STRINGSTRING
BCR BCR SFN SFN KDF1 KDF1 TGM1 TGM1 IFT74 IFT74 ST14 ST14 INTU INTU LOC111165064 LOC111165064 MED1 MED1 LATS1 LATS1 TMEM79 TMEM79 SHARPIN SHARPIN ACER1 ACER1 LOC111167902 LOC111167902 EXPH5 EXPH5 LOC111166378 LOC111166378 LOC111168862 LOC111168862 YAP1 YAP1 SPRR4 SPRR4 MADCAM1 MADCAM1 KRT4 KRT4 LOC111173973 LOC111173973 SAV1 SAV1 CASP3 CASP3 KRT79 KRT79 LOC111173974 LOC111173974 ANXA1 ANXA1 KRT8 KRT8 LOC111173970 LOC111173970 KRT7 KRT7 LATS2 LATS2 WNT5A WNT5A TP63 TP63 KRT78 KRT78 LOC111173971 LOC111173971 KRT80 KRT80 ADAM9 ADAM9 POU3F1 POU3F1 SCEL SCEL BCL11B BCL11B OPN3 OPN3 FOSL2 FOSL2 UGCG UGCG KEL KEL NOTCH1 NOTCH1 EZH2 EZH2 CDH3 CDH3 TSG101 TSG101 TXNIP TXNIP MAP2K1 MAP2K1 WNT16 WNT16 PPP3CA PPP3CA PAX6 PAX6 DSP DSP TGM3 TGM3 MAFB MAFB LOC111184719 LOC111184719 LOC111185338 LOC111185338 STK4 STK4 PALLD PALLD LOC111184716 LOC111184716 FOXN1 FOXN1 DNASE1L2 DNASE1L2 KAZN KAZN EPHA2 EPHA2 LOC111187154 LOC111187154 CERS3 CERS3 CLIC4 CLIC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCRBreakpoint cluster region protein isoform X1. (1275 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K isoform X2. (849 aa)
IFT74Intraflagellar transport protein 74 homolog isoform X1. (600 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
INTUProtein inturned isoform X1. (934 aa)
LOC111165064Plectin isoform X1. (4685 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
LATS1Serine/threonine-protein kinase LATS1. (1128 aa)
TMEM79Transmembrane protein 79. (395 aa)
SHARPINSharpin isoform X1. (484 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
LOC111167902Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
EXPH5Exophilin-5 isoform X1. (2002 aa)
LOC111166378Keratin, type I cytoskeletal 17-like isoform X1; Belongs to the intermediate filament family. (453 aa)
LOC111168862Keratin, type II cytoskeletal 8-like; Belongs to the intermediate filament family. (486 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (511 aa)
SPRR4LOW QUALITY PROTEIN: small proline-rich protein 4. (82 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1. (406 aa)
KRT4Keratin, type II cytoskeletal 4; Belongs to the intermediate filament family. (519 aa)
LOC111173973LOW QUALITY PROTEIN: keratin, type II cuticular Hb5-like; Belongs to the intermediate filament family. (506 aa)
SAV1Protein salvador homolog 1. (385 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa)
KRT79LOW QUALITY PROTEIN: keratin, type II cytoskeletal 79; Belongs to the intermediate filament family. (362 aa)
LOC111173974LOW QUALITY PROTEIN: keratin, type II cuticular Hb6-like; Belongs to the intermediate filament family. (486 aa)
ANXA1Annexin. (346 aa)
KRT8Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (489 aa)
LOC111173970Keratin, type II cytoskeletal 5-like; Belongs to the intermediate filament family. (594 aa)
KRT7Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family. (467 aa)
LATS2Serine/threonine-protein kinase LATS2. (1043 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (458 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
KRT78Keratin, type II cytoskeletal 78 isoform X1; Belongs to the intermediate filament family. (514 aa)
LOC111173971Keratin, type II cytoskeletal 6A-like; Belongs to the intermediate filament family. (588 aa)
KRT80Keratin, type II cytoskeletal 80; Belongs to the intermediate filament family. (452 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (841 aa)
POU3F1POU domain protein. (447 aa)
SCELSciellin isoform X1. (642 aa)
BCL11BB-cell lymphoma/leukemia 11B isoform X1. (903 aa)
OPN3LOW QUALITY PROTEIN: opsin-3. (515 aa)
FOSL2Fos-related antigen 2 isoform X1. (327 aa)
UGCGCeramide glucosyltransferase. (394 aa)
KELKell blood group glycoprotein isoform X1. (800 aa)
NOTCH1Neurogenic locus notch homolog protein 1 isoform X1. (2521 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (747 aa)
CDH3Cadherin-3 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (834 aa)
TSG101Tumor susceptibility gene 101 protein isoform X1. (429 aa)
TXNIPThioredoxin-interacting protein. (391 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PAX6Paired box protein Pax-6 isoform X1. (493 aa)
DSPDesmoplakin isoform X1. (2874 aa)
TGM3Protein-glutamine gamma-glutamyltransferase E. (691 aa)
MAFBTranscription factor MafB. (323 aa)
LOC111184719Interferon regulatory factor 6 isoform X1. (467 aa)
LOC111185338Palladin-like. (653 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (487 aa)
PALLDPalladin isoform X1. (656 aa)
LOC111184716Interferon regulatory factor 6 isoform X2. (485 aa)
FOXN1Forkhead box protein N1. (645 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (304 aa)
KAZNKazrin isoform X1. (874 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
CERS3Ceramide synthase 3. (389 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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