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| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | Ob | Leptin isoform X1. (167 aa) |
| | SHB | SH2 domain-containing adapter protein B. (507 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (180 aa) |
| | IL1RL2 | Interleukin-1 receptor-like 2 isoform X1. (570 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3 isoform X1. (641 aa) |
| | IGF1 | Insulin-like growth factor I isoform X1. (186 aa) |
| | FGG | Fibrinogen gamma chain isoform X1. (445 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X1. (687 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | NCK2 | Cytoplasmic protein. (376 aa) |
| | ITGB2 | Integrin beta. (769 aa) |
| | LOC111187428 | Interleukin-1. (118 aa) |
| | HHLA2 | HERV-H LTR-associating protein 2 isoform X1. (414 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (146 aa) |
| | PIK3R6 | Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa) |
| | FGB | Fibrinogen beta chain isoform X1. (495 aa) |
| | IL7R | Interleukin-7 receptor subunit alpha isoform X1. (459 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa) |
| | LOC111187417 | Tyrosine-protein kinase. (612 aa) |
| | IL6ST | Interleukin-6 receptor subunit beta. (918 aa) |
| | PDPN | Podoplanin isoform X1. (235 aa) |
| | TNFRSF13C | Tumor necrosis factor receptor superfamily member 13C isoform X1. (221 aa) |
| | NFKBIZ | NF-kappa-B inhibitor zeta. (726 aa) |
| | SOX13 | Transcription factor SOX-13. (644 aa) |
| | GLI3 | Transcriptional activator GLI3 isoform X1. (1587 aa) |
| | SOX12 | Transcription factor SOX. (312 aa) |
| | SIRPA | Tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1. (504 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa) |
| | ADA | Adenosine deaminase isoform X1. (416 aa) |
| | EFNB3 | ephrin-B3 isoform X1; Belongs to the ephrin family. (340 aa) |
| | CD47 | Leukocyte surface antigen CD47 isoform X1. (329 aa) |
| | CD5 | T-cell surface glycoprotein CD5 isoform X1. (500 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | CCDC88B | Coiled-coil domain-containing protein 88B isoform X1. (1463 aa) |
| | CD6 | T-cell differentiation antigen CD6 isoform X1. (675 aa) |
| | ZMIZ1 | Zinc finger MIZ domain-containing protein 1 isoform X1. (1071 aa) |
| | VSIR | V-type immunoglobulin domain-containing suppressor of T-cell activation. (311 aa) |
| | RPS3 | 40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | SART1 | U4/U6.U5 tri-snRNP-associated protein 1. (803 aa) |
| | LOC111184361 | Signal-regulatory protein beta-1-like isoform X1. (412 aa) |
| | MEGF10 | Multiple epidermal growth factor-like domains protein 10. (1139 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | IGF2 | Insulin-like growth factor II isoform X3. (237 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | AMBRA1 | Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1295 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (166 aa) |
| | LOC111181354 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase-like. (321 aa) |
| | ZP3 | Zona pellucida sperm-binding protein 3. (421 aa) |
| | ADAM19 | Disintegrin and metalloproteinase domain-containing protein 19. (909 aa) |
| | RASGRP1 | RAS guanyl-releasing protein 1 isoform X1. (870 aa) |
| | PLAUR | Urokinase plasminogen activator surface receptor isoform X1. (331 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | PTPN22 | Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (801 aa) |
| | GCNT2 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase isoform X1. (419 aa) |
| | PYCARD | Apoptosis-associated speck-like protein containing a CARD. (195 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | RNASE10 | Inactive ribonuclease-like protein 10; Belongs to the pancreatic ribonuclease family. (212 aa) |
| | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa) |
| | CD83 | CD83 antigen isoform X1. (195 aa) |
| | CD44 | CD44 antigen isoform X1. (742 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | LOC111178927 | HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa) |
| | IL4I1 | L-amino-acid oxidase isoform X1. (653 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | BTNL2 | Butyrophilin-like protein 2. (454 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | MMRN1 | Multimerin-1. (1216 aa) |
| | IL23R | Interleukin-23 receptor. (630 aa) |
| | BCL10 | B-cell lymphoma/leukemia 10. (233 aa) |
| | LOC111178666 | HLA class II histocompatibility antigen, DM alpha chain isoform X1; Belongs to the MHC class II family. (261 aa) |
| | GATA3 | Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa) |
| | IL12RB2 | Interleukin-12 receptor subunit beta-2 isoform X1. (861 aa) |
| | PODXL | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (532 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | CHST2 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (530 aa) |
| | KIF26B | Kinesin-like protein KIF26B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2113 aa) |
| | EPHB6 | Ephrin type-B receptor 6 isoform X1. (1010 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | FUT7 | Alpha-(1,3)-fucosyltransferase 7. (342 aa) |
| | LOC111176900 | GTPase IMAP family member 5-like isoform X1. (332 aa) |
| | LOC111176792 | LOW QUALITY PROTEIN: hyaluronan synthase 2-like. (318 aa) |
| | LOC111178929 | HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa) |
| | LOC111178925 | boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | LOC111178668 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) |
| | PRKCQ | Protein kinase C. (665 aa) |
| | LOC111178931 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa) |
| | LOC111178928 | DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa) |
| | LOC111178664 | HLA class II histocompatibility antigen, DM beta chain isoform X1. (263 aa) |
| | HLX | H2.0-like homeobox protein. (488 aa) |
| | LCK | Tyrosine-protein kinase. (509 aa) |
| | TNFSF13B | Tumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (283 aa) |
| | BMI1 | Polycomb complex protein BMI-1. (326 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa) |
| | DOCK8 | Dedicator of cytokinesis protein 8 isoform X1; Belongs to the DOCK family. (2098 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | DENND6A | Protein DENND6A isoform X1. (608 aa) |
| | CD27 | CD27 antigen isoform X1. (251 aa) |
| | MAGI1 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X1. (1484 aa) |
| | PLPP3 | Phospholipid phosphatase 3. (312 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2 isoform X1. (337 aa) |
| | LOC111175407 | Amine oxidase. (524 aa) |
| | GCNT1 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase isoform X1. (485 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | CD274 | Programmed cell death 1 ligand 1 isoform X2. (312 aa) |
| | SLC7A1 | High affinity cationic amino acid transporter 1. (629 aa) |
| | PTPN23 | Tyrosine-protein phosphatase non-receptor type 23 isoform X1. (1630 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | ADAM8 | Disintegrin and metalloproteinase domain-containing protein 8 isoform X1. (838 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | HES1 | Transcription factor HES-1. (280 aa) |
| | NCKAP1L | Nck-associated protein 1-like isoform X1. (1156 aa) |
| | ZBTB1 | Zinc finger and BTB domain-containing protein 1. (713 aa) |
| | TFRC | Transferrin receptor protein 1 isoform X1. (772 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa) |
| | IGFBP2 | Insulin-like growth factor-binding protein 2 isoform X1. (320 aa) |
| | RHOH | Rho-related GTP-binding protein RhoH. (191 aa) |
| | HSPD1 | 60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | DPP4 | Dipeptidyl peptidase 4 isoform X1; Belongs to the peptidase S9B family. (804 aa) |
| | BCL6 | B-cell lymphoma 6 protein. (706 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (877 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28. (265 aa) |
| | TNFSF4 | Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa) |
| | DMTN | Dematin isoform X1. (405 aa) |
| | ICOS | Inducible T-cell costimulator isoform X1. (227 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | FSTL3 | Follistatin-related protein 3. (262 aa) |
| | CD86 | T-lymphocyte activation antigen CD86 isoform X1. (344 aa) |
| | AGER | Advanced glycosylation end product-specific receptor isoform X1. (631 aa) |
| | CARD11 | Caspase recruitment domain-containing protein 11 isoform X1. (1154 aa) |
| | AIF1 | Allograft inflammatory factor 1 isoform X1. (162 aa) |
| | FUT4 | Alpha-(1,3)-fucosyltransferase 4. (458 aa) |
| | LOC111169054 | NF-kappa-B-activating protein. (417 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | LOC111167809 | ephrin-B1 isoform X1; Belongs to the ephrin family. (346 aa) |
| | IL2RG | Cytokine receptor common subunit gamma isoform X1. (381 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | CD80 | T-lymphocyte activation antigen CD80 isoform X1. (295 aa) |
| | THY1 | Thy-1 membrane glycoprotein. (161 aa) |
| | FOXP3 | Forkhead box protein P3. (431 aa) |
| | F11R | Junctional adhesion molecule A. (299 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | SELE | E-selectin. (531 aa) |
| | SELP | P-selectin isoform X1. (768 aa) |
| | EGR3 | Early growth response protein 3 isoform X1. (387 aa) |
| | CITED2 | Cbp/p300-interacting transactivator 2. (272 aa) |
| | SPTA1 | Spectrin alpha chain, erythrocytic 1 isoform X1. (2417 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule isoform X1. (378 aa) |
| | ZBTB7B | Zinc finger and BTB domain-containing protein 7B. (541 aa) |
| | TNFSF9 | Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (252 aa) |
| | PTPRC | Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa) |
| | ZBTB16 | Zinc finger and BTB domain-containing protein 16. (673 aa) |
| | SASH3 | SAM and SH3 domain-containing protein 3. (380 aa) |
| | KIFAP3 | Kinesin-associated protein 3 isoform X1. (793 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | TMIGD2 | Transmembrane and immunoglobulin domain-containing protein 2. (231 aa) |
| | PAWR | PRKC apoptosis WT1 regulator protein. (345 aa) |
| | IL7 | Interleukin-7 isoform X1. (226 aa) |
| | RASAL3 | RAS protein activator like-3 isoform X1. (1035 aa) |
| | IL12RB1 | Interleukin-12 receptor subunit beta-1 isoform X1. (726 aa) |
| | IL27RA | Interleukin-27 receptor subunit alpha isoform X1. (656 aa) |
| | ST3GAL4 | CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 4 isoform X4; Belongs to the glycosyltransferase 29 family. (341 aa) |
| | FCHO1 | F-BAR domain only protein 1. (887 aa) |
| | DHPS | Deoxyhypusine synthase. (369 aa) |
| | CCR7 | C-C chemokine receptor type 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | LOC111166071 | Phospholipid phosphatase 3-like. (264 aa) |
| | LOC111166483 | Signal transducer and activator of transcription. (787 aa) |
| | STAT5A | Signal transducer and activator of transcription. (818 aa) |
| | RARA | Retinoic acid receptor alpha isoform X5. (584 aa) |
| | TYK2 | Tyrosine-protein kinase. (1188 aa) |
| | TNFSF14 | Tumor necrosis factor ligand superfamily member 14 isoform X1. (241 aa) |
| | MYB | Transcriptional activator Myb isoform X3. (761 aa) |
| | VNN1 | Pantetheinase. (514 aa) |
| | PTPRU | Receptor-type tyrosine-protein phosphatase U isoform X1. (1452 aa) |
| | ETS1 | Protein C-ets-1 isoform X1. (486 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | HAS2 | Hyaluronan synthase 2. (552 aa) |
| | FAM49B | Protein FAM49B isoform X1. (324 aa) |
| | XBP1 | LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (215 aa) |
| | EMILIN2 | EMILIN-2. (1070 aa) |
| | CCL19 | C-C motif chemokine. (159 aa) |
| | IGLL1 | Immunoglobulin lambda-like polypeptide 1 isoform X1. (212 aa) |
