STRINGSTRING
SORBS1 SORBS1 GNB1 GNB1 PTPN11 PTPN11 LOC111187339 LOC111187339 PIK3R1 PIK3R1 SPATA2 SPATA2 SHANK3 SHANK3 MAPK8IP3 MAPK8IP3 SH2B3 SH2B3 GAB2 GAB2 LOC111186752 LOC111186752 AXIN1 AXIN1 CRK CRK SHANK2 SHANK2 GRB10 GRB10 LAT LAT SH2B2 SH2B2 GRB2 GRB2 GNB2 GNB2 SH2B1 SH2B1 NUP62 NUP62 SHANK1 SHANK1 TRADD TRADD FRS3 FRS3 GNB5 GNB5 LOC111176690 LOC111176690 GNB3 GNB3 POC1A POC1A GRIP1 GRIP1 GNB4 GNB4 SAV1 SAV1 FRS2 FRS2 DOK1 DOK1 IRS1 IRS1 LOC111171019 LOC111171019 DOK3 DOK3 DOK2 DOK2 HOMER2 HOMER2 SPAG9 SPAG9 MAGI2 MAGI2 POC1B POC1B LDLRAP1 LDLRAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SORBS1Sorbin and SH3 domain-containing protein 1 isoform X30. (1291 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC111187339LOW QUALITY PROTEIN: growth factor receptor-bound protein 10-like. (665 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
SPATA2Spermatogenesis-associated protein 2. (520 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3 isoform X1. (1733 aa)
MAPK8IP3C-Jun-amino-terminal kinase-interacting protein 3 isoform X4. (1336 aa)
SH2B3SH2B adapter protein 3 isoform X1. (618 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
LOC111186752T-cell receptor-associated transmembrane adapter 1. (185 aa)
AXIN1Axin-1 isoform X1. (866 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
SHANK2SH3 and multiple ankyrin repeat domains protein 2 isoform X1. (1901 aa)
GRB10Growth factor receptor-bound protein 10 isoform X1. (588 aa)
LATLinker for activation of T-cells family member 1 isoform X1. (270 aa)
SH2B2SH2B adapter protein 2 isoform X1. (703 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
SH2B1SH2B adapter protein 1 isoform X1. (795 aa)
NUP62Nuclear pore glycoprotein p62. (516 aa)
SHANK1SH3 and multiple ankyrin repeat domains protein 1 isoform X1. (2170 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa)
FRS3Fibroblast growth factor receptor substrate 3. (495 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (414 aa)
LOC111176690Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X2. (299 aa)
POC1APOC1 centriolar protein homolog A isoform X1. (475 aa)
GRIP1Glutamate receptor-interacting protein 1. (886 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4 isoform X1. (340 aa)
SAV1Protein salvador homolog 1. (385 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
DOK1Docking protein 1 isoform X2. (483 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
LOC111171019Glutamate receptor-interacting protein 1-like. (206 aa)
DOK3Docking protein 3. (449 aa)
DOK2Docking protein 2. (411 aa)
HOMER2Homer protein homolog 2 isoform X1. (343 aa)
SPAG9C-Jun-amino-terminal kinase-interacting protein 4 isoform X1. (1334 aa)
MAGI2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1. (1451 aa)
POC1BPOC1 centriolar protein homolog B isoform X1. (478 aa)
LDLRAP1LOW QUALITY PROTEIN: low density lipoprotein receptor adapter protein 1. (309 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.