28 items (Delphinapterus leucas) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	UBASH3B	Ubiquitin-associated and SH3 domain-containing protein B isoform X1. (649 aa)
	PLG	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
	PDGFA	Platelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (196 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
	F12	LOW QUALITY PROTEIN: coagulation factor XII. (650 aa)
	SERPINE2	Glia-derived nexin isoform X2; Belongs to the serpin family. (397 aa)
	LOC111173428	Coagulation factor XI; Belongs to the peptidase S1 family. (633 aa)
	TFPI	Tissue factor pathway inhibitor isoform X1. (307 aa)
	KNG1	Kininogen-1 isoform X1. (627 aa)
	CPB2	Carboxypeptidase B2. (423 aa)
	PRKG1	cGMP-dependent protein kinase. (686 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (733 aa)
	PROS1	Vitamin K-dependent protein S. (675 aa)
	ADAMTS18	A disintegrin and metalloproteinase with thrombospondin motifs 18 isoform X1. (1227 aa)
	ADTRP	Androgen-dependent TFPI-regulating protein isoform X1. (230 aa)
	PLAU	Urokinase-type plasminogen activator. (431 aa)
	C1QTNF1	LOW QUALITY PROTEIN: complement C1q tumor necrosis factor-related protein 1. (279 aa)
	SERPING1	Plasma protease C1 inhibitor; Belongs to the serpin family. (471 aa)
	APOH	Beta-2-glycoprotein 1 isoform X1. (345 aa)
	PROC	Vitamin K-dependent protein C. (480 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
	PDGFB	Platelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (278 aa)
	SH2B3	SH2B adapter protein 3 isoform X1. (618 aa)
	THBD	Thrombomodulin. (584 aa)
	FGB	Fibrinogen beta chain isoform X1. (495 aa)
	C1QTNF6	Complement C1q tumor necrosis factor-related protein 6. (266 aa)
	FGG	Fibrinogen gamma chain isoform X1. (445 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOH	F12	A0A2Y9PRN3	A0A2Y9MGJ8	Beta-2-glycoprotein 1 isoform X1.	LOW QUALITY PROTEIN: coagulation factor XII.	0.430
APOH	F2	A0A2Y9PRN3	A0A2Y9PXE8	Beta-2-glycoprotein 1 isoform X1.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.895
APOH	FGB	A0A2Y9PRN3	A0A2Y9Q8K0	Beta-2-glycoprotein 1 isoform X1.	Fibrinogen beta chain isoform X1.	0.771
APOH	FGG	A0A2Y9PRN3	A0A2Y9QCX0	Beta-2-glycoprotein 1 isoform X1.	Fibrinogen gamma chain isoform X1.	0.832
APOH	PLG	A0A2Y9PRN3	A0A2Y9M5R2	Beta-2-glycoprotein 1 isoform X1.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.781
APOH	PROC	A0A2Y9PRN3	A0A2Y9PTI6	Beta-2-glycoprotein 1 isoform X1.	Vitamin K-dependent protein C.	0.537
APOH	SERPINE2	A0A2Y9PRN3	A0A2Y9MNF5	Beta-2-glycoprotein 1 isoform X1.	Glia-derived nexin isoform X2; Belongs to the serpin family.	0.521
CPB2	F2	A0A2Y9N763	A0A2Y9PXE8	Carboxypeptidase B2.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.959
CPB2	FGG	A0A2Y9N763	A0A2Y9QCX0	Carboxypeptidase B2.	Fibrinogen gamma chain isoform X1.	0.452
CPB2	LOC111173428	A0A2Y9N763	A0A2Y9MXX5	Carboxypeptidase B2.	Coagulation factor XI; Belongs to the peptidase S1 family.	0.492
CPB2	PLG	A0A2Y9N763	A0A2Y9M5R2	Carboxypeptidase B2.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.566
CPB2	PROC	A0A2Y9N763	A0A2Y9PTI6	Carboxypeptidase B2.	Vitamin K-dependent protein C.	0.503
CPB2	THBD	A0A2Y9N763	A0A2Y9Q3F5	Carboxypeptidase B2.	Thrombomodulin.	0.436
F12	APOH	A0A2Y9MGJ8	A0A2Y9PRN3	LOW QUALITY PROTEIN: coagulation factor XII.	Beta-2-glycoprotein 1 isoform X1.	0.430
F12	F2	A0A2Y9MGJ8	A0A2Y9PXE8	LOW QUALITY PROTEIN: coagulation factor XII.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.581
F12	FGB	A0A2Y9MGJ8	A0A2Y9Q8K0	LOW QUALITY PROTEIN: coagulation factor XII.	Fibrinogen beta chain isoform X1.	0.445
F12	FGG	A0A2Y9MGJ8	A0A2Y9QCX0	LOW QUALITY PROTEIN: coagulation factor XII.	Fibrinogen gamma chain isoform X1.	0.451
F12	KNG1	A0A2Y9MGJ8	A0A2Y9N2V9	LOW QUALITY PROTEIN: coagulation factor XII.	Kininogen-1 isoform X1.	0.830
F12	LOC111173428	A0A2Y9MGJ8	A0A2Y9MXX5	LOW QUALITY PROTEIN: coagulation factor XII.	Coagulation factor XI; Belongs to the peptidase S1 family.	0.952
F12	PLG	A0A2Y9MGJ8	A0A2Y9M5R2	LOW QUALITY PROTEIN: coagulation factor XII.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.961