node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGT | AGTR1 | A0A2Y9LH34 | A0A140GMY9 | Angiotensinogen; Belongs to the serpin family. | Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. | 0.999 |
AGTR1 | AGT | A0A140GMY9 | A0A2Y9LH34 | Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. | Angiotensinogen; Belongs to the serpin family. | 0.999 |
AGTR1 | APOB | A0A140GMY9 | A0A2Y9NAV4 | Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. | Apolipoprotein B-100. | 0.514 |
APOB | AGTR1 | A0A2Y9NAV4 | A0A140GMY9 | Apolipoprotein B-100. | Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. | 0.514 |
APOB | LPL | A0A2Y9NAV4 | A0A2Y9M8T8 | Apolipoprotein B-100. | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | 0.623 |
APOB | MSR1 | A0A2Y9NAV4 | A0A2Y9NC40 | Apolipoprotein B-100. | Macrophage scavenger receptor types I and II isoform X1. | 0.643 |
CSF1 | CSF2 | A0A2Y9PBL1 | A0A2Y9PGP5 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] | Granulocyte-macrophage colony-stimulating factor. | 0.831 |
CSF1 | MSR1 | A0A2Y9PBL1 | A0A2Y9NC40 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] | Macrophage scavenger receptor types I and II isoform X1. | 0.438 |
CSF2 | CSF1 | A0A2Y9PGP5 | A0A2Y9PBL1 | Granulocyte-macrophage colony-stimulating factor. | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] | 0.831 |
ITGAV | ITGB3 | A0A2Y9MPN9 | A0A2Y9PCY7 | Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. | Integrin beta; Belongs to the integrin beta chain family. | 0.999 |
ITGAV | MSR1 | A0A2Y9MPN9 | A0A2Y9NC40 | Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. | Macrophage scavenger receptor types I and II isoform X1. | 0.576 |
ITGB3 | ITGAV | A0A2Y9PCY7 | A0A2Y9MPN9 | Integrin beta; Belongs to the integrin beta chain family. | Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. | 0.999 |
LOC111185769 | PLA2G3 | A0A2Y9Q1M1 | A0A2Y9LAE0 | Arachidonate 15-lipoxygenase B-like. | Group 3 secretory phospholipase A2 isoform X1. | 0.908 |
LOC111185769 | PLA2G5 | A0A2Y9Q1M1 | A0A2Y9LD55 | Arachidonate 15-lipoxygenase B-like. | Phospholipase A(2). | 0.901 |
LPL | APOB | A0A2Y9M8T8 | A0A2Y9NAV4 | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | Apolipoprotein B-100. | 0.623 |
LPL | PPARA | A0A2Y9M8T8 | A0A2Y9Q177 | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | Peroxisome proliferator-activated receptor alpha. | 0.526 |
MAPK9 | NFKBIA | A0A2Y9MJ04 | A0A2Y9NB16 | Mitogen-activated protein kinase. | NF-kappa-B inhibitor alpha. | 0.505 |
MSR1 | APOB | A0A2Y9NC40 | A0A2Y9NAV4 | Macrophage scavenger receptor types I and II isoform X1. | Apolipoprotein B-100. | 0.643 |
MSR1 | CSF1 | A0A2Y9NC40 | A0A2Y9PBL1 | Macrophage scavenger receptor types I and II isoform X1. | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] | 0.438 |
MSR1 | ITGAV | A0A2Y9NC40 | A0A2Y9MPN9 | Macrophage scavenger receptor types I and II isoform X1. | Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. | 0.576 |