Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APCS | C1QC | A0A2Y9LZA8 | A0A2Y9LFX6 | LOW QUALITY PROTEIN: serum amyloid P-component. | Complement C1q subcomponent subunit C. | 0.413 |
| C1QC | APCS | A0A2Y9LFX6 | A0A2Y9LZA8 | Complement C1q subcomponent subunit C. | LOW QUALITY PROTEIN: serum amyloid P-component. | 0.413 |
| CASP10 | CASP8 | A0A2Y9MLF7 | A0A2Y9MQ94 | Caspase-10; Belongs to the peptidase C14A family. | Caspase-8; Belongs to the peptidase C14A family. | 0.974 |
| CASP10 | FADD | A0A2Y9MLF7 | A0A2Y9PNL8 | Caspase-10; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.995 |
| CASP10 | RIPK1 | A0A2Y9MLF7 | A0A2Y9PAG9 | Caspase-10; Belongs to the peptidase C14A family. | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. | 0.888 |
| CASP10 | TNF | A0A2Y9MLF7 | Q8WNR1 | Caspase-10; Belongs to the peptidase C14A family. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.717 |
| CASP10 | TRAF6 | A0A2Y9MLF7 | A0A2Y9PAB2 | Caspase-10; Belongs to the peptidase C14A family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.552 |
| CASP8 | CASP10 | A0A2Y9MQ94 | A0A2Y9MLF7 | Caspase-8; Belongs to the peptidase C14A family. | Caspase-10; Belongs to the peptidase C14A family. | 0.974 |
| CASP8 | CDK6 | A0A2Y9MQ94 | A0A2Y9P3B0 | Caspase-8; Belongs to the peptidase C14A family. | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | 0.482 |
| CASP8 | CTNNB1 | A0A2Y9MQ94 | A0A2Y9MAY9 | Caspase-8; Belongs to the peptidase C14A family. | Catenin beta-1. | 0.573 |
| CASP8 | FADD | A0A2Y9MQ94 | A0A2Y9PNL8 | Caspase-8; Belongs to the peptidase C14A family. | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. | 0.999 |
| CASP8 | IFNG | A0A2Y9MQ94 | A0A2Y9NDI2 | Caspase-8; Belongs to the peptidase C14A family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.509 |
| CASP8 | RIPK1 | A0A2Y9MQ94 | A0A2Y9PAG9 | Caspase-8; Belongs to the peptidase C14A family. | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. | 0.998 |
| CASP8 | TNF | A0A2Y9MQ94 | Q8WNR1 | Caspase-8; Belongs to the peptidase C14A family. | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] | 0.882 |
| CASP8 | TRAF6 | A0A2Y9MQ94 | A0A2Y9PAB2 | Caspase-8; Belongs to the peptidase C14A family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.815 |
| CDK6 | CASP8 | A0A2Y9P3B0 | A0A2Y9MQ94 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | Caspase-8; Belongs to the peptidase C14A family. | 0.482 |
| CDK6 | CTNNB1 | A0A2Y9P3B0 | A0A2Y9MAY9 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | Catenin beta-1. | 0.542 |
| CDK6 | MYC | A0A2Y9P3B0 | A0A2Y9LJB2 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. | 0.418 |
| CDK6 | NEDD9 | A0A2Y9P3B0 | A0A2Y9P8J4 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | Enhancer of filamentation 1 isoform X1. | 0.417 |
| CDK6 | RUNX1 | A0A2Y9P3B0 | A0A2Y9LIS3 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.741 |
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