STRINGSTRING
XKR5 XKR5 TICAM2 TICAM2 XKR7 XKR7 NCF2 NCF2 NR1H3 NR1H3 UNC13D UNC13D MEGF10 MEGF10 PECAM1 PECAM1 CORO1A CORO1A CLN3 CLN3 ITGAL ITGAL HAVCR2 HAVCR2 THBS1 THBS1 ANXA11 ANXA11 SRPX SRPX ARHGAP25 ARHGAP25 AIF1 AIF1 VAMP7 VAMP7 TUB TUB ELANE ELANE Ob Ob MYH9 MYH9 MERTK MERTK LOC111187847 LOC111187847 ANXA3 ANXA3 ITGB2 ITGB2 LOC111186386 LOC111186386 SCARB1 SCARB1 XKR9 XKR9 LOC111186242 LOC111186242 P2RX7 P2RX7 CDC42SE1 CDC42SE1 RAB39A RAB39A SLC11A1 SLC11A1 RHOBTB2 RHOBTB2 ELMO2 ELMO2 ITGAV ITGAV GULP1 GULP1 RAB11FIP2 RAB11FIP2 ABCA7 ABCA7 RHOH RHOH LOC111170933 LOC111170933 PIK3CA PIK3CA FAM19A4 FAM19A4 PIKFYVE PIKFYVE TREX1 TREX1 ANXA1 ANXA1 BIN2 BIN2 PLD4 PLD4 TUSC2 TUSC2 MSR1 MSR1 RAB20 RAB20 LOC111176754 LOC111176754 MST1R MST1R GSN GSN GAS6 GAS6 MORN5 MORN5 ARHGAP12 ARHGAP12 LEPR LEPR LOC111177076 LOC111177076 ABL1 ABL1 IRF8 IRF8 LOC111170545 LOC111170545 CNN2 CNN2 ALOX15 ALOX15 MYO1G MYO1G CLCN3 CLCN3 RAC2 RAC2 TM9SF4 TM9SF4 TGM2 TGM2 RAB7B RAB7B XKR6 XKR6 ICAM5 ICAM5 ADGRB1 ADGRB1 RAB7A RAB7A LOC111167795 LOC111167795 MFGE8 MFGE8 CUNH1orf43 CUNH1orf43 BECN1 BECN1 PEAR1 PEAR1 LDLR LDLR RHOBTB1 RHOBTB1 RAB5A RAB5A RARA RARA DNM2 DNM2 TMEM175 TMEM175 ICAM3 ICAM3 VAV1 VAV1 XKR4 XKR4 BCR BCR CDC42 CDC42 FCN3 FCN3 PLA2G5 PLA2G5 XKR8 XKR8 CEBPE CEBPE NOD2 NOD2 MESD MESD MYD88 MYD88 TULP1 TULP1 AXL AXL TREM2 TREM2 COLEC12 COLEC12 ELMO1 ELMO1 SPG11 SPG11 TYRO3 TYRO3 ELMO3 ELMO3 EIF2AK1 EIF2AK1 ITGB3 ITGB3 RAC3 RAC3 JMJD6 JMJD6 TIMD4 TIMD4 LOC111182630 LOC111182630 LEP LEP TYROBP TYROBP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XKR5XK-related protein. (682 aa)
TICAM2TIR domain-containing adapter molecule 2. (235 aa)
XKR7XK-related protein. (580 aa)
NCF2Neutrophil cytosol factor 2 isoform X1. (526 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
UNC13DProtein unc-13 homolog D isoform X1. (1121 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1139 aa)
PECAM1Platelet endothelial cell adhesion molecule isoform X1. (701 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CLN3Battenin. (436 aa)
ITGALIntegrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa)
HAVCR2Hepatitis A virus cellular receptor 2 isoform X1. (375 aa)
THBS1Thrombospondin-1. (1170 aa)
ANXA11Annexin. (503 aa)
SRPXSushi repeat-containing protein SRPX isoform X1. (462 aa)
ARHGAP25Rho GTPase-activating protein 25 isoform X2. (643 aa)
AIF1Allograft inflammatory factor 1 isoform X1. (162 aa)
VAMP7Vesicle-associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
TUBTubby-like protein; Belongs to the TUB family. (511 aa)
ELANENeutrophil elastase; Belongs to the peptidase S1 family. (308 aa)
ObLeptin isoform X1. (167 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
LOC111187847Neutrophil cytosol factor 4 isoform X2. (339 aa)
ANXA3Annexin. (323 aa)
ITGB2Integrin beta. (769 aa)
LOC111186386Neutrophil cytosol factor 4-like. (250 aa)
SCARB1Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (511 aa)
XKR9XK-related protein. (373 aa)
LOC111186242SH3 domain-binding protein 1 isoform X1. (693 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CDC42SE1CDC42 small effector protein 1. (79 aa)
RAB39ARas-related protein Rab-39A isoform X1. (217 aa)
SLC11A1Natural resistance-associated macrophage protein 1 isoform X1. (546 aa)
RHOBTB2Rho-related BTB domain-containing protein 2 isoform X1. (755 aa)
ELMO2Engulfment and cell motility protein 2 isoform X1. (720 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
GULP1PTB domain-containing engulfment adapter protein 1 isoform X1. (381 aa)
RAB11FIP2Rab11 family-interacting protein 2 isoform X1. (516 aa)
ABCA7LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 7. (2103 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
LOC111170933Rho GTPase-activating protein 25-like isoform X1. (554 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FAM19A4Protein FAM19A4. (145 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2110 aa)
TREX1Three-prime repair exonuclease 1. (314 aa)
ANXA1Annexin. (346 aa)
BIN2Bridging integrator 2 isoform X1. (538 aa)
PLD4Phospholipase D4. (487 aa)
TUSC2Tumor suppressor candidate 2. (110 aa)
MSR1Macrophage scavenger receptor types I and II isoform X1. (454 aa)
RAB20Ras-related protein Rab-20. (235 aa)
LOC111176754C-type lectin domain family 7 member A-like isoform X1. (244 aa)
MST1RMacrophage-stimulating protein receptor isoform X1. (1406 aa)
GSNGelsolin isoform X1. (770 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
MORN5MORN repeat-containing protein 5 isoform X1. (172 aa)
ARHGAP12Rho GTPase-activating protein 12 isoform X1. (846 aa)
LEPRLeptin receptor isoform X1. (917 aa)
LOC111177076Ficolin-2-like isoform X1. (326 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
IRF8Interferon regulatory factor 8 isoform X1. (427 aa)
LOC111170545Rho-related GTP-binding protein RhoG. (191 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (380 aa)
ALOX15LOW QUALITY PROTEIN: arachidonate 15-lipoxygenase. (663 aa)
MYO1GUnconventional myosin-Ig isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
CLCN3Chloride channel protein. (866 aa)
RAC2Ras-related C3 botulinum toxin substrate 2 isoform X2. (192 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (642 aa)
TGM2Protein-glutamine gamma-glutamyltransferase 2. (687 aa)
RAB7BRas-related protein Rab-7b isoform X1. (210 aa)
XKR6XK-related protein. (631 aa)
ICAM5Intercellular adhesion molecule 5 isoform X1. (922 aa)
ADGRB1Brain-specific angiogenesis inhibitor 1 isoform X1. (888 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
LOC111167795Rho-related GTP-binding protein RhoG-like isoform X1. (230 aa)
MFGE8Lactadherin. (431 aa)
CUNH1orf43Uncharacterized protein C1orf43 homolog isoform X1. (253 aa)
BECN1Beclin-1 isoform X5. (471 aa)
PEAR1Platelet endothelial aggregation receptor 1 isoform X1. (1041 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
RHOBTB1Rho-related BTB domain-containing protein 1 isoform X1. (698 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
RARARetinoic acid receptor alpha isoform X5. (584 aa)
DNM2Dynamin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
TMEM175Endosomal/lysomomal potassium channel TMEM175 isoform X1. (507 aa)
ICAM3Intercellular adhesion molecule 3 isoform X1. (545 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
XKR4XK-related protein. (657 aa)
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
FCN3LOW QUALITY PROTEIN: ficolin-3. (270 aa)
PLA2G5Phospholipase A(2). (156 aa)
XKR8XK-related protein. (399 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
MESDLDLR chaperone MESD. (232 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (537 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
COLEC12Collectin-12. (742 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (727 aa)
SPG11Spatacsin isoform X1. (2443 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3 isoform X3. (896 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (782 aa)
EIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (623 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
RAC3Ras-related C3 botulinum toxin substrate 3 isoform X1. (192 aa)
JMJD6Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6. (414 aa)
TIMD4T-cell immunoglobulin and mucin domain-containing protein 4. (361 aa)
LOC111182630Platelet endothelial cell adhesion molecule-like isoform X2. (305 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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