STRINGSTRING
BRWD1 BRWD1 IRS4 IRS4 SHC1 SHC1 ENPP1 ENPP1 IRS1 IRS1 SORBS1 SORBS1 SNX4 SNX4 ELP6 ELP6 IRS2 IRS2 SNX1 SNX1 BRWD3 BRWD3 PHIP PHIP LOC111181964 LOC111181964 SNX2 SNX2 GRB10 GRB10 LMBRD1 LMBRD1 INS INS PIK3R1 PIK3R1 LOC111187339 LOC111187339 IGF1R IGF1R CCDC88A CCDC88A IGF1 IGF1 PTPN11 PTPN11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRWD1Bromodomain and WD repeat-containing protein 1 isoform X1. (2273 aa)
IRS4Insulin receptor substrate 4 isoform X1. (1267 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 isoform X1. (925 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
SORBS1Sorbin and SH3 domain-containing protein 1 isoform X30. (1291 aa)
SNX4Sorting nexin-4. (450 aa)
ELP6Elongator complex protein 6. (418 aa)
IRS2Insulin receptor substrate 2. (1347 aa)
SNX1Sorting nexin-1 isoform X1. (522 aa)
BRWD3Bromodomain and WD repeat-containing protein 3 isoform X1. (1800 aa)
PHIPPH-interacting protein isoform X2. (1650 aa)
LOC111181964Uncharacterized protein LOC111181964 isoform X1. (833 aa)
SNX2Sorting nexin-2. (519 aa)
GRB10Growth factor receptor-bound protein 10 isoform X1. (588 aa)
LMBRD1Probable lysosomal cobalamin transporter. (539 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC111187339LOW QUALITY PROTEIN: growth factor receptor-bound protein 10-like. (665 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
CCDC88AGirdin isoform X1. (2055 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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