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| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | ERCC3 | TFIIH basal transcription factor complex helicase XPB subunit isoform X1. (782 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | CUNH11orf80 | Type 2 DNA topoisomerase 6 subunit B-like isoform X1. (567 aa) |
| | BPTF | Nucleosome-remodeling factor subunit BPTF isoform X1. (2871 aa) |
| | SUPV3L1 | ATP-dependent RNA helicase SUPV3L1, mitochondrial. (787 aa) |
| | G3BP1 | Ras GTPase-activating protein-binding protein 1 isoform X2. (504 aa) |
| | RAD50 | DNA repair protein RAD50 isoform X1. (1344 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | PMS2 | Mismatch repair endonuclease PMS2 isoform X4. (894 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2590 aa) |
| | INO80 | DNA helicase INO80 isoform X1. (1563 aa) |
| | SRCAP | Helicase SRCAP isoform X1. (3238 aa) |
| | WRNIP1 | ATPase WRNIP1 isoform X1. (638 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | TTF2 | Transcription termination factor 2 isoform X1. (1171 aa) |
| | CHD1L | chromodomain-helicase-DNA-binding protein 1-like isoform X1. (898 aa) |
| | NAV2 | Neuron navigator 2 isoform X4. (2486 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | SMARCAD1 | annotation not available (1028 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | DHX36 | ATP-dependent RNA helicase DHX36 isoform X1. (1020 aa) |
| | HLTF | Helicase-like transcription factor isoform X1. (1008 aa) |
| | ATRX | Transcriptional regulator ATRX isoform X1. (2510 aa) |
| | ERCC2 | TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (823 aa) |
| | LOC111179605 | LOW QUALITY PROTEIN: ras GTPase-activating protein-binding protein 1-like. (470 aa) |
| | RAD54B | DNA repair and recombination protein RAD54B isoform X1. (909 aa) |
| | CEP41 | Centrosomal protein of 41 kDa isoform X1. (374 aa) |
| | FBXO18 | F-box DNA helicase 1. (1040 aa) |
| | LOC111176590 | Cat eye syndrome critical region protein 2 isoform X1. (1437 aa) |
| | XRCC2 | DNA repair protein XRCC2. (280 aa) |
| | MSH4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (986 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (670 aa) |
| | XRCC3 | DNA repair protein XRCC3. (396 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | DDX11 | ATP-dependent DNA helicase DDX11 isoform X1. (905 aa) |
| | RAD54L | DNA repair and recombination protein RAD54-like isoform X1. (756 aa) |
| | MLH3 | DNA mismatch repair protein Mlh3 isoform X1. (1455 aa) |
| | RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa) |
| | CHD4 | chromodomain-helicase-DNA-binding protein 4 isoform X1. (1940 aa) |
| | HELB | DNA helicase B isoform X1. (1079 aa) |
| | RBBP4 | Histone-binding protein RBBP4. (425 aa) |
| | GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | ZRANB3 | DNA annealing helicase and endonuclease ZRANB3 isoform X1. (1077 aa) |
| | RAD54L2 | Helicase ARIP4 isoform X1. (1465 aa) |
| | WRN | Werner syndrome ATP-dependent helicase isoform X1. (1454 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) |
| | SMARCA2 | Probable global transcription activator SNF2L2 isoform X1. (1597 aa) |
| | SMC5 | Structural maintenance of chromosomes protein 5 isoform X1. (1106 aa) |
| | SMARCAL1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (951 aa) |
| | FANCM | Fanconi anemia group M protein isoform X1. (2057 aa) |
| | TM4SF19 | Transmembrane 4 L6 family member 19. (202 aa) |
| | RFC1 | Replication factor C subunit 1. (1146 aa) |
| | PMS1 | PMS1 protein homolog 1 isoform X1. (932 aa) |
| | RAD51B | DNA repair protein RAD51 homolog 2. (350 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5. (733 aa) |
| | TWNK | Twinkle protein, mitochondrial isoform X1. (684 aa) |
| | KIAA1257 | Uncharacterized protein KIAA1257 homolog isoform X2. (1085 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | ERCC6L | DNA excision repair protein ERCC-6-like. (1249 aa) |
| | RAD51D | DNA repair protein RAD51 homolog 4 isoform X1. (328 aa) |
| | ERCC6 | DNA excision repair protein ERCC-6. (1485 aa) |
| | SMARCA1 | Probable global transcription activator SNF2L1 isoform X1. (1070 aa) |
| | POLQ | DNA polymerase theta isoform X1. (2608 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1. (1097 aa) |
| | IGHMBP2 | DNA-binding protein SMUBP-2 isoform X1. (982 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (990 aa) |
| | DHX9 | ATP-dependent RNA helicase A isoform X1. (1253 aa) |
| | MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1129 aa) |
| | RSF1 | Remodeling and spacing factor 1 isoform X1. (1436 aa) |
| | CHD1 | chromodomain-helicase-DNA-binding protein 1 isoform X1. (1798 aa) |
| | CHD6 | chromodomain-helicase-DNA-binding protein 6. (2720 aa) |
| | CDK7 | Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | CHD7 | chromodomain-helicase-DNA-binding protein 7 isoform X1. (3050 aa) |
| | RAD17 | Cell cycle checkpoint protein RAD17 isoform X1. (739 aa) |
| | MPHOSPH9 | M-phase phosphoprotein 9 isoform X1. (1180 aa) |
| | CHTF18 | Chromosome transmission fidelity protein 18 homolog. (1006 aa) |
| | XRCC6 | X-ray repair cross-complementing protein 6. (609 aa) |
| | CHD2 | chromodomain-helicase-DNA-binding protein 2 isoform X1. (1862 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1355 aa) |
| | CHD3 | chromodomain-helicase-DNA-binding protein 3 isoform X1. (2155 aa) |
| | HELQ | Helicase POLQ-like isoform X1. (1079 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5 isoform X1. (1898 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | CHD5 | chromodomain-helicase-DNA-binding protein 5 isoform X1. (1954 aa) |
| | DMC1 | Meiotic recombination protein DMC1/LIM15 homolog isoform X1; Belongs to the RecA family. (340 aa) |
| | SMARCA5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa) |
| | SPO11 | Meiotic recombination protein SPO11 isoform X1. (395 aa) |
| | EP400 | E1A-binding protein p400 isoform X1. (3133 aa) |
| | SUB1 | Activated RNA polymerase II transcriptional coactivator p15. (127 aa) |
| | BLM | Bloom syndrome protein isoform X1. (1429 aa) |
| | DQX1 | ATP-dependent RNA helicase DQX1. (719 aa) |
| | ERCC6L2 | DNA excision repair protein ERCC-6-like 2 isoform X1. (1626 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa) |
| | UPF1 | Regulator of nonsense transcripts 1 isoform X1. (1127 aa) |
| | DSCC1 | Sister chromatid cohesion protein DCC1. (392 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (836 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1533 aa) |
| | SHPRH | E3 ubiquitin-protein ligase SHPRH isoform X1. (1685 aa) |
| | DDX1 | ATP-dependent RNA helicase DDX1. (740 aa) |
| | MLH1 | DNA mismatch repair protein Mlh1 isoform X1. (758 aa) |
| | SMARCA4 | Transcription activator BRG1 isoform X4. (1648 aa) |
| | MCM9 | DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1144 aa) |
| | ASCC3 | Activating signal cointegrator 1 complex subunit 3. (2201 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa) |
| | MCM8 | DNA helicase MCM8; Belongs to the MCM family. (832 aa) |
| | HFM1 | Probable ATP-dependent DNA helicase HFM1 isoform X4. (1476 aa) |
| | CHD9 | chromodomain-helicase-DNA-binding protein 9 isoform X1. (2902 aa) |
| | CUNH17orf64 | Uncharacterized protein C17orf64 homolog. (262 aa) |
| | RECQL4 | LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q4. (1211 aa) |
| | RAD51C | DNA repair protein RAD51 homolog 3 isoform X1. (371 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1620 aa) |
| | BRIP1 | Fanconi anemia group J protein. (1186 aa) |
