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LOC111179403 LOC111179403 GUCY1A3 GUCY1A3 LOC111179579 LOC111179579 TBXAS1 TBXAS1 CAT CAT LOC111177811 LOC111177811 CUNH1orf194 CUNH1orf194 LOC111177818 LOC111177818 LOC111180074 LOC111180074 TDO2 TDO2 LOC111180830 LOC111180830 LOC111178887 LOC111178887 GUCY1B3 GUCY1B3 LOC111181936 LOC111181936 LOC111180543 LOC111180543 EIF2AK1 EIF2AK1 LOC111181555 LOC111181555 STEAP4 STEAP4 CCNDBP1 CCNDBP1 B3GNT8 B3GNT8 LOC111180826 LOC111180826 LOC111182289 LOC111182289 LOC111180832 LOC111180832 CYGB CYGB LOC111183193 LOC111183193 SRC SRC HBZ HBZ HMOX2 HMOX2 FADS1 FADS1 HBM HBM HBQ1 HBQ1 LOC111185089 LOC111185089 PTGS2 PTGS2 LOC111170860 LOC111170860 IDO2 IDO2 LOC111173600 LOC111173600 SUOX SUOX LOC111172487 LOC111172487 ABCB6 ABCB6 LOC111174575 LOC111174575 LOC111172488 LOC111172488 LOC111175420 LOC111175420 LOC111172911 LOC111172911 SLC48A1 SLC48A1 LOC111175878 LOC111175878 MB MB HMOX1 HMOX1 NOS1 NOS1 STC2 STC2 LOC111186231 LOC111186231 LOC111185989 LOC111185989 LOC111186695 LOC111186695 PTGIS PTGIS FLVCR1 FLVCR1 LOC111185591 LOC111185591 LOC111167287 LOC111167287 LOC111166705 LOC111166705 LOC111169165 LOC111169165 LOC111172152 LOC111172152 LOC111169219 LOC111169219 LOC111171487 LOC111171487 LOC111171752 LOC111171752 LOC111172397 LOC111172397 LOC111170705 LOC111170705 THAP4 THAP4 LOC111171257 LOC111171257 LOC111171230 LOC111171230 XK XK LOC111169375 LOC111169375 LOC111171015 LOC111171015 LOC111170861 LOC111170861 PXDN PXDN PGRMC1 PGRMC1 ADGB ADGB LOC111167219 LOC111167219 HEBP2 HEBP2 SDHD SDHD LOC111167902 LOC111167902 LOC111171052 LOC111171052 LOC111171379 LOC111171379 LOC111172355 LOC111172355 LOC111170450 LOC111170450 LOC111171838 LOC111171838 TTI2 TTI2 SDHC SDHC RSAD1 RSAD1 NR1D1 NR1D1 LOC111166611 LOC111166611 LOC111166561 LOC111166561 LOC111165123 LOC111165123 LOC111165107 LOC111165107 LOC111165853 LOC111165853 LPO LPO CBS CBS LOC111173427 LOC111173427 CCDC160 CCDC160 MPO MPO LOC111164311 LOC111164311 EPX EPX DGCR8 DGCR8 COX1 COX1 HBB HBB PGRMC2 PGRMC2 GUCY1A2 GUCY1A2 TPO TPO LOC111165268 LOC111165268 IDO1 IDO1 LOC111174599 LOC111174599 NGB NGB FLVCR2 FLVCR2 LOC111174870 LOC111174870 NOS3 NOS3 LOC111174031 LOC111174031 LOC111176091 LOC111176091 LOC111174197 LOC111174197 LOC111174356 LOC111174356 PTGS1 PTGS1 LOC111175930 LOC111175930 PTGES2 PTGES2 AMBP AMBP HEBP1 HEBP1 LOC111177607 LOC111177607 BTBD6 BTBD6
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC111179403Cytochrome b-245 light chain isoform X1. (202 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
LOC111179579Cytochrome b5 type B; Belongs to the cytochrome b5 family. (146 aa)
TBXAS1thromboxane-A synthase isoform X1; Belongs to the cytochrome P450 family. (585 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
LOC111177811Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (520 aa)
CUNH1orf194Uncharacterized protein C1orf194 homolog isoform X1. (170 aa)
LOC111177818Cytochrome P450 1A1 isoform X1; Belongs to the cytochrome P450 family. (516 aa)
LOC111180074Cytochrome b561 domain-containing protein 1 isoform X1. (229 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
LOC111180830Cytochrome P450 2S1-like isoform X1; Belongs to the cytochrome P450 family. (494 aa)
LOC11117888724-hydroxycholesterol 7-alpha-hydroxylase; Belongs to the cytochrome P450 family. (469 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
LOC111181936Cytochrome P450 3A29-like. (415 aa)
LOC111180543Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
EIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (623 aa)
LOC111181555Dual oxidase 2 isoform X2. (1611 aa)
STEAP4Metalloreductase STEAP4 isoform X1. (469 aa)
CCNDBP1cyclin-D1-binding protein 1. (358 aa)
B3GNT8Hexosyltransferase. (397 aa)
LOC111180826Lanosterol 14-alpha demethylase isoform X1; Belongs to the cytochrome P450 family. (503 aa)
LOC111182289LOW QUALITY PROTEIN: uroplakin-3b-like protein 1. (253 aa)
LOC111180832Cytochrome P450 2F5-like. (80 aa)
CYGBCytoglobin; Belongs to the globin family. (190 aa)
LOC111183193Cytochrome b5 reductase 4 isoform X1. (484 aa)
SRCTyrosine-protein kinase. (562 aa)
HBZHemoglobin subunit zeta; Belongs to the globin family. (142 aa)
HMOX2Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (316 aa)
FADS1Fatty acid desaturase 1. (440 aa)
HBMHemoglobin subunit mu; Belongs to the globin family. (141 aa)
HBQ1Hemoglobin subunit theta-1-like; Belongs to the globin family. (142 aa)
LOC111185089Hemoglobin subunit alpha; Belongs to the globin family. (142 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
LOC111170860Aromatase; Belongs to the cytochrome P450 family. (503 aa)
IDO2Indoleamine 2,3-dioxygenase 2 isoform X1. (469 aa)
LOC111173600Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
SUOXSulfite oxidase, mitochondrial isoform X1. (552 aa)
LOC111172487Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (497 aa)
ABCB6ATP-binding cassette sub-family B member 6, mitochondrial. (844 aa)
LOC111174575Cytochrome c-like. (69 aa)
LOC111172488Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (523 aa)
LOC111175420LOW QUALITY PROTEIN: cytochrome P450 4B1; Belongs to the cytochrome P450 family. (503 aa)
LOC111172911Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
SLC48A1Heme transporter HRG1. (146 aa)
LOC111175878Cytochrome P450 2J2 isoform X1; Belongs to the cytochrome P450 family. (502 aa)
MBMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
NOS1Nitric oxide synthase, brain isoform X1. (1461 aa)
STC2Stanniocalcin-2. (302 aa)
LOC111186231LOW QUALITY PROTEIN: cytochrome P450 2D14; Belongs to the cytochrome P450 family. (515 aa)
LOC111185989Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa)
LOC1111866951,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (514 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1 isoform X1. (555 aa)
LOC11118559125-hydroxycholesterol 7-alpha-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (502 aa)
LOC111167287Cytochrome b5; Belongs to the cytochrome b5 family. (134 aa)
LOC111166705Phylloquinone omega-hydroxylase CYP4F2-like isoform X1; Belongs to the cytochrome P450 family. (524 aa)
LOC111169165Hemoglobin subunit epsilon-2-like; Belongs to the globin family. (133 aa)
LOC111172152Cytochrome P450 2E1 isoform X1; Belongs to the cytochrome P450 family. (495 aa)
LOC111169219Hemoglobin subunit beta-Z isoform X1; Belongs to the globin family. (151 aa)
LOC111171487Cytochrome P450 2U1 isoform X1; Belongs to the cytochrome P450 family. (543 aa)
LOC111171752Cytochrome P450 20A1 isoform X1. (462 aa)
LOC111172397Cytochrome P450 2C23-like; Belongs to the cytochrome P450 family. (504 aa)
LOC111170705Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (495 aa)
THAP4THAP domain-containing protein 4 isoform X1. (585 aa)
LOC111171257LOW QUALITY PROTEIN: docosahexaenoic acid omega-hydroxylase CYP4F3-like. (145 aa)
LOC111171230Cytochrome P450 3A5-like. (115 aa)
XKXK-related protein. (444 aa)
LOC111169375LOW QUALITY PROTEIN: cytochrome P450 2W1; Belongs to the cytochrome P450 family. (510 aa)
LOC111171015Aromatase-like; Belongs to the cytochrome P450 family. (296 aa)
LOC111170861Aromatase-like. (388 aa)
PXDNPeroxidasin homolog isoform X3. (1478 aa)
PGRMC1Membrane-associated progesterone receptor component 1; Belongs to the cytochrome b5 family. (194 aa)
ADGBAndroglobin; Belongs to the peptidase C2 family. (1633 aa)
LOC111167219Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (269 aa)
HEBP2Heme-binding protein 2. (204 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
LOC111167902Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
LOC111171052Cytochrome b5 reductase 4-like. (137 aa)
LOC111171379Cytochrome P450 4A4-like isoform X1. (181 aa)
LOC111172355Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family. (509 aa)
LOC111170450Cytochrome b-245 heavy chain isoform X1. (570 aa)
LOC111171838Sterol 26-hydroxylase, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (571 aa)
TTI2TELO2-interacting protein 2. (508 aa)
SDHCSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial. (169 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (547 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
LOC111166611Cytochrome P450 4F22; Belongs to the cytochrome P450 family. (567 aa)
LOC111166561LOW QUALITY PROTEIN: docosahexaenoic acid omega-hydroxylase CYP4F3-like. (215 aa)
LOC111165123Cytochrome c1, heme protein, mitochondrial. (326 aa)
LOC111165107Cytochrome P450 11B1, mitochondrial isoform X1; Belongs to the cytochrome P450 family. (503 aa)
LOC111165853Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
LPOLactoperoxidase isoform X2. (712 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (562 aa)
LOC111173427Cytochrome P450 4V2; Belongs to the cytochrome P450 family. (652 aa)
CCDC160Coiled-coil domain-containing protein 160. (325 aa)
MPOMyeloperoxidase. (719 aa)
LOC1111643115-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; Belongs to the cytochrome P450 family. (511 aa)
EPXEosinophil peroxidase. (715 aa)
DGCR8Microprocessor complex subunit DGCR8 isoform X1. (773 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (516 aa)
HBBHemoglobin subunit beta; Belongs to the globin family. (147 aa)
PGRMC2LOW QUALITY PROTEIN: membrane-associated progesterone receptor component 2; Belongs to the cytochrome b5 family. (247 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (726 aa)
TPOThyroid peroxidase. (870 aa)
LOC111165268Vitamin D 25-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa)
IDO1Indoleamine 2,3-dioxygenase 1 isoform X1. (410 aa)
LOC111174599Cytochrome P450 1A1-like. (104 aa)
NGBNeuroglobin isoform X1; Belongs to the globin family. (205 aa)
FLVCR2Feline leukemia virus subgroup C receptor-related protein 2 isoform X1. (525 aa)
LOC111174870Cytochrome P450 1B1; Belongs to the cytochrome P450 family. (543 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
LOC111174031Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC111176091Cholesterol 24-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (501 aa)
LOC111174197Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
LOC111174356Cytochrome b561 domain-containing protein 2. (222 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (600 aa)
LOC111175930Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PTGES2Prostaglandin E synthase 2 isoform X1. (372 aa)
AMBPProtein AMBP. (352 aa)
HEBP1Heme-binding protein 1. (191 aa)
LOC111177607Cytochrome P450 1A2; Belongs to the cytochrome P450 family. (516 aa)
BTBD6BTB/POZ domain-containing protein 6. (538 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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