STRINGSTRING
ASAP3 ASAP3 MAPK1 MAPK1 ACTN2 ACTN2 BCAR3 BCAR3 AJUBA AJUBA RHOU RHOU SLA SLA KLF11 KLF11 WASF1 WASF1 AFAP1 AFAP1 MTF2 MTF2 CPNE3 CPNE3 PARVA PARVA TEK TEK FERMT1 FERMT1 PEAK3 PEAK3 LOC111165064 LOC111165064 EFS EFS GRB7 GRB7 LASP1 LASP1 PIK3R2 PIK3R2 TLNRD1 TLNRD1 PTK2 PTK2 ADGRB1 ADGRB1 TADA1 TADA1 EZR EZR TLE2 TLE2 PTPRC PTPRC ARHGAP24 ARHGAP24 DCAF6 DCAF6 XIRP1 XIRP1 REXO2 REXO2 PRUNE1 PRUNE1 FES FES MSN MSN ACTB ACTB ITGA2B ITGA2B ATAT1 ATAT1 ILK ILK EPB41L5 EPB41L5 SHROOM4 SHROOM4 PDLIM7 PDLIM7 ITGB5 ITGB5 TNS1 TNS1 SORBS3 SORBS3 TM4SF20 TM4SF20 ITGAV ITGAV SH3KBP1 SH3KBP1 IQGAP1 IQGAP1 SORBS1 SORBS1 LPP LPP SYNE2 SYNE2 XIRP2 XIRP2 ACTN1 ACTN1 TNS2 TNS2 IRF2 IRF2 ITGB7 ITGB7 DLC1 DLC1 LMLN LMLN ITGB6 ITGB6 PGM5 PGM5 FERMT2 FERMT2 SENP1 SENP1 LIMD1 LIMD1 SORBS2 SORBS2 PRAG1 PRAG1 ZFYVE21 ZFYVE21 THSD1 THSD1 ITGBL1 ITGBL1 LIMA1 LIMA1 GSN GSN FOCAD FOCAD ITGA11 ITGA11 PEAK1 PEAK1 TNFSF13B TNFSF13B RSU1 RSU1 LCP1 LCP1 DST DST INPP5E INPP5E CORO2B CORO2B NRP1 NRP1 NEXN NEXN USP33 USP33 BCAR1 BCAR1 GFRAL GFRAL ZYX ZYX ITGB1 ITGB1 TES TES CAV1 CAV1 CAV2 CAV2 TLN2 TLN2 NPHS1 NPHS1 ARL14EP ARL14EP VASP VASP LOC111181189 LOC111181189 NEDD9 NEDD9 MAPRE2 MAPRE2 LIMK1 LIMK1 LOC111181196 LOC111181196 ITGB3 ITGB3 MAPK3 MAPK3 TGFB1I1 TGFB1I1 ARHGAP26 ARHGAP26 ACTG1 ACTG1 ANXA6 ANXA6 ITGB8 ITGB8 TRIP6 TRIP6 LIMS2 LIMS2 VCL VCL PPFIA1 PPFIA1 ACTN3 ACTN3 LOC111184310 LOC111184310 PTPRA PTPRA UBOX5 UBOX5 LPXN LPXN SRP68 SRP68 ITGB4 ITGB4 SRC SRC ARL14EPL ARL14EPL HCK HCK LOC111185338 LOC111185338 ARL2 ARL2 PAK1 PAK1 FLRT3 FLRT3 SLC6A4 SLC6A4 MAPRE1 MAPRE1 PALLD PALLD PARVB PARVB RALA RALA TNS3 TNS3 LOC111185769 LOC111185769 PARVG PARVG PTK2B PTK2B FBLIM1 FBLIM1 GIT1 GIT1 ATP6V0A2 ATP6V0A2 PHLDB2 PHLDB2 SYNPO2 SYNPO2 EPHA2 EPHA2 CASS4 CASS4 ITGA2 ITGA2 ITGA1 ITGA1 PXN PXN LOC111187154 LOC111187154 LIMS1 LIMS1 IL1RL1 IL1RL1 MYH9 MYH9 TLN1 TLN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASAP3arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1. (906 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
ACTN2Alpha-actinin-2. (894 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3 isoform X1. (832 aa)
AJUBALIM domain-containing protein ajuba isoform X1. (557 aa)
RHOURho-related GTP-binding protein RhoU. (255 aa)
SLASrc-like-adapter isoform X1. (276 aa)
KLF11Krueppel-like factor 11. (517 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
AFAP1Actin filament-associated protein 1 isoform X3. (820 aa)
MTF2Metal-response element-binding transcription factor 2 isoform X1. (593 aa)
CPNE3Copine-3. (533 aa)
PARVAAlpha-parvin isoform X1. (416 aa)
TEKAngiopoietin-1 receptor. (1125 aa)
FERMT1Fermitin family homolog 1. (677 aa)
PEAK3Uncharacterized protein. (436 aa)
LOC111165064Plectin isoform X1. (4685 aa)
EFSEmbryonal Fyn-associated substrate isoform X2. (561 aa)
GRB7Growth factor receptor-bound protein 7 isoform X1. (555 aa)
LASP1LIM and SH3 domain protein 1. (259 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
TLNRD1Mesoderm development candidate 1. (362 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
ADGRB1Brain-specific angiogenesis inhibitor 1 isoform X1. (888 aa)
TADA1Transcriptional adapter 1. (335 aa)
EZREzrin. (586 aa)
TLE2Transducin-like enhancer protein 2 isoform X1. (787 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa)
ARHGAP24Rho GTPase-activating protein 24 isoform X1. (748 aa)
DCAF6DDB1- and CUL4-associated factor 6 isoform X6. (939 aa)
XIRP1Xin actin-binding repeat-containing protein 1 isoform X4. (1120 aa)
REXO2Oligoribonuclease, mitochondrial. (237 aa)
PRUNE1Exopolyphosphatase PRUNE1 isoform X1. (453 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
MSNMoesin isoform X1. (579 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1034 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (447 aa)
ILKIntegrin-linked protein kinase. (452 aa)
EPB41L5Band 4.1-like protein 5 isoform X1. (726 aa)
SHROOM4Protein Shroom4 isoform X1. (1532 aa)
PDLIM7PDZ and LIM domain protein 7 isoform X1. (458 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
TNS1Tensin-1 isoform X1. (1914 aa)
SORBS3Vinexin isoform X3. (677 aa)
TM4SF20Transmembrane 4 L6 family member 20. (230 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1 isoform X1. (628 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
SORBS1Sorbin and SH3 domain-containing protein 1 isoform X30. (1291 aa)
LPPLipoma-preferred partner isoform X1. (615 aa)
SYNE2Nesprin-2 isoform X1. (6919 aa)
XIRP2Xin actin-binding repeat-containing protein 2 isoform X1. (3547 aa)
ACTN1Alpha-actinin-1 isoform X2. (914 aa)
TNS2Tensin-2 isoform X2. (1415 aa)
IRF2Interferon regulatory factor. (349 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (819 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1528 aa)
LMLNLeishmanolysin-like peptidase. (694 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
PGM5Phosphoglucomutase-like protein 5 isoform X1; Belongs to the phosphohexose mutase family. (567 aa)
FERMT2Fermitin family homolog 2 isoform X2. (691 aa)
SENP1Sentrin-specific protease 1 isoform X1. (690 aa)
LIMD1LIM domain-containing protein 1. (669 aa)
SORBS2Sorbin and SH3 domain-containing protein 2 isoform X1. (1515 aa)
PRAG1Tyrosine-protein kinase PRAG1 isoform X1. (1404 aa)
ZFYVE21Zinc finger FYVE domain-containing protein 21 isoform X2. (252 aa)
THSD1Thrombospondin type-1 domain-containing protein 1 isoform X1. (844 aa)
ITGBL1Integrin beta-like protein 1. (400 aa)
LIMA1LIM domain and actin-binding protein 1 isoform X1. (766 aa)
GSNGelsolin isoform X1. (770 aa)
FOCADFocadhesin isoform X1. (1804 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1745 aa)
TNFSF13BTumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (283 aa)
RSU1Ras suppressor protein 1 isoform X1. (277 aa)
LCP1Plastin-2. (627 aa)
DSTDystonin isoform X1. (7806 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (627 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (475 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
NEXNNexilin isoform X4. (673 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (910 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X4. (867 aa)
GFRALLOW QUALITY PROTEIN: GDNF family receptor alpha-like. (397 aa)
ZYXZyxin. (573 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
TESTestin isoform X1. (421 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
TLN2Talin-2 isoform X1. (2554 aa)
NPHS1Nephrin. (1270 aa)
ARL14EPARL14 effector protein. (260 aa)
VASPVasodilator-stimulated phosphoprotein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (384 aa)
LOC111181189Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6-like isoform X1. (300 aa)
NEDD9Enhancer of filamentation 1 isoform X1. (829 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2 isoform X1. (326 aa)
LIMK1LIM domain kinase 1 isoform X1. (647 aa)
LOC111181196Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6-like isoform X3. (261 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein isoform X1; Belongs to the paxillin family. (456 aa)
ARHGAP26Rho GTPase-activating protein 26 isoform X1. (815 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ANXA6Annexin. (673 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
TRIP6Thyroid receptor-interacting protein 6. (483 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (366 aa)
VCLVinculin isoform X2. (1134 aa)
PPFIA1Liprin-alpha-1 isoform X4. (1242 aa)
ACTN3Alpha-actinin-3 isoform X1. (902 aa)
LOC111184310Tyrosine-protein kinase. (369 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
UBOX5RING finger protein 37 isoform X1. (537 aa)
LPXNLeupaxin isoform X2; Belongs to the paxillin family. (387 aa)
SRP68Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (618 aa)
ITGB4Integrin beta. (1826 aa)
SRCTyrosine-protein kinase. (562 aa)
ARL14EPLARL14 effector protein-like. (152 aa)
HCKTyrosine-protein kinase. (506 aa)
LOC111185338Palladin-like. (653 aa)
ARL2ADP-ribosylation factor-like protein 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (268 aa)
PALLDPalladin isoform X1. (656 aa)
PARVBBeta-parvin isoform X1. (365 aa)
RALARas-related protein Ral-A. (206 aa)
TNS3Tensin-3 isoform X1. (1550 aa)
LOC111185769Arachidonate 15-lipoxygenase B-like. (677 aa)
PARVGGamma-parvin isoform X1. (331 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
FBLIM1Filamin-binding LIM protein 1. (374 aa)
GIT1ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (867 aa)
PHLDB2Pleckstrin homology-like domain family B member 2 isoform X1. (1364 aa)
SYNPO2Synaptopodin-2. (1261 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
CASS4Cas scaffolding protein family member 4 isoform X1. (821 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
PXNPaxillin isoform X2. (617 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (362 aa)
IL1RL1Interleukin-1 receptor-like 1 isoform X1. (592 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
TLN1Talin-1. (2541 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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