STRINGSTRING
DYRK1B DYRK1B PPP3CA PPP3CA SPG11 SPG11 PLD3 PLD3 SORT1 SORT1 NPHS1 NPHS1 CAV2 CAV2 ITGB1 ITGB1 PTGFRN PTGFRN ADAMTS15 ADAMTS15 SMYD3 SMYD3 MYMX MYMX SMO SMO KLF5 KLF5 KEL KEL CAPN2 CAPN2 MYMK MYMK WNT1 WNT1 SHH SHH WNT10B WNT10B R3HDM2 R3HDM2 ADAMTS5 ADAMTS5 TANC1 TANC1 LMOD3 LMOD3 MYOF MYOF SIX1 SIX1 ACTN1 ACTN1 STAC3 STAC3 DNER DNER SIX4 SIX4 KLHL41 KLHL41 ACTA2 ACTA2 DOCK1 DOCK1 CAV3 CAV3 PLEKHO1 PLEKHO1 BIN3 BIN3 RIPOR2 RIPOR2 CACNA1S CACNA1S IGF1 IGF1 MYH9 MYH9 TMEM182 TMEM182 FER1L5 FER1L5 NFATC2 NFATC2 BCL2 BCL2 P2RX2 P2RX2 MEF2C MEF2C PPP3CB PPP3CB CD81 CD81 MYORG MYORG SELENON SELENON HOMER1 HOMER1 DOCK2 DOCK2 DOCK5 DOCK5 ADGRB3 ADGRB3 KLHL40 KLHL40 MYOD1 MYOD1 LOC111165064 LOC111165064 CDON CDON
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DYRK1BDual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1. (686 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
SPG11Spatacsin isoform X1. (2443 aa)
PLD3Phospholipase D3. (490 aa)
SORT1Sortilin. (864 aa)
NPHS1Nephrin. (1270 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PTGFRNProstaglandin F2 receptor negative regulator. (879 aa)
ADAMTS15A disintegrin and metalloproteinase with thrombospondin motifs 15. (950 aa)
SMYD3Histone-lysine N-methyltransferase SMYD3. (428 aa)
MYMXUncharacterized LOC101929726 homolog. (84 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
KLF5Krueppel-like factor 5. (454 aa)
KELKell blood group glycoprotein isoform X1. (800 aa)
CAPN2Calpain-2 catalytic subunit isoform X1; Belongs to the peptidase C2 family. (703 aa)
MYMKProtein myomaker. (221 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
R3HDM2R3H domain-containing protein 2 isoform X1. (1048 aa)
ADAMTS5A disintegrin and metalloproteinase with thrombospondin motifs 5. (931 aa)
TANC1Protein TANC1 isoform X1. (1889 aa)
LMOD3Leiomodin-3. (564 aa)
MYOFMyoferlin isoform X1. (2080 aa)
SIX1Homeobox protein SIX1. (284 aa)
ACTN1Alpha-actinin-1 isoform X2. (914 aa)
STAC3SH3 and cysteine-rich domain-containing protein 3 isoform X1. (360 aa)
DNERDelta and Notch-like epidermal growth factor-related receptor. (736 aa)
SIX4Homeobox protein SIX4 isoform X1. (790 aa)
KLHL41Kelch-like protein 41. (606 aa)
ACTA2Actin, aortic smooth muscle. (466 aa)
DOCK1Dedicator of cytokinesis protein 1 isoform X1; Belongs to the DOCK family. (1886 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PLEKHO1Pleckstrin homology domain-containing family O member 1 isoform X1. (423 aa)
BIN3Bridging integrator 3 isoform X1. (253 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X2. (1048 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
TMEM182Transmembrane protein 182 isoform X1. (229 aa)
FER1L5Fer-1-like protein 5. (2032 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (943 aa)
BCL2Apoptosis regulator Bcl-2. (233 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (479 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X6. (483 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CD81Tetraspanin. (236 aa)
MYORGUncharacterized family 31 glucosidase KIAA1161 homolog isoform X1; Belongs to the glycosyl hydrolase 31 family. (791 aa)
SELENONSelenoprotein N. (557 aa)
HOMER1Homer protein homolog 1 isoform X1. (354 aa)
DOCK2Dedicator of cytokinesis protein 2 isoform X1; Belongs to the DOCK family. (1828 aa)
DOCK5Dedicator of cytokinesis protein 5 isoform X1; Belongs to the DOCK family. (1869 aa)
ADGRB3Adhesion G protein-coupled receptor B3 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
KLHL40Kelch-like protein 40. (623 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
LOC111165064Plectin isoform X1. (4685 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes isoform X1. (1279 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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