11 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SH2B2	SH2B adapter protein 2 isoform X1. (703 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	SH2B1	SH2B adapter protein 1 isoform X1. (795 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	DOK2	Docking protein 2. (411 aa)
	FRS3	Fibroblast growth factor receptor substrate 3. (495 aa)
	TRADD	Tumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	SH2B3	SH2B adapter protein 3 isoform X1. (618 aa)
	GAB2	GRB2-associated-binding protein 2 isoform X1. (678 aa)
	LOC111186752	T-cell receptor-associated transmembrane adapter 1. (185 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DOK2	GRB2	A0A2Y9MA69	A0A2Y9PJ90	Docking protein 2.	Growth factor receptor-bound protein 2.	0.486
FRS2	FRS3	A0A2Y9MXU5	A0A2Y9P2Q5	Fibroblast growth factor receptor substrate 2.	Fibroblast growth factor receptor substrate 3.	0.437
FRS2	GRB2	A0A2Y9MXU5	A0A2Y9PJ90	Fibroblast growth factor receptor substrate 2.	Growth factor receptor-bound protein 2.	0.996
FRS2	PIK3R1	A0A2Y9MXU5	A0A2Y9Q8T5	Fibroblast growth factor receptor substrate 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.478
FRS3	FRS2	A0A2Y9P2Q5	A0A2Y9MXU5	Fibroblast growth factor receptor substrate 3.	Fibroblast growth factor receptor substrate 2.	0.437
FRS3	GRB2	A0A2Y9P2Q5	A0A2Y9PJ90	Fibroblast growth factor receptor substrate 3.	Growth factor receptor-bound protein 2.	0.791
FRS3	PIK3R1	A0A2Y9P2Q5	A0A2Y9Q8T5	Fibroblast growth factor receptor substrate 3.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.440
GAB2	GRB2	A0A2Y9Q2P6	A0A2Y9PJ90	GRB2-associated-binding protein 2 isoform X1.	Growth factor receptor-bound protein 2.	0.996
GAB2	PIK3R1	A0A2Y9Q2P6	A0A2Y9Q8T5	GRB2-associated-binding protein 2 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.973
GRB2	DOK2	A0A2Y9PJ90	A0A2Y9MA69	Growth factor receptor-bound protein 2.	Docking protein 2.	0.486
GRB2	FRS2	A0A2Y9PJ90	A0A2Y9MXU5	Growth factor receptor-bound protein 2.	Fibroblast growth factor receptor substrate 2.	0.996
GRB2	FRS3	A0A2Y9PJ90	A0A2Y9P2Q5	Growth factor receptor-bound protein 2.	Fibroblast growth factor receptor substrate 3.	0.791
GRB2	GAB2	A0A2Y9PJ90	A0A2Y9Q2P6	Growth factor receptor-bound protein 2.	GRB2-associated-binding protein 2 isoform X1.	0.996
GRB2	PIK3R1	A0A2Y9PJ90	A0A2Y9Q8T5	Growth factor receptor-bound protein 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.940
GRB2	SH2B1	A0A2Y9PJ90	A0A2Y9PDY3	Growth factor receptor-bound protein 2.	SH2B adapter protein 1 isoform X1.	0.972
GRB2	SH2B2	A0A2Y9PJ90	A0A2Y9PKA3	Growth factor receptor-bound protein 2.	SH2B adapter protein 2 isoform X1.	0.964
GRB2	SH2B3	A0A2Y9PJ90	A0A2Y9Q391	Growth factor receptor-bound protein 2.	SH2B adapter protein 3 isoform X1.	0.939
LOC111186752	PIK3R1	A0A2Y9Q2M7	A0A2Y9Q8T5	T-cell receptor-associated transmembrane adapter 1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.535
PIK3R1	FRS2	A0A2Y9Q8T5	A0A2Y9MXU5	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	Fibroblast growth factor receptor substrate 2.	0.478
PIK3R1	FRS3	A0A2Y9Q8T5	A0A2Y9P2Q5	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	Fibroblast growth factor receptor substrate 3.	0.440