRAK3 IRAK3 CD96 CD96 TLR9 TLR9 WNT5A WNT5A SOCS5 SOCS5 ANXA1 ANXA1 PARP3 PARP3 APPL1 APPL1 TREX1 TREX1 SNX4 SNX4 RIF1 RIF1 TLR3 TLR3 NCKAP1L NCKAP1L CLNK CLNK STAT6 STAT6 CUEDC2 CUEDC2 LOC111171171 LOC111171171 ZBTB1 ZBTB1 TFRC TFRC GRN GRN BCL6 BCL6 CD28 CD28 LOC111169335 LOC111169335 RC3H1 RC3H1 FZD5 FZD5 HMCES HMCES LTA LTA AGER AGER NCR3 NCR3 VAMP7 VAMP7 IL12B IL12B SH2D1B SH2D1B SYK SYK LOC111168646 LOC111168646 CD40 CD40 FES FES FOXP3 FOXP3 HPX HPX LOXL3 LOXL3 CX3CR1 CX3CR1 VSIG4 VSIG4 KIT KIT WAS WAS LOC111169218 LOC111169218 PGLYRP2 PGLYRP2 FAM35A FAM35A DHX58 DHX58 HFE HFE SLAMF1 SLAMF1 COLEC11 COLEC11 ZBTB7B ZBTB7B PRAM1 PRAM1 CUNH1orf106 CUNH1orf106 PTPRC PTPRC SASH3 SASH3 SH2D1A SH2D1A CRTAM CRTAM ADORA2B ADORA2B CUNH20orf196 CUNH20orf196 NLRX1 NLRX1 TLR8 TLR8 TLR7 TLR7 IL18 IL18 CADM1 CADM1 LOC111167004 LOC111167004 LYN LYN CD84 CD84 STX7 STX7 APOA2 APOA2 IL27RA IL27RA APOA1 APOA1 ENPP3 ENPP3 LOC111166997 LOC111166997 SLAMF6 SLAMF6 VAMP8 VAMP8 DDX1 DDX1 ZPBP2 ZPBP2 PKN1 PKN1 PHB PHB LOC111166483 LOC111166483 TBX21 TBX21 RARA RARA LOC111166170 LOC111166170 LOC111165710 LOC111165710 NSD2 NSD2 MYB MYB VAV1 VAV1 ZNF683 ZNF683 ATG5 ATG5 CSMD3 CSMD3 COLEC10 COLEC10 FGL2 FGL2 NOD2 NOD2 MYD88 MYD88 FAM49B FAM49B MAP3K7 MAP3K7 UBE2J1 UBE2J1 XBP1 XBP1 EPHB2 EPHB2 EPX EPX F2RL1 F2RL1 PLA2G5 PLA2G5 FGR FGR FCN3 FCN3 CCL19 CCL19 BCR BCR PLA2G3 PLA2G3 LOC111184736 LOC111184736 LOC111184602 LOC111184602 IL10 IL10 BLK BLK C4BPA C4BPA CR1 CR1 DDX21 DDX21 INS INS LOC111184601 LOC111184601 AHR AHR IL1B IL1B TNF TNF Ob Ob SHB SHB EXOSC3 EXOSC3 ARID5A ARID5A IL1R1 IL1R1 IL18RAP IL18RAP LOC111186993 LOC111186993 APPL2 APPL2 PCK1 PCK1 ANKRD17 ANKRD17 PRKCZ PRKCZ IL21 IL21 MAD2L2 MAD2L2 PIK3R6 PIK3R6 TNFRSF1B TNFRSF1B ATAD5 ATAD5 IL7R IL7R TNFSF13 TNFSF13 IL18R1 IL18R1 S100B S100B DNASE1 DNASE1 PDPK1 PDPK1 LOC111186997 LOC111186997 P2RX7 P2RX7 GAB2 GAB2 C1QBP C1QBP ARRB2 ARRB2 SUPT6H SUPT6H NFKBIZ NFKBIZ LOC111184737 LOC111184737 CD55 CD55 RAC2 RAC2 LBP LBP TWIST1 TWIST1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NDFIP1NEDD4 family-interacting protein 1. (221 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (471 aa)
SPINK5Serine protease inhibitor Kazal-type 5. (841 aa)
EVPLEnvoplakin isoform X1. (2144 aa)
CR2Complement receptor type 2 isoform X1. (1471 aa)
LOC111184729Membrane cofactor protein-like isoform X1. (411 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
UNC13DProtein unc-13 homolog D isoform X1. (1121 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
LOC111182532Ankyrin repeat and KH domain-containing protein 1 isoform X1. (2642 aa)
CUNH17orf99Uncharacterized protein C17orf99 homolog. (199 aa)
MZB1Marginal zone B- and B1-cell-specific protein. (188 aa)
KMT5BHistone-lysine N-methyltransferase KMT5B isoform X1. (883 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CLCF1Cardiotrophin-like cytokine factor 1 isoform X1. (281 aa)
HK1Hexokinase-1 isoform X2. (935 aa)
MAPKAPK2LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (414 aa)
C4BPBC4b-binding protein beta chain isoform X1. (255 aa)
TMEM248Transmembrane protein 248 isoform X7. (971 aa)
IL27Interleukin-27 subunit alpha. (237 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (735 aa)
CD74HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa)
CD81Tetraspanin. (236 aa)
LOC111182867CMRF35-like molecule 8 isoform X1. (313 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
SIGLEC10Sialic acid-binding Ig-like lectin 10 isoform X1. (706 aa)
ZP3Zona pellucida sperm-binding protein 3. (421 aa)
FBXO38F-box only protein 38 isoform X1. (1200 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (872 aa)
FOXJ1Forkhead box protein J1. (422 aa)
SPHK2Sphingosine kinase 2 isoform X1. (655 aa)
TRPM4LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 4. (1204 aa)
CD177CD177 antigen isoform X1. (443 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (870 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
TP53BP1TP53-binding protein 1 isoform X1. (1976 aa)
IL13Interleukin-13. (131 aa)
CD226CD226 antigen. (335 aa)
LOC111180508Kallikrein-7-like; Belongs to the peptidase S1 family. (254 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa)
CD59CD59 glycoprotein. (123 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD. (195 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa)
EXOSC6Exosome complex component MTR3. (272 aa)
THOC1THO complex subunit 1. (657 aa)
PVRPoliovirus receptor isoform X1. (415 aa)
NECTIN2Nectin-2 isoform X1. (539 aa)
KMT5CHistone-lysine N-methyltransferase KMT5C isoform X1. (455 aa)
IL4I1L-amino-acid oxidase isoform X1. (653 aa)
FFAR3LOW QUALITY PROTEIN: free fatty acid receptor 3. (388 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
DHX36ATP-dependent RNA helicase DHX36 isoform X1. (1020 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (953 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
CD37Tetraspanin. (370 aa)
IL20RBInterleukin-20 receptor subunit beta isoform X1. (342 aa)
DUSP10Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
TRILTLR4 interactor with leucine rich repeats. (810 aa)
RC3H2Roquin-2. (1189 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
FOXF1Forkhead box protein F1. (375 aa)
LOC111177076Ficolin-2-like isoform X1. (326 aa)
FUT7Alpha-(1,3)-fucosyltransferase 7. (342 aa)
IL17Finterleukin-17F. (165 aa)
LOC111176900GTPase IMAP family member 5-like isoform X1. (332 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
SUSD4Sushi domain-containing protein 4 isoform X1. (488 aa)
LOC111176745Killer cell lectin-like receptor subfamily B member 1. (224 aa)
LAG3Lymphocyte activation gene 3 protein. (493 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
CARD9Caspase recruitment domain-containing protein 9 isoform X1. (539 aa)
LOC111178664HLA class II histocompatibility antigen, DM beta chain isoform X1. (263 aa)
LOC111178659Antigen peptide transporter 2-like isoform X4. (758 aa)
HLXH2.0-like homeobox protein. (488 aa)
IL17Ainterleukin-17A. (155 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
PAXIP1PAX-interacting protein 1 isoform X1. (1030 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
KLRD1Natural killer cells antigen CD94 isoform X1. (240 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
DENND1BDENN domain-containing protein 1B isoform X1. (776 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (411 aa)
DNASE1L3Deoxyribonuclease; Belongs to the DNase I family. (304 aa)
PHB2Prohibitin. (299 aa)
LOC111176758NKG2-A/NKG2-B type II integral membrane protein-like isoform X1. (256 aa)
CUNH12orf4Protein C12orf4 homolog isoform X1. (552 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
LOC111175407Amine oxidase. (524 aa)
ZC3H12AEndoribonuclease ZC3H12A. (583 aa)
LACC1Laccase domain-containing protein 1. (426 aa)
IRAK3Interleukin-1 receptor-associated kinase 3 isoform X2. (674 aa)
CD96LOW QUALITY PROTEIN: T-cell surface protein tactile. (546 aa)
TLR9LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
ANXA1Annexin. (346 aa)
PARP3Poly [ADP-ribose] polymerase. (586 aa)
APPL1DCC-interacting protein 13-alpha isoform X1. (708 aa)
TREX1Three-prime repair exonuclease 1. (314 aa)
SNX4Sorting nexin-4. (450 aa)
RIF1Telomere-associated protein RIF1 isoform X1. (2467 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
NCKAP1LNck-associated protein 1-like isoform X1. (1156 aa)
CLNKCytokine-dependent hematopoietic cell linker isoform X1. (452 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
CUEDC2CUE domain-containing protein 2 isoform X1. (284 aa)
LOC111171171Integrin alpha-M-like. (296 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1. (713 aa)
TFRCTransferrin receptor protein 1 isoform X1. (772 aa)
GRNGranulins isoform X1. (587 aa)
BCL6B-cell lymphoma 6 protein. (706 aa)
CD28T-cell-specific surface glycoprotein CD28. (265 aa)
LOC111169335Uncharacterized protein C20orf196 homolog. (46 aa)
RC3H1Roquin-1 isoform X1. (1135 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
HMCESAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (350 aa)
LTALymphotoxin-alpha; Belongs to the tumor necrosis factor family. (205 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (631 aa)
NCR3Natural cytotoxicity triggering receptor 3. (180 aa)
VAMP7Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa)
SH2D1BSH2 domain-containing protein 1B isoform X1. (138 aa)
SYKTyrosine-protein kinase. (626 aa)
LOC111168646CD59 glycoprotein-like. (123 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
FOXP3Forkhead box protein P3. (431 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (455 aa)
LOXL3Lysyl oxidase homolog 3 isoform X1. (772 aa)
CX3CR1CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
VSIG4V-set and immunoglobulin domain-containing protein 4. (399 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
LOC111169218Tripartite motif-containing protein 6-like. (487 aa)
PGLYRP2N-acetylmuramoyl-L-alanine amidase isoform X1. (581 aa)
FAM35AProtein FAM35A isoform X1. (905 aa)
DHX58Probable ATP-dependent RNA helicase DHX58 isoform X1. (680 aa)
HFEHereditary hemochromatosis protein isoform X1; Belongs to the MHC class I family. (356 aa)
SLAMF1Signaling lymphocytic activation molecule isoform X1. (378 aa)
COLEC11Collectin-11. (267 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B. (541 aa)
PRAM1PML-RARA-regulated adapter molecule 1 isoform X2. (541 aa)
CUNH1orf106Uncharacterized protein C1orf106 homolog. (540 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
CRTAMCytotoxic and regulatory T-cell molecule isoform X1. (391 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa)
CUNH20orf196Uncharacterized protein C20orf196 homolog isoform X1. (225 aa)
NLRX1NLR family member X1 isoform X1. (973 aa)
TLR8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1035 aa)
TLR7Toll-like receptor 7 isoform X1. (1086 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
CADM1Cell adhesion molecule 1 isoform X1. (469 aa)
LOC111167004LOW QUALITY PROTEIN: peptidoglycan recognition protein 3-like. (277 aa)
LYNTyrosine-protein kinase. (518 aa)
CD84SLAM family member 5 isoform X1. (341 aa)
STX7Syntaxin-7 isoform X1; Belongs to the syntaxin family. (261 aa)
APOA2Apolipoprotein A-II. (103 aa)
IL27RAInterleukin-27 receptor subunit alpha isoform X1. (656 aa)
APOA1Apolipoprotein A-I. (265 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (900 aa)
LOC111166997Fc receptor-like protein 3 isoform X2. (726 aa)
SLAMF6SLAM family member 6 isoform X1. (335 aa)
VAMP8Vesicle-associated membrane protein 8. (100 aa)
DDX1ATP-dependent RNA helicase DDX1. (740 aa)
ZPBP2Zona pellucida-binding protein 2 isoform X1. (326 aa)
PKN1Serine/threonine-protein kinase N1 isoform X1. (950 aa)
PHBProhibitin. (272 aa)
LOC111166483Signal transducer and activator of transcription. (787 aa)
TBX21T-box transcription factor TBX21. (535 aa)
RARARetinoic acid receptor alpha isoform X5. (584 aa)
LOC111166170C-type lectin domain family 4 member G-like isoform X1. (313 aa)
LOC111165710LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein; Belongs to the MHC class I family. (254 aa)
NSD2Histone-lysine N-methyltransferase NSD2 isoform X1. (1375 aa)
MYBTranscriptional activator Myb isoform X3. (761 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
ZNF683LOW QUALITY PROTEIN: tissue-resident T-cell transcription regulator protein ZNF683. (505 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CSMD3CUB and sushi domain-containing protein 3 isoform X5. (3707 aa)
COLEC10Collectin-10 isoform X1. (277 aa)
FGL2Fibroleukin. (440 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
FAM49BProtein FAM49B isoform X1. (324 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
UBE2J1Ubiquitin-conjugating enzyme E2 J1. (318 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (987 aa)
EPXEosinophil peroxidase. (715 aa)
F2RL1Proteinase-activated receptor 2. (315 aa)
PLA2G5Phospholipase A(2). (156 aa)
FGRTyrosine-protein kinase. (526 aa)
FCN3LOW QUALITY PROTEIN: ficolin-3. (270 aa)
CCL19C-C motif chemokine. (159 aa)
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
PLA2G3Group 3 secretory phospholipase A2 isoform X1. (516 aa)
LOC111184736Apolipoprotein R-like isoform X1. (189 aa)
LOC111184602Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (367 aa)
IL10Interleukin-10. (178 aa)
BLKTyrosine-protein kinase. (501 aa)
C4BPAC4b-binding protein alpha chain isoform X1. (616 aa)
CR1Complement receptor type 1 isoform X1. (1062 aa)
DDX21Nucleolar RNA helicase 2. (785 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LOC111184601Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (336 aa)
AHRAryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] (845 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
ObLeptin isoform X1. (167 aa)
SHBSH2 domain-containing adapter protein B. (507 aa)
EXOSC3Exosome complex component RRP40. (275 aa)
ARID5AAT-rich interactive domain-containing protein 5A isoform X1. (593 aa)
IL1R1Interleukin-1 receptor type 1 isoform X1. (686 aa)
IL18RAPInterleukin-18 receptor accessory protein isoform X1. (584 aa)
LOC111186993LOW QUALITY PROTEIN: solute carrier family 15 member 4-like. (615 aa)
APPL2DCC-interacting protein 13-beta isoform X2. (661 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (687 aa)
ANKRD17Ankyrin repeat domain-containing protein 17 isoform X1. (2618 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B. (454 aa)
ATAD5ATPase family AAA domain-containing protein 5 isoform X1. (1898 aa)
IL7RInterleukin-7 receptor subunit alpha isoform X1. (459 aa)
TNFSF13Tumor necrosis factor ligand superfamily member 13 isoform X1; Belongs to the tumor necrosis factor family. (247 aa)
IL18R1Interleukin-18 receptor 1 isoform X1. (539 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
DNASE1Deoxyribonuclease; Belongs to the DNase I family. (284 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
LOC111186997Solute carrier family 15 member 4-like. (90 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
C1QBPComplement component 1 Q subcomponent-binding protein, mitochondrial. (278 aa)
ARRB2Beta-arrestin-2 isoform X1. (409 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
NFKBIZNF-kappa-B inhibitor zeta. (726 aa)
LOC111184737Zona pellucida sperm-binding protein 3 receptor-like. (89 aa)
CD55Complement decay-accelerating factor isoform X1. (590 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X2. (192 aa)
LBPLipopolysaccharide-binding protein isoform X1. (537 aa)
TWIST1Twist-related protein 1. (205 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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