19 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	THBS1	Thrombospondin-1. (1170 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	PLA2G10	Phospholipase A(2). (159 aa)
	APOC3	Apolipoprotein C-III. (99 aa)
	APOA2	Apolipoprotein A-II. (103 aa)
	ITGAV	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
	ABCG5	LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5. (652 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9 isoform X1. (692 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	IRS2	Insulin receptor substrate 2. (1347 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (461 aa)
	NR1H2	Oxysterols receptor LXR-beta isoform X1. (450 aa)
	FIS1	Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (789 aa)
	NR1H3	Oxysterols receptor LXR-alpha isoform X1. (447 aa)
	CRY2	Cryptochrome-2. (588 aa)
	SREBF2	Sterol regulatory element-binding protein 2 isoform X1. (1135 aa)
	CRY1	Cryptochrome-1 isoform X1. (587 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG5	APOC3	A0A2Y9N4M7	A0A2Y9LYW0	LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5.	Apolipoprotein C-III.	0.429
ABCG5	NR1H3	A0A2Y9N4M7	A0A2Y9PPY7	LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5.	Oxysterols receptor LXR-alpha isoform X1.	0.662
ABCG5	PCSK9	A0A2Y9N4M7	A0A2Y9NB79	LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5.	Proprotein convertase subtilisin/kexin type 9 isoform X1.	0.438
ABCG5	SREBF2	A0A2Y9N4M7	A0A2Y9QB94	LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5.	Sterol regulatory element-binding protein 2 isoform X1.	0.440
AKT1	AKT2	A0A2Y9NBQ2	A0A2Y9PDM4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	IRS2	A0A2Y9NBQ2	A0A2Y9NC55	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 2.	0.446
AKT2	AKT1	A0A2Y9PDM4	A0A2Y9NBQ2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT2	IRS2	A0A2Y9PDM4	A0A2Y9NC55	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin receptor substrate 2.	0.446
APOA2	APOC3	A0A2Y9LZM5	A0A2Y9LYW0	Apolipoprotein A-II.	Apolipoprotein C-III.	0.994
APOC3	ABCG5	A0A2Y9LYW0	A0A2Y9N4M7	Apolipoprotein C-III.	LOW QUALITY PROTEIN: ATP-binding cassette sub-family G member 5.	0.429
APOC3	APOA2	A0A2Y9LYW0	A0A2Y9LZM5	Apolipoprotein C-III.	Apolipoprotein A-II.	0.994
CRY1	CRY2	A0A2Y9QDN2	A0A2Y9PRL3	Cryptochrome-1 isoform X1.	Cryptochrome-2.	0.994
CRY2	CRY1	A0A2Y9PRL3	A0A2Y9QDN2	Cryptochrome-2.	Cryptochrome-1 isoform X1.	0.994
IRS2	AKT1	A0A2Y9NC55	A0A2Y9NBQ2	Insulin receptor substrate 2.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.446
IRS2	AKT2	A0A2Y9NC55	A0A2Y9PDM4	Insulin receptor substrate 2.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.446
IRS2	PTPN11	A0A2Y9NC55	A0A2Y9QEG1	Insulin receptor substrate 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.891
ITGAV	ITGB3	A0A2Y9MPN9	A0A2Y9PCY7	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGAV	THBS1	A0A2Y9MPN9	A0A2Y9PKH8	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	Thrombospondin-1.	0.966
ITGB3	ITGAV	A0A2Y9PCY7	A0A2Y9MPN9	Integrin beta; Belongs to the integrin beta chain family.	Integrin alpha-V isoform X2; Belongs to the integrin alpha chain family.	0.999
ITGB3	THBS1	A0A2Y9PCY7	A0A2Y9PKH8	Integrin beta; Belongs to the integrin beta chain family.	Thrombospondin-1.	0.973