STRINGSTRING
CD6 CD6 F2 F2 LBP LBP P2RX1 P2RX1 AP3B1 AP3B1 HMGB2 HMGB2 LOC111186286 LOC111186286 SERPINF2 SERPINF2 LOC111185731 LOC111185731 PTGS2 PTGS2 CHI3L1 CHI3L1 LOC111185785 LOC111185785 LOC111185794 LOC111185794 NFKBIZ NFKBIZ TRPV1 TRPV1 P2RX7 P2RX7 LOC111186281 LOC111186281 F2R F2R S100B S100B PDPN PDPN IL31RA IL31RA TRIM55 TRIM55 IL1A IL1A PPBP PPBP CXCL10 CXCL10 LOC111185888 LOC111185888 MS4A2 MS4A2 UNC13D UNC13D RELA RELA CD14 CD14 CUNH5orf30 CUNH5orf30 CCL24 CCL24 SCNN1B SCNN1B SCYL1 SCYL1 LAT LAT HK1 HK1 CNTF CNTF THBS1 THBS1 TAC1 TAC1 SPHK1 SPHK1 TYROBP TYROBP NKG7 NKG7 HAMP HAMP IL4R IL4R FASN FASN RASGRP1 RASGRP1 SNAP23 SNAP23 IL13 IL13 CCL26 CCL26 EIF2AK1 EIF2AK1 CSF1 CSF1 PNMA8A PNMA8A NLRP9 NLRP9 HRH4 HRH4 NOTCH2 NOTCH2 NUPR1 NUPR1 PYCARD PYCARD LOC111181112 LOC111181112 BMPR1B BMPR1B PTGIR PTGIR LOC111179563 LOC111179563 GPR32 GPR32 PLD3 PLD3 BMP6 BMP6 TGFB1 TGFB1 C5AR2 C5AR2 C5AR1 C5AR1 NFKBIB NFKBIB TREM2 TREM2 CSRP3 CSRP3 AXL AXL IL34 IL34 LOC111177582 LOC111177582 IL20RB IL20RB EPHB6 EPHB6 ITGB1 ITGB1 TSPAN2 TSPAN2 RAB44 RAB44 CHIA CHIA NOTCH1 NOTCH1 FUT7 FUT7 IL17F IL17F LOC111176755 LOC111176755 TNFRSF1B TNFRSF1B NR1H4 NR1H4 EPHA2 EPHA2 TNFRSF4 TNFRSF4 MTOR MTOR LOC111187428 LOC111187428 IL36G IL36G IL1RN IL1RN IL36RN IL36RN REL REL LOC111187580 LOC111187580 CXCL11 CXCL11 SMAD1 SMAD1 CMKLR1 CMKLR1 PARK7 PARK7 PTGER4 PTGER4 LOC111187154 LOC111187154 CTNNBIP1 CTNNBIP1 STARD7 STARD7 CXCL13 CXCL13 LOC111187648 LOC111187648 CXCL9 CXCL9 TLR2 TLR2 HMOX1 HMOX1 TNF TNF IL1B IL1B IL6 IL6 LOC111179403 LOC111179403 TNFRSF1A TNFRSF1A PSEN1 PSEN1 LOC111178219 LOC111178219 IL17A IL17A SMO SMO C3AR1 C3AR1 C5 C5 ALOX5AP ALOX5AP HMGB1 HMGB1 PTN PTN TLR4 TLR4 LOC111176714 LOC111176714 LOC111177583 LOC111177583 TLR5 TLR5 APP APP RARRES2 RARRES2 CCR2 CCR2 LOC111177292 LOC111177292 PTGS1 PTGS1 PNMA1 PNMA1 ANO6 ANO6 LOC111176754 LOC111176754 IFNG IFNG POLB POLB IDO1 IDO1 CXCR6 CXCR6 HYAL3 HYAL3 TUSC2 TUSC2 JUN JUN PTGER2 PTGER2 NFE2L2 NFE2L2 AHSG AHSG LOC111175557 LOC111175557 LOC111174480 LOC111174480 CD96 CD96 HYAL1 HYAL1 UCN UCN TLR9 TLR9 ITIH4 ITIH4 IL17D IL17D IL5RA IL5RA NLRC4 NLRC4 CCRL2 CCRL2 ADAM8 ADAM8 ANXA1 ANXA1 CCR1 CCR1 CCR3 CCR3 KNG1 KNG1 TREX1 TREX1 PXK PXK SCN9A SCN9A LOC111171817 LOC111171817 FN1 FN1 TLR3 TLR3 LOC111171209 LOC111171209 AFAP1L2 AFAP1L2 HIF1A HIF1A STK39 STK39 MFHAS1 MFHAS1 LIPA LIPA LOC111170450 LOC111170450 PTGDR PTGDR NRROS NRROS ALOX5 ALOX5 TLR6 TLR6 CUL3 CUL3 TOLLIP TOLLIP TNFSF4 TNFSF4 CCL20 CCL20 SLC11A1 SLC11A1 IRAK2 IRAK2 ELF3 ELF3 XK XK AGER AGER NLRP6 NLRP6 AIF1 AIF1 FUT4 FUT4 LOC111170700 LOC111170700 TLR10 TLR10 TLR1 TLR1 ELANE ELANE IL17RC IL17RC LIAS LIAS C2CD4C C2CD4C AZU1 AZU1 SYK SYK SIGIRR SIGIRR F12 F12 CD40 CD40 IL17RE IL17RE FOXP3 FOXP3 ODAM ODAM GPER1 GPER1 ECM1 ECM1 SLAMF8 SLAMF8 LOXL3 LOXL3 AGTR2 AGTR2 CX3CR1 CX3CR1 KIT KIT MAP2K3 MAP2K3 PLP1 PLP1 DHRS7B DHRS7B PTGER1 PTGER1 SELP SELP ASH1L ASH1L S100A12 S100A12 SLAMF1 SLAMF1 TBXA2R TBXA2R LOC111167902 LOC111167902 TIMP1 TIMP1 CCR6 CCR6 CXCR3 CXCR3 S1PR3 S1PR3 LOC111167106 LOC111167106 LOC111167555 LOC111167555 SCYL3 SCYL3 ACKR1 ACKR1 TLR8 TLR8 TLR7 TLR7 IL18 IL18 XCL1 XCL1 C3 C3 PBXIP1 PBXIP1 S100A8 S100A8 BMP2 BMP2 NKIRAS2 NKIRAS2 WDR83 WDR83 CCL17 CCL17 STAT3 STAT3 CCR7 CCR7 LTB4R LTB4R LOC111166100 LOC111166100 VNN1 VNN1 EXT1 EXT1 ACKR2 ACKR2 CX3CL1 CX3CL1 GPR33 GPR33 CCL22 CCL22 TIRAP TIRAP CRHBP CRHBP MYLK3 MYLK3 LOC111163733 LOC111163733 LOC111163729 LOC111163729 CCL5 CCL5 CIITA CIITA TRAF3IP2 TRAF3IP2 CD40LG CD40LG ADCY8 ADCY8 MYD88 MYD88 CCR4 CCR4 GGT5 GGT5 LOC111163732 LOC111163732 F3 F3 LOC111163731 LOC111163731 PLAA PLAA CCL21 CCL21 PLA2G10 PLA2G10 F2RL1 F2RL1 UMOD UMOD PTAFR PTAFR C1QA C1QA B4GALT1 B4GALT1 CCL19 CCL19 MIF MIF PLA2G3 PLA2G3 IL17B IL17B ACER3 ACER3 ADCY1 ADCY1 INS INS DHX9 DHX9 TICAM2 TICAM2 TCIRG1 TCIRG1 MAPKAPK2 MAPKAPK2 PRCP PRCP PJA2 PJA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD6T-cell differentiation antigen CD6 isoform X1. (675 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
LBPLipopolysaccharide-binding protein isoform X1. (537 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa)
HMGB2High mobility group protein B2. (210 aa)
LOC111186286Chondroadherin-like protein isoform X1. (807 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (558 aa)
LOC111185731C-C motif chemokine. (99 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
CHI3L1LOW QUALITY PROTEIN: chitinase-3-like protein 1; Belongs to the glycosyl hydrolase 18 family. (393 aa)
LOC111185785Baculoviral IAP repeat-containing protein 1 isoform X1. (1759 aa)
LOC111185794C-C motif chemokine. (97 aa)
NFKBIZNF-kappa-B inhibitor zeta. (726 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (864 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
LOC111186281Chondroadherin-like protein isoform X1. (807 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
PDPNPodoplanin isoform X1. (235 aa)
IL31RALOW QUALITY PROTEIN: interleukin-31 receptor subunit alpha. (520 aa)
TRIM55Tripartite motif-containing protein 55 isoform X1. (534 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
PPBPC-X-C motif chemokine. (119 aa)
CXCL10C-X-C motif chemokine. (103 aa)
LOC111185888C-C motif chemokine. (99 aa)
MS4A2High affinity immunoglobulin epsilon receptor subunit beta. (243 aa)
UNC13DProtein unc-13 homolog D isoform X1. (1121 aa)
RELATranscription factor p65 isoform X1. (562 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa)
CUNH5orf30UNC119-binding protein C5orf30 homolog isoform X1. (207 aa)
CCL24C-C motif chemokine 24. (119 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
SCYL1N-terminal kinase-like protein isoform X1. (807 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (270 aa)
HK1Hexokinase-1 isoform X2. (935 aa)
CNTFCiliary neurotrophic factor. (200 aa)
THBS1Thrombospondin-1. (1170 aa)
TAC1Protachykinin-1 isoform X1. (130 aa)
SPHK1Sphingosine kinase 1 isoform X2. (484 aa)
TYROBPTYRO protein tyrosine kinase-binding protein isoform X1. (126 aa)
NKG7Protein NKG7. (165 aa)
HAMPHepcidin isoform X2. (108 aa)
IL4RInterleukin-4 receptor subunit alpha isoform X1. (831 aa)
FASNFatty acid synthase isoform X1. (2680 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (870 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
IL13Interleukin-13. (131 aa)
CCL26C-C motif chemokine 26. (94 aa)
EIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (623 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
PNMA8ALOW QUALITY PROTEIN: paraneoplastic antigen-like protein 8A. (481 aa)
NLRP9NACHT, LRR and PYD domains-containing protein 9. (989 aa)
HRH4Histamine H4 receptor. (336 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
NUPR1Nuclear protein 1. (82 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD. (195 aa)
LOC111181112Uncharacterized protein LOC111181112. (257 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
LOC111179563Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. (345 aa)
GPR32LOW QUALITY PROTEIN: probable G-protein coupled receptor 32. (313 aa)
PLD3Phospholipase D3. (490 aa)
BMP6Bone morphogenetic protein 6. (496 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2 isoform X1. (343 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
NFKBIBNF-kappa-B inhibitor beta. (353 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
CSRP3Cysteine and glycine-rich protein 3 isoform X2. (194 aa)
AXLLOW QUALITY PROTEIN: tyrosine-protein kinase receptor UFO. (887 aa)
IL34Interleukin-34. (235 aa)
LOC111177582C2 calcium-dependent domain-containing protein 4A-like. (368 aa)
IL20RBInterleukin-20 receptor subunit beta isoform X1. (342 aa)
EPHB6Ephrin type-B receptor 6 isoform X1. (1010 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
TSPAN2Tetraspanin. (221 aa)
RAB44Ras-related protein Rab-44 isoform X1. (1086 aa)
CHIAAcidic mammalian chitinase isoform X1; Belongs to the glycosyl hydrolase 18 family. (474 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
FUT7Alpha-(1,3)-fucosyltransferase 7. (342 aa)
IL17Finterleukin-17F. (165 aa)
LOC111176755Oxidized low-density lipoprotein receptor 1-like isoform X1. (273 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B. (454 aa)
NR1H4Bile acid receptor isoform X1. (486 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
TNFRSF4Tumor necrosis factor receptor superfamily member 4. (278 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
LOC111187428Interleukin-1. (118 aa)
IL36GInterleukin-1. (266 aa)
IL1RNInterleukin-1. (177 aa)
IL36RNInterleukin-1. (155 aa)
RELProto-oncogene c-Rel. (594 aa)
LOC111187580C-X-C motif chemokine. (112 aa)
CXCL11C-X-C motif chemokine 11. (100 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
CMKLR1Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
PARK7Protein DJ-1. (189 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (486 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (81 aa)
STARD7stAR-related lipid transfer protein 7, mitochondrial. (382 aa)
CXCL13C-X-C motif chemokine 13. (109 aa)
LOC111187648C-X-C motif chemokine 6-like. (113 aa)
CXCL9C-X-C motif chemokine. (160 aa)
TLR2Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa)
LOC111179403Cytochrome b-245 light chain isoform X1. (202 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (445 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
LOC111178219LOW QUALITY PROTEIN: toll-like receptor 13. (661 aa)
IL17Ainterleukin-17A. (155 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
C3AR1C3a anaphylatoxin chemotactic receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (498 aa)
C5Complement C5 isoform X1. (1677 aa)
ALOX5APArachidonate 5-lipoxygenase-activating protein. (161 aa)
HMGB1High mobility group protein B1. (215 aa)
PTNPleiotrophin isoform X1. (168 aa)
TLR4Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa)
LOC111176714Scavenger receptor cysteine-rich type 1 protein M130 isoform X1. (1115 aa)
LOC111177583C2 calcium-dependent domain-containing protein 4A-like. (370 aa)
TLR5Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
RARRES2Retinoic acid receptor responder protein 2. (166 aa)
CCR2C-C chemokine receptor type 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
LOC111177292Alpha-1-acid glycoprotein-like isoform X1. (218 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (600 aa)
PNMA1Paraneoplastic antigen Ma1. (352 aa)
ANO6Anoctamin. (951 aa)
LOC111176754C-type lectin domain family 7 member A-like isoform X1. (244 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
IDO1Indoleamine 2,3-dioxygenase 1 isoform X1. (410 aa)
CXCR6C-X-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (341 aa)
HYAL3Hyaluronidase. (415 aa)
TUSC2Tumor suppressor candidate 2. (110 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (343 aa)
PTGER2Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (354 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (622 aa)
AHSGalpha-2-HS-glycoprotein. (360 aa)
LOC111175557Somatostatin receptor type 2-like. (266 aa)
LOC111174480C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
CD96LOW QUALITY PROTEIN: T-cell surface protein tactile. (546 aa)
HYAL1Hyaluronidase. (448 aa)
UCNUrocortin. (126 aa)
TLR9LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain H4 isoform X1. (999 aa)
IL17Dinterleukin-17D. (309 aa)
IL5RAInterleukin-5 receptor subunit alpha isoform X1. (417 aa)
NLRC4NLR family CARD domain-containing protein 4 isoform X1. (1024 aa)
CCRL2C-C chemokine receptor-like 2 isoform X2; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa)
ANXA1Annexin. (346 aa)
CCR1C-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
CCR3C-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
KNG1Kininogen-1 isoform X1. (627 aa)
TREX1Three-prime repair exonuclease 1. (314 aa)
PXKPX domain-containing protein kinase-like protein isoform X9. (583 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
LOC111171817C-X-C chemokine receptor type 2-like; Belongs to the G-protein coupled receptor 1 family. (368 aa)
FN1Fibronectin isoform X5. (2478 aa)
TLR3Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
LOC111171209C-C motif chemokine 13-like. (116 aa)
AFAP1L2Actin filament-associated protein 1-like 2 isoform X1. (938 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase isoform X1. (539 aa)
MFHAS1Malignant fibrous histiocytoma-amplified sequence 1 isoform X1. (1058 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
LOC111170450Cytochrome b-245 heavy chain isoform X1. (570 aa)
PTGDRProstaglandin D2 receptor. (361 aa)
NRROSNegative regulator of reactive oxygen species isoform X1. (699 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
TLR6Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (768 aa)
TOLLIPToll-interacting protein isoform X1. (273 aa)
TNFSF4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa)
CCL20C-C motif chemokine. (97 aa)
SLC11A1Natural resistance-associated macrophage protein 1 isoform X1. (546 aa)
IRAK2LOW QUALITY PROTEIN: interleukin-1 receptor-associated kinase-like 2. (621 aa)
ELF3ETS-related transcription factor Elf-3. (372 aa)
XKXK-related protein. (444 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (631 aa)
NLRP6LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 6. (876 aa)
AIF1Allograft inflammatory factor 1 isoform X1. (162 aa)
FUT4Alpha-(1,3)-fucosyltransferase 4. (458 aa)
LOC111170700Complement C4-like isoform X1. (1740 aa)
TLR10Toll-like receptor 10; Belongs to the Toll-like receptor family. (817 aa)
TLR1Toll-like receptor 1; Belongs to the Toll-like receptor family. (796 aa)
ELANENeutrophil elastase; Belongs to the peptidase S1 family. (308 aa)
IL17RCInterleukin-17 receptor C isoform X1. (713 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
C2CD4CC2 calcium-dependent domain-containing protein 4C. (420 aa)
AZU1Azurocidin. (252 aa)
SYKTyrosine-protein kinase. (626 aa)
SIGIRRSingle Ig IL-1-related receptor isoform X1. (479 aa)
F12LOW QUALITY PROTEIN: coagulation factor XII. (650 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa)
IL17REInterleukin-17 receptor E. (667 aa)
FOXP3Forkhead box protein P3. (431 aa)
ODAMLOW QUALITY PROTEIN: odontogenic ameloblast-associated protein. (281 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ECM1Extracellular matrix protein 1 isoform X1. (544 aa)
SLAMF8SLAM family member 8 isoform X1. (318 aa)
LOXL3Lysyl oxidase homolog 3 isoform X1. (772 aa)
AGTR2Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (362 aa)
CX3CR1CX3C chemokine receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (475 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
PLP1Myelin proteolipid protein isoform X1. (277 aa)
DHRS7BDehydrogenase/reductase SDR family member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
PTGER1Prostaglandin E2 receptor EP1 subtype. (405 aa)
SELPP-selectin isoform X1. (768 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L isoform X1. (2964 aa)
S100A12LOW QUALITY PROTEIN: protein S100-A12; Belongs to the S-100 family. (136 aa)
SLAMF1Signaling lymphocytic activation molecule isoform X1. (378 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
LOC111167902Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
TIMP1Metalloproteinase inhibitor 1. (257 aa)
CCR6C-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
CXCR3C-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (366 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC111167106Protein S100-A9-like; Belongs to the S-100 family. (135 aa)
LOC111167555Caspase-13 isoform X1; Belongs to the peptidase C14A family. (377 aa)
SCYL3Protein-associating with the carboxyl-terminal domain of ezrin isoform X1. (742 aa)
ACKR1Atypical chemokine receptor 1 isoform X1. (518 aa)
TLR8Toll-like receptor 8; Belongs to the Toll-like receptor family. (1035 aa)
TLR7Toll-like receptor 7 isoform X1. (1086 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
XCL1Lymphotactin. (111 aa)
C3Complement C3 isoform X1. (1695 aa)
PBXIP1pre-B-cell leukemia transcription factor-interacting protein 1 isoform X1. (731 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1. (191 aa)
WDR83WD repeat domain-containing protein 83. (315 aa)
CCL17C-C motif chemokine. (109 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CCR7C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
LTB4RLOW QUALITY PROTEIN: leukotriene B4 receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
LOC111166100Complement C3-like isoform X1. (1706 aa)
VNN1Pantetheinase. (514 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
ACKR2Atypical chemokine receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CX3CL1Fractalkine. (469 aa)
GPR33Probable G-protein coupled receptor 33. (340 aa)
CCL22C-C motif chemokine. (93 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein. (226 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
LOC111163733C-C motif chemokine. (90 aa)
LOC111163729C-C motif chemokine. (194 aa)
CCL5C-C motif chemokine. (91 aa)
CIITAMHC class II transactivator isoform X2. (1206 aa)
TRAF3IP2Adapter protein CIKS isoform X1. (564 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
CCR4C-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (359 aa)
GGT5Gamma-glutamyltransferase 5 isoform X1. (713 aa)
LOC111163732C-C motif chemokine. (92 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (292 aa)
LOC111163731C-C motif chemokine. (93 aa)
PLAAPhospholipase A-2-activating protein. (796 aa)
CCL21C-C motif chemokine 21 isoform X1. (131 aa)
PLA2G10Phospholipase A(2). (159 aa)
F2RL1Proteinase-activated receptor 2. (315 aa)
UMODUromodulin. (643 aa)
PTAFRPlatelet-activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
C1QAComplement C1q subcomponent subunit A. (245 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (402 aa)
CCL19C-C motif chemokine. (159 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
PLA2G3Group 3 secretory phospholipase A2 isoform X1. (516 aa)
IL17Binterleukin-17B isoform X1. (214 aa)
ACER3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (267 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
DHX9ATP-dependent RNA helicase A isoform X1. (1253 aa)
TICAM2TIR domain-containing adapter molecule 2. (235 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa)
MAPKAPK2LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (414 aa)
PRCPLysosomal Pro-X carboxypeptidase. (499 aa)
PJA2E3 ubiquitin-protein ligase Praja-2. (709 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (28%) [HD]