STRINGSTRING
AP3B1 AP3B1 CORO1C CORO1C CHMP5 CHMP5 TBC1D10A TBC1D10A CLEC16A CLEC16A RASSF9 RASSF9 ITSN1 ITSN1 TMEM50B TMEM50B CUNH16orf62 CUNH16orf62 SNX7 SNX7 CLTC CLTC HEATR5A HEATR5A CHMP1B CHMP1B SNX3 SNX3 WASHC5 WASHC5 TMEM50A TMEM50A DSCR3 DSCR3 TBC1D14 TBC1D14 KIAA1107 KIAA1107 CMTM6 CMTM6 RAB11B RAB11B AP3D1 AP3D1 LYST LYST DENND1C DENND1C RAB5C RAB5C VPS35 VPS35 PLEKHJ1 PLEKHJ1 SNF8 SNF8 REPS1 REPS1 CHMP4A CHMP4A VPS28 VPS28 UBXN6 UBXN6 VTA1 VTA1 VPS25 VPS25 SPAG9 SPAG9 STX10 STX10 CHMP4C CHMP4C RAB13 RAB13 PQLC1 PQLC1 SNX9 SNX9 VPS26B VPS26B STX6 STX6 SNX12 SNX12 EPG5 EPG5 ALMS1 ALMS1 LOC111168424 LOC111168424 DENND5A DENND5A RAB8A RAB8A RBSN RBSN EPS15L1 EPS15L1 MICALL2 MICALL2 MVB12A MVB12A SNX8 SNX8 LOC111168748 LOC111168748 WAS WAS TMCC1 TMCC1 ARHGAP44 ARHGAP44 SNX27 SNX27 GRIPAP1 GRIPAP1 LOC111168216 LOC111168216 RAB7A RAB7A WASHC2A WASHC2A REPS2 REPS2 CHMP2A CHMP2A RAB9A RAB9A BET1L BET1L LOC111171019 LOC111171019 NSG1 NSG1 LOC111171166 LOC111171166 DCTN1 DCTN1 RAB17 RAB17 CALY CALY CCDC22 CCDC22 RAB9B RAB9B BLOC1S2 BLOC1S2 VTI1A VTI1A VTI1B VTI1B AP5Z1 AP5Z1 ALS2 ALS2 RNF126 RNF126 LAMTOR1 LAMTOR1 AP5M1 AP5M1 ARF6 ARF6 LEPROTL1 LEPROTL1 ATP6AP1 ATP6AP1 FAM45A FAM45A SNX4 SNX4 BLOC1S1 BLOC1S1 RIC1 RIC1 DPY30 DPY30 EHD3 EHD3 VPS36 VPS36 GRIP1 GRIP1 PTPN23 PTPN23 HEATR5B HEATR5B SNX6 SNX6 PREPL PREPL EPS15 EPS15 LAPTM4A LAPTM4A ABCA2 ABCA2 GOLT1B GOLT1B ALS2CL ALS2CL DENND1B DENND1B RAB10 RAB10 RAB8B RAB8B SNX1 SNX1 SNX30 SNX30 ZFYVE9 ZFYVE9 LOC111178657 LOC111178657 STAM STAM LOC111178266 LOC111178266 SDCCAG3 SDCCAG3 LRRC1 LRRC1 CHMP2B CHMP2B CLN5 CLN5 RAB14 RAB14 WASHC1 WASHC1 RAB6B RAB6B VPS52 VPS52 SNX33 SNX33 RAB18 RAB18 RAB11A RAB11A LEPROT LEPROT SORT1 SORT1 TBC1D17 TBC1D17 VPS4A VPS4A VPS4B VPS4B EHD2 EHD2 MYO5B MYO5B ANKRD27 ANKRD27 ANKRD63 ANKRD63 CHMP1A CHMP1A LAPTM4B LAPTM4B TBC1D23 TBC1D23 LMTK2 LMTK2 VPS50 VPS50 TBC1D10B TBC1D10B UBE2O UBE2O HGS HGS VPS39 VPS39 SNX32 SNX32 TMEM87A TMEM87A EHD4 EHD4 SNX2 SNX2 TBC1D10C TBC1D10C CHMP6 CHMP6 EHD1 EHD1 STX5 STX5 RAB6A RAB6A PICALM PICALM VPS16 VPS16 SNX5 SNX5 VPS26A VPS26A RAB11FIP3 RAB11FIP3 CCDC93 CCDC93 YKT6 YKT6 RAB7B RAB7B VPS51 VPS51 NSG2 NSG2 AP5B1 AP5B1 RAB29 RAB29 GOLT1A GOLT1A ANKFY1 ANKFY1 ZFYVE16 ZFYVE16 ARHGAP1 ARHGAP1 VCP VCP ABCA1 ABCA1 RGP1 RGP1 WASHC4 WASHC4 VAMP3 VAMP3 RAB35 RAB35 ARL1 ARL1 RAB22A RAB22A VPS54 VPS54 GCC2 GCC2 TMEM87B TMEM87B FAM109B FAM109B RAB11FIP4 RAB11FIP4 VPS53 VPS53 TUSC5 TUSC5 FAM109A FAM109A SNX18 SNX18 LOC111185565 LOC111185565 STX16 STX16 CHMP7 CHMP7 GGA1 GGA1 BAIAP3 BAIAP3 ANKRD50 ANKRD50 VPS29 VPS29 ARFRP1 ARFRP1 TRAPPC10 TRAPPC10 SGSM2 SGSM2 RILP RILP AP5S1 AP5S1 CHMP4B CHMP4B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
TBC1D10ATBC1 domain family member 10A. (506 aa)
CLEC16AProtein CLEC16A isoform X1. (1048 aa)
RASSF9Ras association domain-containing protein 9. (435 aa)
ITSN1Intersectin-1 isoform X1. (1715 aa)
TMEM50BTransmembrane protein 50B isoform X1. (158 aa)
CUNH16orf62UPF0505 protein C16orf62 homolog isoform X1. (987 aa)
SNX7Sorting nexin-7 isoform X1. (451 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
HEATR5AHEAT repeat-containing protein 5A isoform X1. (2054 aa)
CHMP1BCharged multivesicular body protein 1b. (199 aa)
SNX3Sorting nexin-3. (162 aa)
WASHC5WASH complex subunit 5 isoform X1. (1159 aa)
TMEM50ATransmembrane protein 50A isoform X1. (177 aa)
DSCR3Down syndrome critical region protein 3 isoform X1. (297 aa)
TBC1D14TBC1 domain family member 14 isoform X2. (669 aa)
KIAA1107Uncharacterized protein KIAA1107 homolog isoform X1. (1808 aa)
CMTM6CKLF-like MARVEL transmembrane domain-containing protein 6. (178 aa)
RAB11BRas-related protein Rab-11B. (218 aa)
AP3D1AP-3 complex subunit delta-1 isoform X1. (1204 aa)
LYSTLysosomal-trafficking regulator isoform X1. (3861 aa)
DENND1CDENN domain-containing protein 1C isoform X1. (854 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
PLEKHJ1Pleckstrin homology domain-containing family J member 1 isoform X1. (247 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
REPS1ralBP1-associated Eps domain-containing protein 1 isoform X1. (802 aa)
CHMP4ACharged multivesicular body protein 4a. (222 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
UBXN6UBX domain-containing protein 6 isoform X1. (441 aa)
VTA1Vacuolar protein sorting-associated protein VTA1 homolog. (309 aa)
VPS25Vacuolar protein-sorting-associated protein 25. (176 aa)
SPAG9C-Jun-amino-terminal kinase-interacting protein 4 isoform X1. (1334 aa)
STX10Syntaxin-10 isoform X1. (249 aa)
CHMP4CCharged multivesicular body protein 4c. (237 aa)
RAB13Ras-related protein Rab-13. (203 aa)
PQLC1PQ-loop repeat-containing protein 1 isoform X1. (270 aa)
SNX9Sorting nexin. (594 aa)
VPS26BVacuolar protein sorting-associated protein 26B. (336 aa)
STX6Syntaxin-6 isoform X3; Belongs to the syntaxin family. (255 aa)
SNX12Sorting nexin-12. (162 aa)
EPG5Ectopic P granules protein 5 homolog isoform X2. (2594 aa)
ALMS1Alstrom syndrome protein 1 isoform X1. (4198 aa)
LOC111168424Zinc finger protein RFP. (513 aa)
DENND5ADENN domain-containing protein 5A. (1288 aa)
RAB8ARas-related protein Rab-8A. (207 aa)
RBSNRabenosyn-5 isoform X1. (784 aa)
EPS15L1Epidermal growth factor receptor substrate 15-like 1 isoform X1. (947 aa)
MICALL2MICAL-like protein 2 isoform X1. (953 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
SNX8Sorting nexin-8 isoform X2. (459 aa)
LOC111168748Annexin. (327 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
TMCC1Transmembrane and coiled-coil domains protein 1 isoform X1. (653 aa)
ARHGAP44Rho GTPase-activating protein 44 isoform X1. (809 aa)
SNX27Sorting nexin-27. (543 aa)
GRIPAP1GRIP1-associated protein 1 isoform X1. (842 aa)
LOC111168216LOW QUALITY PROTEIN: Down syndrome critical region protein 3-like. (270 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
WASHC2AWASH complex subunit 2A isoform X1. (1338 aa)
REPS2ralBP1-associated Eps domain-containing protein 2 isoform X1. (648 aa)
CHMP2ACharged multivesicular body protein 2a isoform X1. (305 aa)
RAB9ARas-related protein Rab-9A. (201 aa)
BET1LBET1-like protein isoform X1. (115 aa)
LOC111171019Glutamate receptor-interacting protein 1-like. (206 aa)
NSG1Neuron-specific protein family member 1. (185 aa)
LOC111171166LOW QUALITY PROTEIN: testis-specific protein TEX28-like. (252 aa)
DCTN1Dynactin subunit 1 isoform X6. (1281 aa)
RAB17Ras-related protein Rab-17. (213 aa)
CALYNeuron-specific vesicular protein calcyon isoform X1. (269 aa)
CCDC22Coiled-coil domain-containing protein 22 isoform X1. (627 aa)
RAB9BRas-related protein Rab-9B. (201 aa)
BLOC1S2Biogenesis of lysosome-related organelles complex 1 subunit 2. (142 aa)
VTI1AVesicle transport through interaction with t-SNAREs homolog 1A isoform X1. (229 aa)
VTI1BVesicle transport through interaction with t-SNAREs homolog 1B. (232 aa)
AP5Z1AP-5 complex subunit zeta-1 isoform X1. (890 aa)
ALS2Alsin isoform X1. (1681 aa)
RNF126E3 ubiquitin-protein ligase RNF126 isoform X1. (312 aa)
LAMTOR1Ragulator complex protein LAMTOR1. (161 aa)
AP5M1AP-5 complex subunit mu-1 isoform X1; Belongs to the adaptor complexes medium subunit family. (543 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
LEPROTL1Leptin receptor overlapping transcript-like 1. (131 aa)
ATP6AP1V-type proton ATPase subunit S1. (469 aa)
FAM45AProtein FAM45A isoform X1. (357 aa)
SNX4Sorting nexin-4. (450 aa)
BLOC1S1Biogenesis of lysosome-related organelles complex 1 subunit 1. (125 aa)
RIC1RAB6A-GEF complex partner protein 1 isoform X1. (1421 aa)
DPY30Protein dpy-30 homolog. (99 aa)
EHD3EH domain-containing protein 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
VPS36Vacuolar protein-sorting-associated protein 36. (386 aa)
GRIP1Glutamate receptor-interacting protein 1. (886 aa)
PTPN23Tyrosine-protein phosphatase non-receptor type 23 isoform X1. (1630 aa)
HEATR5BHEAT repeat-containing protein 5B isoform X1. (2069 aa)
SNX6Sorting nexin-6. (389 aa)
PREPLProlyl endopeptidase-like isoform X1. (727 aa)
EPS15Epidermal growth factor receptor substrate 15 isoform X1. (902 aa)
LAPTM4ALysosomal-associated transmembrane protein 4A. (233 aa)
ABCA2ATP-binding cassette sub-family A member 2 isoform X1. (2438 aa)
GOLT1BVesicle transport protein GOT1B. (138 aa)
ALS2CLALS2 C-terminal-like protein isoform X2. (997 aa)
DENND1BDENN domain-containing protein 1B isoform X1. (776 aa)
RAB10Ras-related protein Rab-10. (200 aa)
RAB8BRas-related protein Rab-8B isoform X1. (207 aa)
SNX1Sorting nexin-1 isoform X1. (522 aa)
SNX30Sorting nexin-30. (437 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1423 aa)
LOC111178657Leucine-rich repeat-containing protein 1-like isoform X1. (174 aa)
STAMSignal transducing adapter molecule 1. (526 aa)
LOC111178266LOW QUALITY PROTEIN: charged multivesicular body protein 1b-2-like. (205 aa)
SDCCAG3Serologically defined colon cancer antigen 3 isoform X1. (430 aa)
LRRC1Leucine-rich repeat-containing protein 1. (395 aa)
CHMP2BCharged multivesicular body protein 2b. (213 aa)
CLN5Ceroid-lipofuscinosis neuronal protein 5. (358 aa)
RAB14Ras-related protein Rab-14. (215 aa)
WASHC1WASH complex subunit 1 isoform X1. (494 aa)
RAB6BRas-related protein Rab-6B. (208 aa)
VPS52Vacuolar protein sorting-associated protein 52 homolog isoform X1. (723 aa)
SNX33Sorting nexin. (574 aa)
RAB18Ras-related protein Rab-18. (206 aa)
RAB11ARas-related protein Rab-11A isoform X1. (218 aa)
LEPROTLeptin receptor gene-related protein. (131 aa)
SORT1Sortilin. (864 aa)
TBC1D17TBC1 domain family member 17 isoform X1. (655 aa)
VPS4AVacuolar protein sorting-associated protein 4A isoform X1; Belongs to the AAA ATPase family. (437 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (444 aa)
EHD2EH domain-containing protein 2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
MYO5BUnconventional myosin-Vb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
ANKRD27Ankyrin repeat domain-containing protein 27 isoform X1. (1100 aa)
ANKRD63Ankyrin repeat domain-containing protein 63. (382 aa)
CHMP1ACharged multivesicular body protein 1a. (196 aa)
LAPTM4BLysosomal-associated transmembrane protein 4B isoform X1. (251 aa)
TBC1D23TBC1 domain family member 23 isoform X1. (700 aa)
LMTK2Serine/threonine-protein kinase LMTK2 isoform X1. (1497 aa)
VPS50Syndetin isoform X1. (964 aa)
TBC1D10BTBC1 domain family member 10B. (784 aa)
UBE2O(E3-independent) E2 ubiquitin-conjugating enzyme isoform X1. (1300 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
VPS39vam6/Vps39-like protein isoform X1. (875 aa)
SNX32Sorting nexin; Involved in several stages of intracellular trafficking. (426 aa)
TMEM87ATransmembrane protein 87A isoform X1. (556 aa)
EHD4EH domain-containing protein 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa)
SNX2Sorting nexin-2. (519 aa)
TBC1D10CCarabin isoform X1. (458 aa)
CHMP6Charged multivesicular body protein 6 isoform X1. (202 aa)
EHD1EH domain-containing protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
STX5Syntaxin-5; Belongs to the syntaxin family. (355 aa)
RAB6ARas-related protein Rab-6A isoform X1. (208 aa)
PICALMPhosphatidylinositol-binding clathrin assembly protein isoform X1. (696 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
VPS26AVacuolar protein sorting-associated protein 26A isoform X1. (417 aa)
RAB11FIP3Rab11 family-interacting protein 3 isoform X1. (734 aa)
CCDC93Coiled-coil domain-containing protein 93 isoform X1. (631 aa)
YKT6Synaptobrevin homolog YKT6 isoform X1; Belongs to the synaptobrevin family. (202 aa)
RAB7BRas-related protein Rab-7b isoform X1. (210 aa)
VPS51Vacuolar protein sorting-associated protein 51 homolog isoform X1. (781 aa)
NSG2Neuron-specific protein family member 2. (171 aa)
AP5B1AP-5 complex subunit beta-1. (877 aa)
RAB29Ras-related protein Rab-7L1 isoform X1. (203 aa)
GOLT1AVesicle transport protein GOT1A. (132 aa)
ANKFY1Rabankyrin-5 isoform X1. (1170 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16 isoform X1. (1546 aa)
ARHGAP1Rho GTPase-activating protein 1. (433 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (806 aa)
ABCA1ATP-binding cassette sub-family A member 1 isoform X1. (2273 aa)
RGP1RAB6A-GEF complex partner protein 2 isoform X3. (418 aa)
WASHC4WASH complex subunit 4. (1173 aa)
VAMP3Vesicle-associated membrane protein 3. (104 aa)
RAB35Ras-related protein Rab-35 isoform X1. (201 aa)
ARL1ADP-ribosylation factor-like protein 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
RAB22ARas-related protein Rab-22A isoform X1. (198 aa)
VPS54Vacuolar protein sorting-associated protein 54 isoform X1. (1001 aa)
GCC2GRIP and coiled-coil domain-containing protein 2 isoform X1. (1680 aa)
TMEM87BTransmembrane protein 87B isoform X3. (549 aa)
FAM109BSesquipedalian-2. (262 aa)
RAB11FIP4Rab11 family-interacting protein 4 isoform X1. (637 aa)
VPS53Vacuolar protein sorting-associated protein 53 homolog. (832 aa)
TUSC5Tumor suppressor candidate 5. (204 aa)
FAM109ASesquipedalian-1. (217 aa)
SNX18Sorting nexin. (625 aa)
LOC111185565Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (277 aa)
STX16Syntaxin-16 isoform X1; Belongs to the syntaxin family. (309 aa)
CHMP7Charged multivesicular body protein 7. (450 aa)
GGA1ADP-ribosylation factor-binding protein GGA1 isoform X1. (648 aa)
BAIAP3BAI1-associated protein 3 isoform X1. (1177 aa)
ANKRD50Ankyrin repeat domain-containing protein 50. (1428 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
ARFRP1ADP-ribosylation factor-related protein 1 isoform X1. (201 aa)
TRAPPC10Trafficking protein particle complex subunit 10 isoform X1. (1259 aa)
SGSM2Small G protein signaling modulator 2 isoform X1. (1098 aa)
RILPRab-interacting lysosomal protein isoform X1. (447 aa)
AP5S1AP-5 complex subunit sigma-1. (199 aa)
CHMP4BCharged multivesicular body protein 4b. (224 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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