STRINGSTRING
CORO1C CORO1C RTN4R RTN4R NOG NOG EPHB2 EPHB2 NF2 NF2 ITGB1BP1 ITGB1BP1 YWHAH YWHAH TTC3 TTC3 NFATC4 NFATC4 NR2E1 NR2E1 SEMA3C SEMA3C EPHA7 EPHA7 SEMA6B SEMA6B NR1D1 NR1D1 FBXW9 FBXW9 PTPRS PTPRS KIFAP3 KIFAP3 SEMA4D SEMA4D S1PR3 S1PR3 SORL1 SORL1 TNR TNR LDLR LDLR GPR37L1 GPR37L1 BMPR1A BMPR1A SEMA4A SEMA4A KIAA0319 KIAA0319 SEMA4F SEMA4F LOC111168867 LOC111168867 LOC111169295 LOC111169295 TLX2 TLX2 CTNNB1 CTNNB1 TRIM11 TRIM11 WNT3A WNT3A SEMA4B SEMA4B SEMA6C SEMA6C GORASP1 GORASP1 THY1 THY1 LOC111168869 LOC111168869 LOC111169240 LOC111169240 SOX11 SOX11 GDI1 GDI1 SEMA3D SEMA3D SEMA3E SEMA3E LOC111168870 LOC111168870 CAV3 CAV3 DMTN DMTN FRZB FRZB SEMA4G SEMA4G MELTF MELTF NKX6-2 NKX6-2 VAX1 VAX1 PLXNA3 PLXNA3 CTDSP1 CTDSP1 PCM1 PCM1 DLX2 DLX2 SEMA5B SEMA5B HES1 HES1 SHB SHB NPR2 NPR2 NKX6-1 NKX6-1 DRAXIN DRAXIN LOC111186948 LOC111186948 APPL2 APPL2 IGF1 IGF1 FBXW7 FBXW7 BMP7 BMP7 RTN4 RTN4 FBLN1 FBLN1 TMEM98 TMEM98 ULK1 ULK1 SEMA4C SEMA4C NF1 NF1 NTN1 NTN1 HES5 HES5 LOC111185794 LOC111185794 RFLNB RFLNB AP1AR AP1AR EFNB3 EFNB3 F2 F2 LRP4 LRP4 PROX1 PROX1 SPRY4 SPRY4 EFNA5 EFNA5 SEMA6A SEMA6A FBN1 FBN1 WNT3 WNT3 CTNNA1 CTNNA1 SEMA6D SEMA6D FSTL4 FSTL4 TBX6 TBX6 PAX6 PAX6 PPP3CA PPP3CA RAPGEF2 RAPGEF2 ACTN4 ACTN4 DLL3 DLL3 RYK RYK TREM2 TREM2 SEMA5A SEMA5A ATOH1 ATOH1 LHX2 LHX2 DAAM2 DAAM2 PAEP PAEP SYNGAP1 SYNGAP1 NOTCH1 NOTCH1 PRTG PRTG PSEN1 PSEN1 LOC111178986 LOC111178986 CDK5 CDK5 SEMA7A SEMA7A TACSTD2 TACSTD2 EDNRB EDNRB PTN PTN WEE2 WEE2 KANK1 KANK1 BRINP1 BRINP1 SEMA3G SEMA3G LOC111177058 LOC111177058 DIP2B DIP2B PTHLH PTHLH DPYSL5 DPYSL5 HOOK3 HOOK3 LTF LTF SEMA3B SEMA3B IFRD2 IFRD2 DLX1 DLX1 SPART SPART WNT5A WNT5A DNAJB11 DNAJB11 SEMA3F SEMA3F RCC2 RCC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
RTN4RReticulon-4 receptor. (481 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (987 aa)
NF2Merlin isoform X3. (619 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (206 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
TTC3E3 ubiquitin-protein ligase TTC3 isoform X1. (2000 aa)
NFATC4LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 4. (901 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1 isoform X1. (385 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (998 aa)
SEMA6Bsemaphorin-6B; Belongs to the semaphorin family. (880 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
FBXW9F-box/WD repeat-containing protein 9 isoform X1. (461 aa)
PTPRSReceptor-type tyrosine-protein phosphatase S isoform X1. (1939 aa)
KIFAP3Kinesin-associated protein 3 isoform X1. (793 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (863 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
SORL1Sortilin-related receptor isoform X1. (2211 aa)
TNRtenascin-R isoform X1. (1358 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
GPR37L1Prosaposin receptor GPR37L1. (464 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SEMA4Asemaphorin-4A; Belongs to the semaphorin family. (762 aa)
KIAA0319Dyslexia-associated protein KIAA0319 homolog isoform X1. (1076 aa)
SEMA4Fsemaphorin-4F isoform X1; Belongs to the semaphorin family. (789 aa)
LOC111168867semaphorin-3A isoform X1. (306 aa)
LOC111169295RE1-silencing transcription factor-like isoform X1. (981 aa)
TLX2T-cell leukemia homeobox protein 2. (284 aa)
CTNNB1Catenin beta-1. (781 aa)
TRIM11E3 ubiquitin-protein ligase TRIM11 isoform X1. (468 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SEMA4Bsemaphorin-4B; Belongs to the semaphorin family. (822 aa)
SEMA6Csemaphorin-6C isoform X5; Belongs to the semaphorin family. (966 aa)
GORASP1Golgi reassembly-stacking protein 1 isoform X1. (486 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
LOC111168869semaphorin-3A-like; Belongs to the semaphorin family. (273 aa)
LOC111169240RE1-silencing transcription factor-like isoform X2. (976 aa)
SOX11Transcription factor SOX. (454 aa)
GDI1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (447 aa)
SEMA3Dsemaphorin-3D isoform X1; Belongs to the semaphorin family. (777 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (775 aa)
LOC111168870semaphorin-3A-like; Belongs to the semaphorin family. (249 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
DMTNDematin isoform X1. (405 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
SEMA4Gsemaphorin-4G isoform X1; Belongs to the semaphorin family. (843 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (739 aa)
NKX6-2Homeobox protein Nkx-6.2. (277 aa)
VAX1Ventral anterior homeobox 1 isoform X1. (331 aa)
PLXNA3plexin-A3. (1872 aa)
CTDSP1Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X1. (261 aa)
PCM1Pericentriolar material 1 protein isoform X1. (2196 aa)
DLX2Homeobox protein DLX-2 isoform X1. (333 aa)
SEMA5Bsemaphorin-5B isoform X1. (1093 aa)
HES1Transcription factor HES-1. (280 aa)
SHBSH2 domain-containing adapter protein B. (507 aa)
NPR2Guanylate cyclase. (1056 aa)
NKX6-1Homeobox protein Nkx-6.1. (365 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (350 aa)
LOC111186948refilin-A. (135 aa)
APPL2DCC-interacting protein 13-beta isoform X2. (661 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (707 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
RTN4Reticulon. (1192 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
TMEM98Transmembrane protein 98. (226 aa)
ULK1Serine/threonine-protein kinase ULK1 isoform X1. (1055 aa)
SEMA4Csemaphorin-4C isoform X1; Belongs to the semaphorin family. (945 aa)
NF1Neurofibromin isoform X1. (2873 aa)
NTN1Netrin-1. (604 aa)
HES5Transcription factor HES-5 isoform X1. (205 aa)
LOC111185794C-C motif chemokine. (97 aa)
RFLNBrefilin-B. (217 aa)
AP1ARAP-1 complex-associated regulatory protein isoform X1. (302 aa)
EFNB3ephrin-B3 isoform X1; Belongs to the ephrin family. (340 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
PROX1Prospero homeobox protein 1 isoform X1. (738 aa)
SPRY4Protein sprouty homolog 4. (299 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1044 aa)
FBN1Fibrillin-1 isoform X1. (2871 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
CTNNA1Catenin alpha-1. (906 aa)
SEMA6Dsemaphorin-6D isoform X1; Belongs to the semaphorin family. (1073 aa)
FSTL4Follistatin-related protein 4 isoform X1. (704 aa)
TBX6T-box transcription factor TBX6 isoform X1. (462 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X1. (1651 aa)
ACTN4Alpha-actinin-4 isoform X5. (933 aa)
DLL3Delta-like protein 3. (586 aa)
RYKTyrosine-protein kinase RYK isoform X1. (609 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (294 aa)
SEMA5Asemaphorin-5A isoform X1. (1079 aa)
ATOH1Protein atonal homolog 1. (352 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
DAAM2Disheveled-associated activator of morphogenesis 2 isoform X1. (1097 aa)
PAEPGlycodelin; Belongs to the calycin superfamily. Lipocalin family. (180 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP isoform X1. (1345 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
PRTGProtogenin. (1200 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
LOC111178986LOW QUALITY PROTEIN: catenin alpha-1-like. (908 aa)
CDK5Cyclin-dependent-like kinase 5; Belongs to the protein kinase superfamily. (292 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (323 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
PTNPleiotrophin isoform X1. (168 aa)
WEE2Wee1-like protein kinase 2. (419 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X3. (1351 aa)
BRINP1BMP/retinoic acid-inducible neural-specific protein 1. (761 aa)
SEMA3Gsemaphorin-3G isoform X1; Belongs to the semaphorin family. (773 aa)
LOC111177058Beta-lactoglobulin-2-like; Belongs to the calycin superfamily. Lipocalin family. (188 aa)
DIP2BDisco-interacting protein 2 homolog B isoform X1. (1576 aa)
PTHLHParathyroid hormone-related protein. (177 aa)
DPYSL5LOW QUALITY PROTEIN: dihydropyrimidinase-related protein 5. (564 aa)
HOOK3Protein Hook homolog 3 isoform X5. (740 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
SEMA3Bsemaphorin-3B isoform X1; Belongs to the semaphorin family. (748 aa)
IFRD2Interferon-related developmental regulator 2 isoform X1. (442 aa)
DLX1Homeobox protein DLX-1 isoform X1. (255 aa)
SPARTSpartin. (668 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
DNAJB11dnaJ homolog subfamily B member 11. (358 aa)
SEMA3Fsemaphorin-3F isoform X1; Belongs to the semaphorin family. (785 aa)
RCC2Protein RCC2 isoform X1. (543 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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