STRINGSTRING
TNK1 TNK1 LOC111187417 LOC111187417 EFEMP1 EFEMP1 PTK2B PTK2B EGFR EGFR DSTYK DSTYK BLK BLK HCK HCK SRC SRC CSF1R CSF1R NDRG3 NDRG3 AATK AATK HMCN1 HMCN1 FER FER LOC111184310 LOC111184310 BAZ1B BAZ1B PDGFRB PDGFRB MAP2K6 MAP2K6 ITK ITK EPHB4 EPHB4 TESK1 TESK1 YES1 YES1 HIPK1 HIPK1 DYRK1B DYRK1B HIPK4 HIPK4 LTK LTK TYRO3 TYRO3 JAK1 JAK1 AXL AXL HIPK3 HIPK3 EPHB1 EPHB1 EPHB6 EPHB6 ABL1 ABL1 MET MET TTBK1 TTBK1 MUSK MUSK EPHA1 EPHA1 NRP1 NRP1 LOC111178990 LOC111178990 HIPK2 HIPK2 BTK BTK EPHA3 EPHA3 CSK CSK LCK LCK PEAK1 PEAK1 CLK3 CLK3 STYK1 STYK1 WEE2 WEE2 MST1R MST1R LOC111175797 LOC111175797 RPS6KA5 RPS6KA5 PDGFRL PDGFRL TIE1 TIE1 EPHA10 EPHA10 FLT1 FLT1 FLT3 FLT3 FGFR1 FGFR1 PKDCC PKDCC TWF1 TWF1 JAK2 JAK2 EPHA4 EPHA4 CLK1 CLK1 ERBB3 ERBB3 DYRK2 DYRK2 EPHB3 EPHB3 FLT4 FLT4 TNK2 TNK2 KDR KDR ERBB4 ERBB4 FGFR2 FGFR2 NRP2 NRP2 TXK TXK FGFR4 FGFR4 LOC111169208 LOC111169208 DDR1 DDR1 TEC TEC BMX BMX SYK SYK CLK4 CLK4 FES FES PDGFRA PDGFRA KIT KIT ROS1 ROS1 ROR2 ROR2 LOC111169254 LOC111169254 DDR2 DDR2 NTRK3 NTRK3 EPHA5 EPHA5 JAK3 JAK3 ERBB2 ERBB2 MATK MATK CLK2 CLK2 DCAF8 DCAF8 PTK2 PTK2 NTRK1 NTRK1 LYN LYN INSRR INSRR ABL2 ABL2 NTRK2 NTRK2 TYK2 TYK2 FGFR3 FGFR3 EPHA7 EPHA7 INSR INSR WEE1 WEE1 TEK TEK FGFRL1 FGFRL1 DYRK1A DYRK1A FRK FRK FYN FYN RET RET EPHB2 EPHB2 EPHA8 EPHA8 FGR FGR MERTK MERTK MELK MELK LOC111187154 LOC111187154 PTK6 PTK6 IGF1R IGF1R EPHA2 EPHA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNK1Non-receptor tyrosine-protein kinase TNK1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (699 aa)
LOC111187417Tyrosine-protein kinase. (612 aa)
EFEMP1EGF-containing fibulin-like extracellular matrix protein 1 isoform X1. (498 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
DSTYKDual serine/threonine and tyrosine protein kinase isoform X1. (929 aa)
BLKTyrosine-protein kinase. (501 aa)
HCKTyrosine-protein kinase. (506 aa)
SRCTyrosine-protein kinase. (562 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
NDRG3Protein NDRG3 isoform X1. (375 aa)
AATKSerine/threonine-protein kinase LMTK1 isoform X5. (1442 aa)
HMCN1Hemicentin-1. (5635 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
LOC111184310Tyrosine-protein kinase. (369 aa)
BAZ1BTyrosine-protein kinase BAZ1B. (1482 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (368 aa)
ITKTyrosine-protein kinase. (620 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
TESK1Dual specificity testis-specific protein kinase 1 isoform X1. (628 aa)
YES1Tyrosine-protein kinase. (541 aa)
HIPK1Homeodomain-interacting protein kinase 1 isoform X1. (1209 aa)
DYRK1BDual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1. (686 aa)
HIPK4Homeodomain-interacting protein kinase 4. (610 aa)
LTKLOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor. (922 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3 isoform X3. (896 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
HIPK3Homeodomain-interacting protein kinase 3 isoform X1. (1213 aa)
EPHB1Ephrin type-B receptor 1 isoform X1. (984 aa)
EPHB6Ephrin type-B receptor 6 isoform X1. (1010 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
METHepatocyte growth factor receptor isoform X1. (1382 aa)
TTBK1Tau-tubulin kinase 1 isoform X1. (1311 aa)
MUSKMuscle, skeletal receptor tyrosine-protein kinase isoform X1. (879 aa)
EPHA1Ephrin type-A receptor 1 isoform X1. (981 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
LOC111178990Ephrin type-A receptor 6 isoform X1. (774 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform X1. (1248 aa)
BTKTyrosine-protein kinase. (687 aa)
EPHA3Ephrin type-A receptor 3. (984 aa)
CSKTyrosine-protein kinase. (528 aa)
LCKTyrosine-protein kinase. (509 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1745 aa)
CLK3Dual specificity protein kinase CLK3 isoform X4. (566 aa)
STYK1Tyrosine-protein kinase STYK1 isoform X1. (427 aa)
WEE2Wee1-like protein kinase 2. (419 aa)
MST1RMacrophage-stimulating protein receptor isoform X1. (1406 aa)
LOC111175797Ephrin type-A receptor 6-like. (409 aa)
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
PDGFRLPlatelet-derived growth factor receptor-like protein isoform X2. (375 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
EPHA10Ephrin type-A receptor 10 isoform X1. (1017 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
FGFR1Fibroblast growth factor receptor. (823 aa)
PKDCCExtracellular tyrosine-protein kinase PKDCC isoform X1. (498 aa)
TWF1Twinfilin-1. (350 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
CLK1Dual specificity protein kinase CLK1 isoform X1; Belongs to the protein kinase superfamily. (485 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1338 aa)
DYRK2Dual specificity tyrosine-phosphorylation-regulated kinase 2. (601 aa)
EPHB3Ephrin type-B receptor 3. (997 aa)
FLT4Vascular endothelial growth factor receptor 3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1367 aa)
TNK2Activated CDC42 kinase 1 isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
FGFR2Fibroblast growth factor receptor. (841 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
TXKTyrosine-protein kinase. (550 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
LOC111169208Wee1-like protein kinase. (443 aa)
DDR1Tyrosine-protein kinase receptor. (917 aa)
TECTyrosine-protein kinase. (658 aa)
BMXTyrosine-protein kinase. (692 aa)
SYKTyrosine-protein kinase. (626 aa)
CLK4Dual specificity protein kinase CLK4 isoform X1; Belongs to the protein kinase superfamily. (481 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
ROS1Tyrosine-protein kinase receptor. (2348 aa)
ROR2Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (940 aa)
LOC111169254Discoidin domain-containing receptor 2-like. (323 aa)
DDR2Discoidin domain-containing receptor 2. (565 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
EPHA5Ephrin type-A receptor 5 isoform X1. (1037 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
MATKTyrosine-protein kinase. (706 aa)
CLK2Dual specificity protein kinase CLK2 isoform X1. (503 aa)
DCAF8DDB1- and CUL4-associated factor 8. (596 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
LYNTyrosine-protein kinase. (518 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
ABL2Tyrosine-protein kinase. (1174 aa)
NTRK2Tyrosine-protein kinase receptor. (822 aa)
TYK2Tyrosine-protein kinase. (1188 aa)
FGFR3Fibroblast growth factor receptor. (805 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (998 aa)
INSRTyrosine-protein kinase receptor. (1392 aa)
WEE1Wee1-like protein kinase. (646 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
FGFRL1Fibroblast growth factor receptor-like 1 isoform X1. (503 aa)
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1. (845 aa)
FRKTyrosine-protein kinase. (513 aa)
FYNTyrosine-protein kinase. (537 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1113 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (987 aa)
EPHA8Ephrin type-A receptor 8. (1005 aa)
FGRTyrosine-protein kinase. (526 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
MELKNon-specific serine/threonine protein kinase. (650 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
PTK6Non-specific protein-tyrosine kinase. (354 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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