STRINGSTRING
DDX4 DDX4 DDX47 DDX47 ORC1 ORC1 NVL NVL TOR1B TOR1B MSH2 MSH2 KIF12 KIF12 ATP12A ATP12A ATP8A2 ATP8A2 HSPA14 HSPA14 KIF5B KIF5B MYO1E MYO1E ATP7A ATP7A TOR2A TOR2A HSPA5 HSPA5 HSPA13 HSPA13 CUNH9orf84 CUNH9orf84 TOR4A TOR4A PIF1 PIF1 KIF23 KIF23 YME1L1 YME1L1 ATP6V1G1 ATP6V1G1 PEX6 PEX6 ATP2C2 ATP2C2 ATF7IP ATF7IP TOR1A TOR1A ATP1A1 ATP1A1 CFTR CFTR CLPX CLPX CEP41 CEP41 TRIP13 TRIP13 DHX38 DHX38 VPS4A VPS4A LOC111179605 LOC111179605 VPS4B VPS4B ERCC2 ERCC2 PSMC4 PSMC4 HSP90AB1 HSP90AB1 MOV10 MOV10 ATP8B1 ATP8B1 PFN2 PFN2 DHX36 DHX36 KIF6 KIF6 MCM3 MCM3 SMARCAD1 SMARCAD1 CHD1L CHD1L SPG7 SPG7 DDX19B DDX19B ATP4A ATP4A ATP8B4 ATP8B4 RFC2 RFC2 WRNIP1 WRNIP1 SRCAP SRCAP INO80 INO80 CCT6A CCT6A ATP1A3 ATP1A3 CHD8 CHD8 KIF22 KIF22 PMS2 PMS2 RUVBL2 RUVBL2 DHX34 DHX34 UPK3B UPK3B RAD50 RAD50 KIF3A KIF3A PEX1 PEX1 G3BP1 G3BP1 PSMC5 PSMC5 KIF13A KIF13A HSPA9 HSPA9 NSF NSF SPATA5L1 SPATA5L1 EIF4A3 EIF4A3 CARNS1 CARNS1 MCM7 MCM7 ERCC3 ERCC3 DNA2 DNA2 KIF20A KIF20A ATP2A1 ATP2A1 IGHMBP2 IGHMBP2 RECQL5 RECQL5 PSMC3 PSMC3 KIF19 KIF19 FIGNL1 FIGNL1 DHX9 DHX9 ATP2B4 ATP2B4 ATP10B ATP10B CHD1 CHD1 CHD6 CHD6 RHOBTB3 RHOBTB3 KIF13B KIF13B DDX56 DDX56 CHD7 CHD7 MARVELD2 MARVELD2 ATP2A3 ATP2A3 AK6 AK6 KIF16B KIF16B LOC111186011 LOC111186011 CHTF18 CHTF18 TRAP1 TRAP1 LOC111187281 LOC111187281 CCT4 CCT4 CHD2 CHD2 RTEL1 RTEL1 DHX29 DHX29 DDX27 DDX27 CHD3 CHD3 EIF4A1 EIF4A1 ATAD5 ATAD5 KIF1C KIF1C MCM5 MCM5 SPATA5 SPATA5 CHD5 CHD5 SMC1B SMC1B SMARCA5 SMARCA5 ATP9A ATP9A DDX55 DDX55 RFC5 RFC5 SMC2 SMC2 ATP2A2 ATP2A2 LOC111188071 LOC111188071 ATP13A2 ATP13A2 LOC111187147 LOC111187147 LOC111187138 LOC111187138 ATP10A ATP10A HSP90B1 HSP90B1 VCP VCP DDX54 DDX54 SMCHD1 SMCHD1 DDX52 DDX52 KIF2B KIF2B MYO19 MYO19 ALPL ALPL ATP2B1 ATP2B1 MDN1 MDN1 PSMC2 PSMC2 ATAD2 ATAD2 LONP2 LONP2 RECQL4 RECQL4 CUNH17orf64 CUNH17orf64 CHD9 CHD9 MORC3 MORC3 MORC2 MORC2 ABCD3 ABCD3 ABCA4 ABCA4 DNAH6 DNAH6 KIFC2 KIFC2 AFG1L AFG1L DDX25 DDX25 MCM8 MCM8 ATP11C ATP11C LONP1 LONP1 DDX3X DDX3X ABCB10 ABCB10 NTPCR NTPCR ASCC3 ASCC3 MCM9 MCM9 SMARCA4 SMARCA4 MLH1 MLH1 KIF15 KIF15 DDX1 DDX1 ATP13A1 ATP13A1 MCM4 MCM4 LOC111166987 LOC111166987 TMEM59L TMEM59L CCT3 CCT3 NAV3 NAV3 LOC111166986 LOC111166986 TCP1 TCP1 ABCG4 ABCG4 UPF1 UPF1 DDX39A DDX39A TOR3A TOR3A ERMARD ERMARD ATP8B3 ATP8B3 KATNA1 KATNA1 ATP2C1 ATP2C1 ATP8B2 ATP8B2 CCT7 CCT7 ATP2B2 ATP2B2 DHX58 DHX58 KATNAL2 KATNAL2 ASNA1 ASNA1 DQX1 DQX1 KIF7 KIF7 ATP10D ATP10D ATP9B ATP9B DDX39B DDX39B LOC111170664 LOC111170664 LOC111170662 LOC111170662 ATP8A1 ATP8A1 KIF18B KIF18B CCT6B CCT6B ERCC6L ERCC6L LOC111171193 LOC111171193 KIF21B KIF21B ABCD1 ABCD1 RUVBL1 RUVBL1 MCM2 MCM2 IQCA1 IQCA1 KIF1A KIF1A CUNH10orf88 CUNH10orf88 ATP13A4 ATP13A4 SMC1A SMC1A ATAD1 ATAD1 MORC4 MORC4 IFIH1 IFIH1 LOC111172806 LOC111172806 SMC3 SMC3 PSMC6 PSMC6 PMS1 PMS1 HSPA6 HSPA6 BTAF1 BTAF1 CLPB CLPB RFC1 RFC1 LOC111171833 LOC111171833 ATP2B3 ATP2B3 ATP6V1G2 ATP6V1G2 EIF4A2 EIF4A2 TM4SF19 TM4SF19 KIF5A KIF5A LOC111171395 LOC111171395 FIGNL2 FIGNL2 ABCD2 ABCD2 ABCB6 ABCB6 LOC111172805 LOC111172805 OLA1 OLA1 SMC5 SMC5 SMARCA2 SMARCA2 ABCG5 ABCG5 KIF21A KIF21A CCT8 CCT8 WRN WRN SPAST SPAST RAD54L2 RAD54L2 ATP13A3 ATP13A3 KATNAL1 KATNAL1 MCM6 MCM6 ATP7B ATP7B VWA8 VWA8 RFC4 RFC4 HSP90AA1 HSP90AA1 ATAD2B ATAD2B PSMC1 PSMC1 TDRD9 TDRD9 DHX30 DHX30 SMC4 SMC4 ATP11B ATP11B CCT2 CCT2 CHD4 CHD4 ATP5B ATP5B ATP11A ATP11A MLH3 MLH3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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DDX4Probable ATP-dependent RNA helicase DDX4; Belongs to the DEAD box helicase family. (728 aa)
DDX47Probable ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (455 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (863 aa)
NVLNuclear valosin-containing protein-like isoform X1. (856 aa)
TOR1BTorsin. (335 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
KIF12Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (684 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (929 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
HSPA14Heat shock 70 kDa protein 14 isoform X1. (789 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
MYO1EUnconventional myosin-Ie isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
ATP7ACopper-transporting ATPase 1. (1525 aa)
TOR2ATorsin. (321 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (655 aa)
HSPA13Heat shock 70 kDa protein 13. (471 aa)
CUNH9orf84Uncharacterized protein C9orf84 homolog. (1504 aa)
TOR4Atorsin-4A. (416 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (670 aa)
KIF23LOW QUALITY PROTEIN: kinesin-like protein KIF23; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
YME1L1ATP-dependent zinc metalloprotease YME1L1. (715 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
PEX6Peroxisome biogenesis factor 6. (980 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (955 aa)
ATF7IPActivating transcription factor 7-interacting protein 1 isoform X1. (1272 aa)
TOR1Atorsin-1A. (416 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
CLPXATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1. (633 aa)
CEP41Centrosomal protein of 41 kDa isoform X1. (374 aa)
TRIP13Pachytene checkpoint protein 2 homolog; Belongs to the AAA ATPase family. (432 aa)
DHX38pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 isoform X1. (1250 aa)
VPS4AVacuolar protein sorting-associated protein 4A isoform X1; Belongs to the AAA ATPase family. (437 aa)
LOC111179605LOW QUALITY PROTEIN: ras GTPase-activating protein-binding protein 1-like. (470 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (444 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (823 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
HSP90AB1Heat shock protein HSP 90-beta. (724 aa)
MOV10Putative helicase MOV-10 isoform X1. (1001 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1251 aa)
PFN2Profilin; Belongs to the profilin family. (197 aa)
DHX36ATP-dependent RNA helicase DHX36 isoform X1. (1020 aa)
KIF6Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (794 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
SMARCAD1annotation not available (1028 aa)
CHD1Lchromodomain-helicase-DNA-binding protein 1-like isoform X1. (898 aa)
SPG7Paraplegin. (817 aa)
DDX19BATP-dependent RNA helicase DDX19B isoform X2. (479 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
ATP8B4Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1222 aa)
RFC2Replication factor C subunit 2. (352 aa)
WRNIP1ATPase WRNIP1 isoform X1. (638 aa)
SRCAPHelicase SRCAP isoform X1. (3238 aa)
INO80DNA helicase INO80 isoform X1. (1563 aa)
CCT6AT-complex protein 1 subunit zeta. (531 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2590 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (673 aa)
PMS2Mismatch repair endonuclease PMS2 isoform X4. (894 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
DHX34Probable ATP-dependent RNA helicase DHX34 isoform X1. (1145 aa)
UPK3BUroplakin-3b. (279 aa)
RAD50DNA repair protein RAD50 isoform X1. (1344 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
PEX1Peroxisome biogenesis factor 1 isoform X1. (1283 aa)
G3BP1Ras GTPase-activating protein-binding protein 1 isoform X2. (504 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
KIF13ALOW QUALITY PROTEIN: kinesin-like protein KIF13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1805 aa)
HSPA9Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa)
NSFVesicle-fusing ATPase isoform X1. (777 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1 isoform X1. (767 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
CARNS1Carnosine synthase 1 isoform X1. (1034 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit isoform X1. (782 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1. (1097 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1006 aa)
IGHMBP2DNA-binding protein SMUBP-2 isoform X1. (982 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (990 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
KIF19Kinesin-like protein KIF19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1001 aa)
FIGNL1Fidgetin-like protein 1; Belongs to the AAA ATPase family. (677 aa)
DHX9ATP-dependent RNA helicase A isoform X1. (1253 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ATP10BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1483 aa)
CHD1chromodomain-helicase-DNA-binding protein 1 isoform X1. (1798 aa)
CHD6chromodomain-helicase-DNA-binding protein 6. (2720 aa)
RHOBTB3Rho-related BTB domain-containing protein 3 isoform X1. (611 aa)
KIF13BKinesin-like protein KIF13B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1897 aa)
DDX56Probable ATP-dependent RNA helicase DDX56 isoform X1. (546 aa)
CHD7chromodomain-helicase-DNA-binding protein 7 isoform X1. (3050 aa)
MARVELD2MARVEL domain-containing protein 2 isoform X2. (559 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1057 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
KIF16BKinesin-like protein KIF16B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1328 aa)
LOC111186011Myosin-3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
CHTF18Chromosome transmission fidelity protein 18 homolog. (1006 aa)
TRAP1Heat shock protein 75 kDa, mitochondrial. (806 aa)
LOC111187281Kinesin-like protein KIF1B. (368 aa)
CCT4T-complex protein 1 subunit delta. (539 aa)
CHD2chromodomain-helicase-DNA-binding protein 2 isoform X1. (1862 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1355 aa)
DHX29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1364 aa)
DDX27Probable ATP-dependent RNA helicase DDX27 isoform X1; Belongs to the DEAD box helicase family. (770 aa)
CHD3chromodomain-helicase-DNA-binding protein 3 isoform X1. (2155 aa)
EIF4A1Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family. (406 aa)
ATAD5ATPase family AAA domain-containing protein 5 isoform X1. (1898 aa)
KIF1CKinesin-like protein KIF1C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1102 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
SPATA5Spermatogenesis-associated protein 5 isoform X1. (887 aa)
CHD5chromodomain-helicase-DNA-binding protein 5 isoform X1. (1954 aa)
SMC1BStructural maintenance of chromosomes protein. (1240 aa)
SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa)
ATP9APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1047 aa)
DDX55RNA helicase. (599 aa)
RFC5Replication factor C subunit 5. (340 aa)
SMC2Structural maintenance of chromosomes protein. (1191 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
LOC111188071Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1167 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (966 aa)
LOC111187147ATPase family AAA domain-containing protein 3 isoform X1. (586 aa)
LOC111187138Kinesin-like protein KIF1B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1816 aa)
ATP10APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1498 aa)
HSP90B1Endoplasmin. (805 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (806 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (876 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (2000 aa)
DDX52Probable ATP-dependent RNA helicase DDX52. (598 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (683 aa)
MYO19Unconventional myosin-XIX isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (958 aa)
ALPLAlkaline phosphatase. (550 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5597 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
ATAD2ATPase family AAA domain-containing protein 2 isoform X1. (1390 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
RECQL4LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q4. (1211 aa)
CUNH17orf64Uncharacterized protein C17orf64 homolog. (262 aa)
CHD9chromodomain-helicase-DNA-binding protein 9 isoform X1. (2902 aa)
MORC3MORC family CW-type zinc finger protein 3 isoform X1. (938 aa)
MORC2MORC family CW-type zinc finger protein 2 isoform X1. (1064 aa)
ABCD3ATP-binding cassette sub-family D member 3 isoform X1. (656 aa)
ABCA4Retinal-specific ATP-binding cassette transporter. (2205 aa)
DNAH6Dynein heavy chain 6, axonemal. (4154 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (837 aa)
AFG1LAFG1-like ATPase isoform X1. (523 aa)
DDX25ATP-dependent RNA helicase DDX25. (483 aa)
MCM8DNA helicase MCM8; Belongs to the MCM family. (832 aa)
ATP11CPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1129 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
ABCB10ATP-binding cassette sub-family B member 10, mitochondrial. (731 aa)
NTPCRCancer-related nucleoside-triphosphatase isoform X1. (190 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2201 aa)
MCM9DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1144 aa)
SMARCA4Transcription activator BRG1 isoform X4. (1648 aa)
MLH1DNA mismatch repair protein Mlh1 isoform X1. (758 aa)
KIF15Kinesin-like protein KIF15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1327 aa)
DDX1ATP-dependent RNA helicase DDX1. (740 aa)
ATP13A1Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1205 aa)
MCM4DNA helicase; Belongs to the MCM family. (836 aa)
LOC111166987Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
TMEM59LTransmembrane protein 59-like isoform X1. (350 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
NAV3Neuron navigator 3 isoform X1. (2299 aa)
LOC111166986Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
TCP1T-complex protein 1 subunit alpha. (556 aa)
ABCG4ATP-binding cassette sub-family G member 4 isoform X1. (646 aa)
UPF1Regulator of nonsense transcripts 1 isoform X1. (1127 aa)
DDX39AATP-dependent RNA helicase DDX39A. (427 aa)
TOR3Atorsin-3A isoform X1. (401 aa)
ERMARDEndoplasmic reticulum membrane-associated RNA degradation protein isoform X1. (687 aa)
ATP8B3LOW QUALITY PROTEIN: phospholipid-transporting ATPase IK. (808 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
ATP8B2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1296 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (543 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1320 aa)
DHX58Probable ATP-dependent RNA helicase DHX58 isoform X1. (680 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (477 aa)
ASNA1ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa)
DQX1ATP-dependent RNA helicase DQX1. (719 aa)
KIF7Kinesin-like protein KIF7 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1371 aa)
ATP10DPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1346 aa)
ATP9BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1134 aa)
DDX39BSpliceosome RNA helicase DDX39B. (428 aa)
LOC111170664Heat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa)
LOC111170662Heat shock 70 kDa protein 1B; Belongs to the heat shock protein 70 family. (641 aa)
ATP8A1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1164 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (866 aa)
CCT6BLOW QUALITY PROTEIN: T-complex protein 1 subunit zeta-2. (213 aa)
ERCC6LDNA excision repair protein ERCC-6-like. (1249 aa)
LOC111171193Uncharacterized protein C10orf88-like. (209 aa)
KIF21BKinesin-like protein KIF21B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1668 aa)
ABCD1ATP-binding cassette sub-family D member 1 isoform X1. (774 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
IQCA1IQ and AAA domain-containing protein 1. (831 aa)
KIF1AKinesin-like protein KIF1A isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1819 aa)
CUNH10orf88Uncharacterized protein C10orf88 homolog. (445 aa)
ATP13A4Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (965 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
ATAD1ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (404 aa)
MORC4MORC family CW-type zinc finger protein 4 isoform X1. (936 aa)
IFIH1Interferon-induced helicase C domain-containing protein 1. (1023 aa)
LOC111172806Fidgetin-like isoform X1; Belongs to the AAA ATPase family. (759 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PMS1PMS1 protein homolog 1 isoform X1. (932 aa)
HSPA6LOW QUALITY PROTEIN: heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family. (645 aa)
BTAF1TATA-binding protein-associated factor 172 isoform X1. (1849 aa)
CLPBCaseinolytic peptidase B protein homolog isoform X1. (677 aa)
RFC1Replication factor C subunit 1. (1146 aa)
LOC111171833Mitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (419 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1248 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
EIF4A2Eukaryotic initiation factor 4A-II isoform X1; Belongs to the DEAD box helicase family. (408 aa)
TM4SF19Transmembrane 4 L6 family member 19. (202 aa)
KIF5AKinesin heavy chain isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
LOC111171395Cation-transporting ATPase 13A2-like. (209 aa)
FIGNL2Putative fidgetin-like protein 2. (656 aa)
ABCD2ATP-binding cassette sub-family D member 2. (741 aa)
ABCB6ATP-binding cassette sub-family B member 6, mitochondrial. (844 aa)
LOC111172805Fidgetin; Belongs to the AAA ATPase family. (748 aa)
OLA1Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (396 aa)
SMC5Structural maintenance of chromosomes protein 5 isoform X1. (1106 aa)
SMARCA2Probable global transcription activator SNF2L2 isoform X1. (1597 aa)
ABCG5LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5. (652 aa)
KIF21AKinesin-like protein KIF21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1673 aa)
CCT8T-complex protein 1 subunit theta. (548 aa)
WRNWerner syndrome ATP-dependent helicase isoform X1. (1454 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
RAD54L2Helicase ARIP4 isoform X1. (1465 aa)
ATP13A3Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1259 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
ATP7BCopper-transporting ATPase 2 isoform X1. (1523 aa)
VWA8Von Willebrand factor A domain-containing protein 8 isoform X1. (1905 aa)
RFC4Replication factor C subunit 4. (364 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
ATAD2BATPase family AAA domain-containing protein 2B isoform X1. (1458 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
TDRD9Putative ATP-dependent RNA helicase TDRD9 isoform X1. (1286 aa)
DHX30Putative ATP-dependent RNA helicase DHX30 isoform X1. (1222 aa)
SMC4Structural maintenance of chromosomes protein. (1288 aa)
ATP11BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1177 aa)
CCT2T-complex protein 1 subunit beta. (535 aa)
CHD4chromodomain-helicase-DNA-binding protein 4 isoform X1. (1940 aa)
ATP5BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
ATP11APhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (987 aa)
MLH3DNA mismatch repair protein Mlh3 isoform X1. (1455 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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