STRINGSTRING
IFIH1 IFIH1 SNW1 SNW1 PHB2 PHB2 NR5A1 NR5A1 NR4A1 NR4A1 RORB RORB RHOA RHOA NFKBIA NFKBIA LACC1 LACC1 TMF1 TMF1 VDR VDR CALCOCO1 CALCOCO1 RARG RARG NR4A2 NR4A2 CLPB CLPB ESR2 ESR2 ARNT ARNT RXRG RXRG YAP1 YAP1 NR5A2 NR5A2 RORC RORC GPER1 GPER1 LOC111169933 LOC111169933 NR2C1 NR2C1 NR2F6 NR2F6 NR2C2 NR2C2 DHX58 DHX58 FAM120B FAM120B CUNH1orf106 CUNH1orf106 LOC111167902 LOC111167902 AR AR KDM3A KDM3A NR1I3 NR1I3 ESR1 ESR1 THRA THRA MED1 MED1 STAT3 STAT3 PHB PHB RARA RARA RARB RARB SAFB SAFB NR2E1 NR2E1 NR1D2 NR1D2 YWHAH YWHAH NOD2 NOD2 THRB THRB ARID1A ARID1A CRKL CRKL AHR AHR POU4F2 POU4F2 NR3C2 NR3C2 UBE3A UBE3A PADI2 PADI2 NR4A3 NR4A3 RBFOX2 RBFOX2 NR2F2 NR2F2 TIFA TIFA NR1H4 NR1H4 LOC111185625 LOC111185625 LOC111185611 LOC111185611 NKX3-1 NKX3-1 RNF34 RNF34 NR1H2 NR1H2 AHRR AHRR OTULIN OTULIN UBR5 UBR5 CST11 CST11 DDX17 DDX17 PPARA PPARA ALPK1 ALPK1 HNF4A HNF4A NR1I2 NR1I2 ESRRB ESRRB RORA RORA RXRA RXRA PTF1A PTF1A ESRRG ESRRG NEDD4 NEDD4 ALDH1A2 ALDH1A2 PML PML FAM105A FAM105A NR6A1 NR6A1 PPARD PPARD PIM1 PIM1 NR2E3 NR2E3 TRIP4 TRIP4 RXRB RXRB DAXX DAXX ACTN4 ACTN4 LSM14A LSM14A PPARGC1B PPARGC1B NR3C1 NR3C1 NR2F1 NR2F1 RELA RELA NR1H3 NR1H3 DDX5 DDX5 ESRRA ESRRA SRC SRC ZMIZ1 ZMIZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFIH1Interferon-induced helicase C domain-containing protein 1. (1023 aa)
SNW1SNW domain-containing protein 1. (536 aa)
PHB2Prohibitin. (299 aa)
NR5A1Steroidogenic factor 1 isoform X1. (461 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (593 aa)
RORBNuclear receptor ROR-beta. (459 aa)
RHOATransforming protein RhoA. (193 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
LACC1Laccase domain-containing protein 1. (426 aa)
TMF1TATA element modulatory factor isoform X1. (1093 aa)
VDRVitamin D3 receptor isoform X1. (503 aa)
CALCOCO1Calcium-binding and coiled-coil domain-containing protein 1. (692 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2 isoform X1. (598 aa)
CLPBCaseinolytic peptidase B protein homolog isoform X1. (677 aa)
ESR2Estrogen receptor beta. (558 aa)
ARNTAryl hydrocarbon receptor nuclear translocator isoform X1. (790 aa)
RXRGRetinoic acid receptor RXR-gamma isoform X1. (463 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (511 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2 isoform X1. (501 aa)
RORCNuclear receptor ROR-gamma isoform X1. (544 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
LOC111169933LOW QUALITY PROTEIN: steroid hormone receptor ERR2-like. (432 aa)
NR2C1Nuclear receptor subfamily 2 group C member 1 isoform X1. (605 aa)
NR2F6Nuclear receptor subfamily 2 group F member 6. (413 aa)
NR2C2Nuclear receptor subfamily 2 group C member 2 isoform X1. (629 aa)
DHX58Probable ATP-dependent RNA helicase DHX58 isoform X1. (680 aa)
FAM120BConstitutive coactivator of peroxisome proliferator-activated receptor gamma isoform X1. (815 aa)
CUNH1orf106Uncharacterized protein C1orf106 homolog. (540 aa)
LOC111167902Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
ARAndrogen receptor. (893 aa)
KDM3ALysine-specific demethylase 3A isoform X1. (1322 aa)
NR1I3LOW QUALITY PROTEIN: nuclear receptor subfamily 1 group I member 3. (355 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
THRAThyroid hormone receptor alpha. (410 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PHBProhibitin. (272 aa)
RARARetinoic acid receptor alpha isoform X5. (584 aa)
RARBRetinoic acid receptor beta isoform X1. (448 aa)
SAFBScaffold attachment factor B1 isoform X1. (933 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1 isoform X1. (385 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2 isoform X1. (575 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa)
THRBThyroid hormone receptor beta isoform X3. (476 aa)
ARID1AAT-rich interactive domain-containing protein 1A isoform X1. (2287 aa)
CRKLCrk-like protein. (303 aa)
AHRAryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] (845 aa)
POU4F2POU domain protein. (407 aa)
NR3C2Mineralocorticoid receptor isoform X1. (983 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
PADI2Protein-arginine deiminase type-2. (665 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3 isoform X1. (641 aa)
RBFOX2RNA binding protein fox-1 homolog 2 isoform X1. (464 aa)
NR2F2COUP transcription factor 2 isoform X1. (414 aa)
TIFATRAF-interacting protein with FHA domain-containing protein A. (185 aa)
NR1H4Bile acid receptor isoform X1. (486 aa)
LOC111185625Hepatocyte nuclear factor 4-gamma-like. (383 aa)
LOC111185611Hepatocyte nuclear factor 4-gamma isoform X1. (462 aa)
NKX3-1Homeobox protein Nkx-3.1. (241 aa)
RNF34E3 ubiquitin-protein ligase RNF34 isoform X1. (376 aa)
NR1H2Oxysterols receptor LXR-beta isoform X1. (450 aa)
AHRRAryl hydrocarbon receptor repressor. (693 aa)
OTULINUbiquitin thioesterase otulin isoform X1. (352 aa)
UBR5E3 ubiquitin-protein ligase UBR5 isoform X1. (2798 aa)
CST11Cystatin-11. (137 aa)
DDX17Probable ATP-dependent RNA helicase DDX17 isoform X1; Belongs to the DEAD box helicase family. (652 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
ALPK1Alpha-protein kinase 1 isoform X1. (1244 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (484 aa)
NR1I2LOW QUALITY PROTEIN: nuclear receptor subfamily 1 group I member 2. (414 aa)
ESRRBSteroid hormone receptor ERR2 isoform X4. (443 aa)
RORANuclear receptor ROR-alpha isoform X1. (523 aa)
RXRARetinoic acid receptor RXR-alpha isoform X1. (495 aa)
PTF1ALOW QUALITY PROTEIN: pancreas transcription factor 1 subunit alpha. (326 aa)
ESRRGEstrogen-related receptor gamma isoform X1. (458 aa)
NEDD4E3 ubiquitin-protein ligase NEDD4 isoform X3. (1319 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
PMLProtein PML isoform X1. (861 aa)
FAM105AInactive ubiquitin thioesterase FAM105A. (356 aa)
NR6A1Nuclear receptor subfamily 6 group A member 1 isoform X1. (497 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (347 aa)
NR2E3Photoreceptor-specific nuclear receptor. (411 aa)
TRIP4Activating signal cointegrator 1. (581 aa)
RXRBRetinoic acid receptor RXR-beta isoform X1. (538 aa)
DAXXDeath domain-associated protein 6 isoform X1. (742 aa)
ACTN4Alpha-actinin-4 isoform X5. (933 aa)
LSM14AProtein LSM14 homolog A isoform X1. (515 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1173 aa)
NR3C1Glucocorticoid receptor isoform X1. (777 aa)
NR2F1COUP transcription factor 1. (422 aa)
RELATranscription factor p65 isoform X1. (562 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
DDX5Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (614 aa)
ESRRASteroid hormone receptor ERR1. (422 aa)
SRCTyrosine-protein kinase. (562 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1 isoform X1. (1071 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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