STRINGSTRING
RASAL1 RASAL1 KLHL22 KLHL22 MUL1 MUL1 PLAA PLAA SFN SFN SYT17 SYT17 COMMD5 COMMD5 F2 F2 NCBP1 NCBP1 SFRP2 SFRP2 POU4F2 POU4F2 SLC25A33 SLC25A33 TGFBR1 TGFBR1 KDM2B KDM2B IGF1 IGF1 CDH4 CDH4 NOL12 NOL12 EXOSC9 EXOSC9 NTN1 NTN1 CXCL16 CXCL16 EGFR EGFR CSNK2A1 CSNK2A1 LOC111164736 LOC111164736 DERL2 DERL2 DSCAM DSCAM DDX3X DDX3X HDGFL2 HDGFL2 PSMD10 PSMD10 MMP14 MMP14 GOLGA4 GOLGA4 DDX49 DDX49 CRABP2 CRABP2 EXOSC4 EXOSC4 TEAD1 TEAD1 USP47 USP47 ERBB2 ERBB2 SYT1 SYT1 SEMA4D SEMA4D ADNP2 ADNP2 FGFR1OP FGFR1OP TRPV2 TRPV2 SYT4 SYT4 LOC111166378 LOC111166378 UNC13A UNC13A WNT3A WNT3A SYT2 SYT2 AGPAT4 AGPAT4 CDKL5 CDKL5 CPNE9 CPNE9 YAP1 YAP1 CIB1 CIB1 BMPR2 BMPR2 BRAT1 BRAT1 ZFYVE27 ZFYVE27 SHTN1 SHTN1 MAP3K13 MAP3K13 SFRP1 SFRP1 SLC44A4 SLC44A4 N6AMT1 N6AMT1 LGI1 LGI1 FN1 FN1 CDKN2AIP CDKN2AIP UCN UCN HYAL1 HYAL1 MFSD2A MFSD2A EIF4G1 EIF4G1 ZNF639 ZNF639 TRIM32 TRIM32 FXN FXN TGFB2 TGFB2 EXOSC2 EXOSC2 SEMA7A SEMA7A MTPN MTPN ADAM10 ADAM10 SRF SRF ISLR ISLR TAF9B TAF9B LPAR3 LPAR3 IST1 IST1 ARMC12 ARMC12 ISLR2 ISLR2 NEDD4L NEDD4L MEGF8 MEGF8 CPNE5 CPNE5 BCL2 BCL2 LIMK1 LIMK1 NGF NGF SMAD7 SMAD7 INO80 INO80 LOC111181895 LOC111181895 HPN HPN WNT3 WNT3 SYT3 SYT3 LOC111181097 LOC111181097 SUPV3L1 SUPV3L1 EDN1 EDN1 RPTOR RPTOR SPHK1 SPHK1 SMURF1 SMURF1 EFNA5 EFNA5 RIMS1 RIMS1 DBNL DBNL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RASAL1rasGAP-activating-like protein 1 isoform X1. (813 aa)
KLHL22Kelch-like protein 22. (634 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1 isoform X1. (352 aa)
PLAAPhospholipase A-2-activating protein. (796 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
SYT17Synaptotagmin-17 isoform X1. (505 aa)
COMMD5COMM domain-containing protein 5 isoform X1. (283 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
NCBP1Nuclear cap-binding protein subunit 1 isoform X1. (790 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
POU4F2POU domain protein. (407 aa)
SLC25A33Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
KDM2BLysine-specific demethylase 2B isoform X1. (1324 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
CDH4Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
NOL12Nucleolar protein 12. (214 aa)
EXOSC9Exosome complex component RRP45. (437 aa)
NTN1Netrin-1. (604 aa)
CXCL16C-X-C motif chemokine 16 isoform X1. (316 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
LOC111164736LOW QUALITY PROTEIN: zinc finger protein 639-like. (488 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
DSCAMDown syndrome cell adhesion molecule isoform X2. (1577 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
HDGFL2Hepatoma-derived growth factor-related protein 2 isoform X1. (663 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
MMP14Matrix metalloproteinase-14. (582 aa)
GOLGA4Golgin subfamily A member 4 isoform X1. (2275 aa)
DDX49Probable ATP-dependent RNA helicase DDX49; Belongs to the DEAD box helicase family. (483 aa)
CRABP2Cellular retinoic acid-binding protein 2 isoform X1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (144 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X3. (523 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1375 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
SYT1Synaptotagmin-1 isoform X1. (422 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (863 aa)
ADNP2Activity-dependent neuroprotector homeobox protein 2 isoform X1. (1157 aa)
FGFR1OPFGFR1 oncogene partner isoform X1. (399 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
SYT4Synaptotagmin-4. (425 aa)
LOC111166378Keratin, type I cytoskeletal 17-like isoform X1; Belongs to the intermediate filament family. (453 aa)
UNC13AProtein unc-13 homolog A isoform X1. (1726 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SYT2Synaptotagmin-2 isoform X1. (428 aa)
AGPAT41-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1. (835 aa)
CDKL5Cyclin-dependent kinase-like 5 isoform X1. (960 aa)
CPNE9Copine-9 isoform X1. (587 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (511 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BRAT1BRCA1-associated ATM activator 1 isoform X1. (818 aa)
ZFYVE27Protrudin isoform X1. (407 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
SLC44A4Choline transporter-like protein 4 isoform X1; Belongs to the CTL (choline transporter-like) family. (706 aa)
N6AMT1hemK methyltransferase family member 2 isoform X1. (214 aa)
LGI1Leucine-rich glioma-inactivated protein 1 isoform X1. (641 aa)
FN1Fibronectin isoform X5. (2478 aa)
CDKN2AIPCDKN2A-interacting protein isoform X1. (582 aa)
UCNUrocortin. (126 aa)
HYAL1Hyaluronidase. (448 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform X1. (565 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform X1. (1608 aa)
ZNF639Zinc finger protein 639. (485 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32 isoform X1. (699 aa)
FXNFrataxin, mitochondrial. (213 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EXOSC2Exosome complex component RRP4. (293 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (665 aa)
MTPNMyotrophin. (118 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
SRFSerum response factor isoform X2. (535 aa)
ISLRImmunoglobulin superfamily containing leucine-rich repeat protein. (428 aa)
TAF9BTranscription initiation factor TFIID subunit 9B isoform X1. (250 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (355 aa)
IST1IST1 homolog isoform X1. (362 aa)
ARMC12Armadillo repeat-containing protein 12 isoform X2. (366 aa)
ISLR2Immunoglobulin superfamily containing leucine-rich repeat protein 2. (747 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X1. (1244 aa)
MEGF8LOW QUALITY PROTEIN: multiple epidermal growth factor-like domains protein 8. (2784 aa)
CPNE5Copine-5 isoform X3. (623 aa)
BCL2Apoptosis regulator Bcl-2. (233 aa)
LIMK1LIM domain kinase 1 isoform X1. (647 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
INO80DNA helicase INO80 isoform X1. (1563 aa)
LOC111181895Oncomodulin; Belongs to the parvalbumin family. (132 aa)
HPNSerine protease hepsin isoform X1; Belongs to the peptidase S1 family. (599 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (453 aa)
SYT3Synaptotagmin-3. (591 aa)
LOC111181097LOW QUALITY PROTEIN: CDKN2A-interacting protein-like. (392 aa)
SUPV3L1ATP-dependent RNA helicase SUPV3L1, mitochondrial. (787 aa)
EDN1Endothelin-1. (202 aa)
RPTORRegulatory-associated protein of mTOR isoform X7. (1335 aa)
SPHK1Sphingosine kinase 1 isoform X2. (484 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
RIMS1Regulating synaptic membrane exocytosis protein 1 isoform X44. (1678 aa)
DBNLDrebrin-like protein isoform X1. (430 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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